SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 GLN A 352
PRO A 370
GLU A 342
ASP A 349
 None
 1.24A 1dtlA-1g0dA:
undetectable		 1dtlA-1g0dA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 6 LEU A 506
ALA A 563
LEU A 565
THR A 576
 None
 0.70A 1ictB-1g0dA:
0.1		 1ictB-1g0dA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 VAL A 394
SER A 424
VAL A 436
GLU A 336
 None
 0.95A 1jtvA-1g0dA:
undetectable		 1jtvA-1g0dA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 6 ASP A 566
GLY A 572
ILE A 412
ARG A 410
 None
 0.90A 1mt1G-1g0dA:
0.0
1mt1J-1g0dA:
0.9		 1mt1G-1g0dA:
5.35
1mt1J-1g0dA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 7 ILE A 412
ARG A 410
ASP A 566
GLY A 572
 None
 0.88A 1mt1H-1g0dA:
0.9
1mt1K-1g0dA:
0.0		 1mt1H-1g0dA:
10.62
1mt1K-1g0dA:
5.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 ALA A 276
VAL A 278
TRP A 175
 None
 0.88A 1nrmA-1g0dA:
undetectable		 1nrmA-1g0dA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 ALA A 276
VAL A 278
TRP A 175
 None
 0.88A 1nrmB-1g0dA:
undetectable		 1nrmB-1g0dA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 ALA A 276
VAL A 278
TRP A 175
 None
 0.84A 1nt5A-1g0dA:
undetectable		 1nt5A-1g0dA:
1.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 ALA A 276
VAL A 278
TRP A 175
 None
 0.84A 1nt5B-1g0dA:
undetectable		 1nt5B-1g0dA:
1.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 SER A  41
ASN A  18
GLN A  38
PHE A  40
 None
 1.35A 1rs6A-1g0dA:
0.0		 1rs6A-1g0dA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 12 ASP A 355
PRO A 372
ALA A 375
ILE A 376
ARG A 341
 None
 1.42A 1s14B-1g0dA:
0.0		 1s14B-1g0dA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 PHE A 620
LEU A 587
LEU A 670
LEU A 615
 None
 1.04A 2bfpD-1g0dA:
0.0		 2bfpD-1g0dA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 ILE A 128
ARG A  14
THR A  96
LEU A  97
 None
 0.93A 2einA-1g0dA:
0.0
2einJ-1g0dA:
0.0		 2einA-1g0dA:
19.23
2einJ-1g0dA:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 ASP A 147
TYR A 154
TRP A 351
TYR A 429
 None
None
SO4  A 696 (-4.2A)
None
 1.46A 2ha2A-1g0dA:
undetectable		 2ha2A-1g0dA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 ASP A 147
TYR A 154
TRP A 351
TYR A 429
 None
None
SO4  A 696 (-4.2A)
None
 1.46A 2ha2B-1g0dA:
undetectable		 2ha2B-1g0dA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 GLY A 106
ARG A 209
TYR A 108
 None
 0.77A 2opxA-1g0dA:
undetectable		 2opxA-1g0dA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 12 ASP A 303
HIS A 300
GLU A 393
HIS A 332
ASP A 355
 None
 1.27A 2pgfA-1g0dA:
undetectable		 2pgfA-1g0dA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 12 ILE A 633
MET A 164
PHE A 331
TYR A 515
ALA A 276
 None
 1.37A 2x2nD-1g0dA:
undetectable		 2x2nD-1g0dA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_B_TC9B1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 11 SER A 318
THR A 398
TYR A 400
SER A 328
SER A 327
 None
 1.48A 2xytB-1g0dA:
0.6
2xytC-1g0dA:
0.1
2xytG-1g0dA:
0.2		 2xytB-1g0dA:
17.12
2xytC-1g0dA:
17.12
2xytG-1g0dA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 6 ILE A 128
ARG A  14
THR A  96
LEU A  97
 None
 0.82A 3ag1N-1g0dA:
0.0
3ag1W-1g0dA:
0.0		 3ag1N-1g0dA:
19.23
3ag1W-1g0dA:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 PHE A 134
VAL A 155
LEU A 151
PRO A 289
 None
 0.83A 3bgdB-1g0dA:
undetectable		 3bgdB-1g0dA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 4 VAL A 155
ARG A  36
ILE A  33
THR A 290
 None
 1.25A 3cl9A-1g0dA:
undetectable		 3cl9A-1g0dA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 7 LEU A 506
ALA A 563
LEU A 565
THR A 576
 None
 0.58A 3d2tA-1g0dA:
undetectable		 3d2tA-1g0dA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 6 ILE A 105
PHE A  40
PHE A 130
TYR A 108
 None
 1.31A 3elzB-1g0dA:
0.0		 3elzB-1g0dA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 LEU A 256
TRP A 259
GLY A 230
 None
 0.58A 3l35A-1g0dA:
0.0
3l35H-1g0dA:
undetectable		 3l35A-1g0dA:
5.22
3l35H-1g0dA:
2.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 LEU A 256
TRP A 259
GLY A 230
 None
 0.54A 3l35B-1g0dA:
undetectable
3l35K-1g0dA:
undetectable		 3l35B-1g0dA:
5.22
3l35K-1g0dA:
2.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 ARG A 669
ASP A 487
GLN A 524
 None
 0.91A 3lcvB-1g0dA:
undetectable		 3lcvB-1g0dA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 ARG A 409
LEU A 311
THR A 398
 None
 0.64A 3oxcA-1g0dA:
undetectable		 3oxcA-1g0dA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 11 ILE A 580
ALA A 480
PHE A 488
LEU A 582
TYR A 169
 None
 1.30A 3qg2B-1g0dA:
undetectable		 3qg2B-1g0dA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_D_T1CD401_1
(TETX2 PROTEIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 10 HIS A  22
GLN A  73
ASN A  85
GLY A  77
GLY A  37
 None
 1.49A 3v3oD-1g0dA:
0.0		 3v3oD-1g0dA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 5 LEU A 192
ALA A 198
MET A 222
THR A 218
 None
 1.33A 3vasB-1g0dA:
undetectable		 3vasB-1g0dA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 12 LEU A 286
CYH A 285
ILE A 105
VAL A 264
ASP A 193
 None
 1.18A 3vw1D-1g0dA:
0.0		 3vw1D-1g0dA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 7 LEU A 506
ALA A 563
LEU A 565
THR A 576
 None
 0.48A 4d7bA-1g0dA:
undetectable		 4d7bA-1g0dA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 ASN A 176
GLY A 624
ALA A 625
THR A 281
 None
 0.86A 4eyrB-1g0dA:
0.0		 4eyrB-1g0dA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 6 LEU A 506
ALA A 563
LEU A 565
THR A 576
 None
 0.64A 4ikiB-1g0dA:
undetectable		 4ikiB-1g0dA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 LEU A 506
ALA A 563
LEU A 565
THR A 576
 None
 0.62A 4ikjA-1g0dA:
0.3
4ikjB-1g0dA:
0.1		 4ikjA-1g0dA:
14.08
4ikjB-1g0dA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 LEU A 588
SER A 606
THR A 608
SER A 646
 None
 0.89A 4ikkA-1g0dA:
0.0
4ikkB-1g0dA:
0.1		 4ikkA-1g0dA:
14.08
4ikkB-1g0dA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 8 VAL A 390
GLY A 382
PRO A 372
VAL A 373
ILE A 376
 None
 1.36A 4ll3A-1g0dA:
undetectable		 4ll3A-1g0dA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 8 VAL A 577
TYR A 400
ILE A 399
VAL A 302
 None
 0.86A 4ma7A-1g0dA:
0.0		 4ma7A-1g0dA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 ARG A 659
ASP A 159
ARG A 655
 None
 0.86A 4mx0A-1g0dA:
undetectable		 4mx0A-1g0dA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 6 VAL A 335
LEU A 354
PHE A 180
MET A 156
 None
 1.13A 4o1zA-1g0dA:
0.0		 4o1zA-1g0dA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 7 VAL A  69
ILE A  70
LEU A  95
LEU A  97
 None
 0.85A 4xo7A-1g0dA:
undetectable		 4xo7A-1g0dA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		3 / 3 PRO A 212
ILE A  33
SER A 340
 None
 0.70A 5fsaA-1g0dA:
0.0		 5fsaA-1g0dA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 6 LEU A 506
ALA A 563
LEU A 565
THR A 576
 None
 0.65A 5l4iA-1g0dA:
3.6		 5l4iA-1g0dA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 7 GLY A 251
GLU A 623
ALA A 630
ASP A 664
 None
 0.96A 5mvsA-1g0dA:
undetectable		 5mvsA-1g0dA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 6 ILE A 128
ARG A  14
THR A  96
LEU A  97
 None
 1.00A 5zcoN-1g0dA:
0.0
5zcoW-1g0dA:
0.0		 5zcoN-1g0dA:
19.23
5zcoW-1g0dA:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 10 PHE A 189
LEU A 192
ASP A 205
GLY A  63
ILE A 105
 None
 1.06A 6ebpD-1g0dA:
undetectable		 6ebpD-1g0dA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 11 PHE A 189
LEU A 192
ASP A 205
GLY A  63
ILE A 105
 None
 1.07A 6ebzA-1g0dA:
undetectable		 6ebzA-1g0dA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 11 PHE A 189
LEU A 192
ASP A 205
GLY A  63
ILE A 105
 None
 1.07A 6ebzB-1g0dA:
undetectable		 6ebzB-1g0dA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 11 PHE A 189
LEU A 192
ASP A 205
GLY A  63
ILE A 105
 None
 1.06A 6ebzD-1g0dA:
undetectable		 6ebzD-1g0dA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 11 PHE A 189
LEU A 192
ASP A 205
GLY A  63
ILE A 105
 None
 0.95A 6gp2A-1g0dA:
undetectable		 6gp2A-1g0dA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		5 / 11 PHE A 189
LEU A 192
ASP A 205
GLY A  63
ILE A 105
 None
 0.94A 6gp2B-1g0dA:
undetectable		 6gp2B-1g0dA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 7 ILE A 128
ARG A  14
THR A  96
LEU A  97
 None
 0.85A 6nmfA-1g0dA:
0.0
6nmfJ-1g0dA:
0.0		 6nmfA-1g0dA:
19.23
6nmfJ-1g0dA:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 7 ILE A 128
ARG A  14
THR A  96
LEU A  97
 None
 0.83A 6nmpA-1g0dA:
0.0
6nmpJ-1g0dA:
0.0		 6nmpA-1g0dA:
19.23
6nmpJ-1g0dA:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE
(Pagrus
major) 		4 / 5 ILE A 128
ARG A  14
THR A  96
LEU A  97
 None
 0.92A 6nmpN-1g0dA:
0.0
6nmpW-1g0dA:
0.0		 6nmpN-1g0dA:
19.23
6nmpW-1g0dA:
6.73