SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		5 / 12 LEU A 544
LEU A 282
GLY A 529
ALA A 530
SER A 520
 None
 1.07A 1cqeA-1g01A:
undetectable		 1cqeA-1g01A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 6 ALA A 530
SER A 447
ARG A 292
LEU A 521
 None
 1.21A 1gahA-1g01A:
undetectable		 1gahA-1g01A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 ASP A 577
THR A 532
PRO A 533
 None
 0.54A 2pynB-1g01A:
undetectable		 2pynB-1g01A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 ASP A 577
THR A 532
PRO A 533
 None
 0.54A 2q64B-1g01A:
undetectable		 2q64B-1g01A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 ASP A 577
THR A 532
PRO A 533
 None
 0.55A 2qakB-1g01A:
undetectable		 2qakB-1g01A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		5 / 12 ASN A 372
GLU A 373
HIS A 442
GLU A 485
TRP A 519
 CD  A 591 ( 4.8A)
CD  A 591 (-2.2A)
None
CD  A 591 (-2.8A)
None
 0.59A 2v3dA-1g01A:
16.3		 2v3dA-1g01A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 8 GLN A 258
ARG A 567
TRP A 486
THR A 445
 None
 1.33A 2vxaF-1g01A:
0.0
2vxaG-1g01A:
0.0
2vxaI-1g01A:
0.0		 2vxaF-1g01A:
13.83
2vxaG-1g01A:
13.83
2vxaI-1g01A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 MET A 262
VAL A 312
GLU A 369
 None
 0.88A 2x9gA-1g01A:
undetectable		 2x9gA-1g01A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 MET A 290
GLU A 369
ASN A 417
 None
 1.11A 3a27A-1g01A:
undetectable		 3a27A-1g01A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 8 ALA A 281
PRO A 546
GLU A 555
THR A 542
 None
 0.79A 3dtuC-1g01A:
undetectable
3dtuD-1g01A:
0.0		 3dtuC-1g01A:
20.63
3dtuD-1g01A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		5 / 12 GLY A 529
ASP A 494
GLY A 266
GLN A 268
PRO A 533
 None
 1.19A 3eeyD-1g01A:
undetectable		 3eeyD-1g01A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 HIS A 331
PHE A 349
PHE A 350
 None
 0.59A 3lk0D-1g01A:
undetectable		 3lk0D-1g01A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		5 / 12 LEU A 544
LEU A 282
GLY A 529
ALA A 530
SER A 520
 None
 1.15A 3pghA-1g01A:
0.0		 3pghA-1g01A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 ASP A 577
THR A 532
PRO A 533
 None
 0.59A 3tkgD-1g01A:
undetectable		 3tkgD-1g01A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 6 PRO A 338
GLY A 336
ASN A 377
ASN A 372
 None
None
None
CD  A 591 ( 4.8A)
 0.84A 3zqtA-1g01A:
undetectable		 3zqtA-1g01A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 6 HIS A 442
GLU A 485
ASP A 329
SER A 263
 None
CD  A 591 (-2.8A)
None
None
 1.00A 4apjA-1g01A:
undetectable
4apjP-1g01A:
undetectable		 4apjA-1g01A:
20.20
4apjP-1g01A:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 8 GLU A 399
GLU A 396
TYR A 397
GLY A 416
 None
CD  A 588 ( 2.5A)
None
None
 0.92A 4fgzA-1g01A:
undetectable
4fgzB-1g01A:
undetectable		 4fgzA-1g01A:
21.92
4fgzB-1g01A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 LEU A 259
MET A 290
ASP A 410
 None
 0.77A 4j7xB-1g01A:
2.9		 4j7xB-1g01A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 5 ASN A 372
HIS A 331
GLU A 369
THR A 484
 CD  A 591 ( 4.8A)
None
None
None
 1.48A 4p6sA-1g01A:
0.0		 4p6sA-1g01A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 4 SER A 461
GLU A 392
GLU A 399
ASP A 429
 None
 1.36A 4pclB-1g01A:
0.9		 4pclB-1g01A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 4 THR A 522
GLY A 493
ASP A 494
SER A 520
 None
 1.31A 4rfqA-1g01A:
undetectable		 4rfqA-1g01A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		6 / 12 SER A 263
GLY A 416
SER A 421
GLU A 373
ASN A 372
ALA A 398
 None
None
None
CD  A 591 (-2.2A)
CD  A 591 ( 4.8A)
None
 1.39A 4u95B-1g01A:
0.4		 4u95B-1g01A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		5 / 12 LEU A 544
LEU A 282
GLY A 529
ALA A 530
SER A 520
 None
 1.09A 5jvzA-1g01A:
0.0		 5jvzA-1g01A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		5 / 12 LEU A 544
LEU A 282
GLY A 529
ALA A 530
SER A 520
 None
 1.12A 5jvzB-1g01A:
0.0		 5jvzB-1g01A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 6 GLY A 487
THR A 488
SER A 489
ASN A 518
 None
 0.80A 5k4pA-1g01A:
1.6		 5k4pA-1g01A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 GLU A 562
TYR A 563
ARG A 567
 None
 0.84A 5uunA-1g01A:
0.0		 5uunA-1g01A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 GLU A 562
TYR A 563
ARG A 567
 None
 0.83A 5uunB-1g01A:
0.0		 5uunB-1g01A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		3 / 3 THR A 484
GLU A 369
HIS A 331
 None
 0.91A 5xiqB-1g01A:
undetectable		 5xiqB-1g01A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 6 VAL A 326
TYR A 357
ILE A 316
GLU A 317
 None
 1.05A 5z3jA-1g01A:
undetectable		 5z3jA-1g01A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1g01 ENDOGLUCANASE
(Bacillus
sp.
KSM-635) 		4 / 8 HIS A 331
HIS A 448
GLU A 485
GLU A 526
 None
None
CD  A 591 (-2.8A)
None
 1.16A 6mn4D-1g01A:
0.0		 6mn4D-1g01A:
21.64