SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 5 LYS A 187
ALA A 188
ASP A 126
GLY A 124
 None
None
MAN  A 329 ( 4.9A)
None
 1.21A 1e7bA-1g0vA:
undetectable		 1e7bA-1g0vA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 5 LYS A 187
ALA A 188
ASP A 126
GLY A 124
 None
None
MAN  A 329 ( 4.9A)
None
 0.91A 1e7cA-1g0vA:
undetectable		 1e7cA-1g0vA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 212
GLU A 191
LEU A 298
ARG A 186
LEU A 223
 None
 1.15A 1g50A-1g0vA:
undetectable		 1g50A-1g0vA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 9 ASP A  32
GLY A  34
ILE A  73
GLY B  21
ILE A 120
 None
 0.91A 1hpvA-1g0vA:
7.7		 1hpvA-1g0vA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 223
PRO A 224
LEU A 227
 None
 0.43A 1hrkA-1g0vA:
undetectable		 1hrkA-1g0vA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  32
GLY A  34
ILE A  73
GLY B  21
ILE A 120
 None
 0.87A 1muiB-1g0vA:
7.5		 1muiB-1g0vA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 THR A 218
LEU A 223
PHE A 260
VAL A 192
ALA A 212
 None
 1.24A 1q23H-1g0vA:
0.0
1q23I-1g0vA:
undetectable		 1q23H-1g0vA:
20.71
1q23I-1g0vA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 8 ALA A 213
TYR A 189
GLY A 302
GLY A 217
 None
 0.85A 1rukH-1g0vA:
undetectable
1rukL-1g0vA:
undetectable		 1rukH-1g0vA:
20.85
1rukL-1g0vA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 HIS A   2
THR A 166
GLU A 164
ASP A  93
GLY A   0
 None
 1.42A 1v8bC-1g0vA:
undetectable		 1v8bC-1g0vA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 THR A 268
LEU A 258
ILE A 269
PHE A 262
LEU A 223
 None
 1.16A 1wsvA-1g0vA:
0.4		 1wsvA-1g0vA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 THR A 268
LEU A 258
ILE A 269
PHE A 262
LEU A 223
 None
 1.17A 1wsvB-1g0vA:
0.0		 1wsvB-1g0vA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  32
GLY A  34
ILE A  73
GLY B  21
ILE A 120
 None
 0.74A 2hs1B-1g0vA:
7.3		 2hs1B-1g0vA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 220
ILE A 286
SER A 284
LYS B  16
 None
 1.16A 2othA-1g0vA:
0.0		 2othA-1g0vA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 123
LEU A  94
PHE A 153
 None
 0.74A 2pgrA-1g0vA:
undetectable		 2pgrA-1g0vA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 223
PRO A 224
LEU A 227
 None
 0.42A 2qd5B-1g0vA:
undetectable		 2qd5B-1g0vA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 10 ASP A  32
GLY A  34
ILE A  73
GLY B  21
ILE A 120
 None
 0.90A 2r5qD-1g0vA:
7.6		 2r5qD-1g0vA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 9 PHE A 267
ASP A 303
LEU A 306
GLY A 302
TYR A  14
 None
 1.44A 2tsrD-1g0vA:
0.0		 2tsrD-1g0vA:
21.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		6 / 12 ASP A  32
GLY A  34
SER A  35
PHE A 117
ASP A 215
GLY A 217
 None
 0.52A 2v0zC-1g0vA:
43.4		 2v0zC-1g0vA:
38.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  32
GLY A  34
PHE A 117
ASP A 215
GLY A 217
 None
 0.53A 2v0zO-1g0vA:
43.5		 2v0zO-1g0vA:
38.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 306
ILE A 221
LEU A 223
VAL A 192
VAL A 320
 None
 1.16A 2ygpA-1g0vA:
0.0		 2ygpA-1g0vA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 212
GLU A 191
LEU A 298
ARG A 186
LEU A 223
 None
 1.20A 3erdA-1g0vA:
undetectable		 3erdA-1g0vA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g0v PROTEASE A INHIBITOR
3
(Saccharomyces
cerevisiae) 		4 / 4 ASP B  22
GLY B  21
LYS B  18
GLU B  17
 None
 1.35A 3hznD-1g0vB:
undetectable		 3hznD-1g0vB:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_1
(O-METHYLTRANSFERASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 4 ASP A  87
SER A  85
PHE A 101
SER A  90
 None
 1.47A 3i5uA-1g0vA:
undetectable		 3i5uA-1g0vA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 11 ASP A  32
ASN A  37
ILE A  73
GLY B  21
ILE A 120
 None
 0.98A 3lzvB-1g0vA:
7.3		 3lzvB-1g0vA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 9 PHE A 291
ILE A 300
ALA A 299
ALA A 228
THR A 287
 None
 1.24A 3mdtA-1g0vA:
0.0		 3mdtA-1g0vA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  32
GLY A  34
ILE A  73
GLY B  21
ILE A 120
 None
 0.88A 3nu5A-1g0vA:
7.3		 3nu5A-1g0vA:
16.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
ILE A 300
 None
 0.60A 3q70A-1g0vA:
35.0		 3q70A-1g0vA:
33.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
THR A 218
 None
 0.68A 3q70A-1g0vA:
35.0		 3q70A-1g0vA:
33.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1g0v PROTEINASE A
PROTEASE A INHIBITOR
3
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU B  19
ASP B  22
ALA B  23
TYR A 189
 None
 1.20A 3rodD-1g0vB:
undetectable		 3rodD-1g0vB:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 221
LEU A 223
PHE A 194
GLY A 196
 None
 0.90A 3selX-1g0vA:
undetectable		 3selX-1g0vA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 221
LEU A 223
PHE A 194
GLY A 196
 None
 0.96A 3sj1X-1g0vA:
undetectable		 3sj1X-1g0vA:
13.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
ILE A 300
 None
 0.55A 3tneA-1g0vA:
35.3		 3tneA-1g0vA:
30.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
ILE A 300
 None
 0.54A 3tneB-1g0vA:
35.2		 3tneB-1g0vA:
30.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 8 THR A 222
PRO A 224
GLY A 296
PHE A 291
 None
 0.88A 3tzfB-1g0vA:
undetectable		 3tzfB-1g0vA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 223
PRO A 224
LEU A 227
 None
 0.37A 3w1wB-1g0vA:
undetectable		 3w1wB-1g0vA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 1g0v PROTEINASE A
PROTEASE A INHIBITOR
3
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 12 TYR A 189
LEU B  19
ILE A 128
VAL B  26
ASP A  32
 None
 1.15A 4a6dA-1g0vA:
0.0		 4a6dA-1g0vA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 11 GLY A  34
GLY A 217
ILE A 214
ASP A  32
ASN A  37
 None
 0.90A 4dcmA-1g0vA:
undetectable		 4dcmA-1g0vA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 223
PRO A 224
LEU A 227
ILE A 197
 None
 0.94A 4f4dB-1g0vA:
undetectable		 4f4dB-1g0vA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 5 ALA A 102
ILE A  73
LEU A  80
ASN A  37
 None
 1.17A 4g19A-1g0vA:
undetectable		 4g19A-1g0vA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 221
LEU A 223
PHE A 194
GLY A 196
 None
 0.91A 4hajA-1g0vA:
undetectable		 4hajA-1g0vA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 221
LEU A 223
PHE A 194
GLY A 196
 None
 0.85A 4hb6A-1g0vA:
undetectable		 4hb6A-1g0vA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 167
GLN A  99
LEU A  20
ILE A  18
LEU A  31
 None
 1.35A 4k38B-1g0vA:
undetectable		 4k38B-1g0vA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 269
PHE A 305
LEU A 182
VAL A 320
LEU A 322
 None
 0.91A 4km2B-1g0vA:
undetectable		 4km2B-1g0vA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 11 ASP A  32
GLY A  34
ILE A  73
GLY B  21
ILE A 120
 None
 0.96A 4njvC-1g0vA:
7.3		 4njvC-1g0vA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 304
GLN A 244
GLY A 243
 None
 0.61A 4odoC-1g0vA:
undetectable		 4odoC-1g0vA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1g0v PROTEASE A INHIBITOR
3
PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 131
VAL A 133
SER A  35
LEU A  80
ASP B  22
 None
NAG  A 332 (-3.2A)
None
None
None
 1.32A 4pevC-1g0vA:
0.0		 4pevC-1g0vA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 215
ASP A  32
ASN A  37
 None
 0.66A 4q5mA-1g0vA:
9.4		 4q5mA-1g0vA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 196
ILE A 214
ALA A 213
GLY A 210
PHE A 194
 None
 1.10A 4r29D-1g0vA:
0.0		 4r29D-1g0vA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 9 ALA A 212
GLU A 191
LEU A 298
ARG A 186
LEU A 223
 None
 1.22A 5dx3B-1g0vA:
undetectable		 5dx3B-1g0vA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 212
GLU A 191
LEU A 298
ARG A 186
LEU A 223
 None
 1.16A 5dxbA-1g0vA:
undetectable		 5dxbA-1g0vA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 212
GLU A 191
LEU A 298
ARG A 186
LEU A 223
 None
 1.17A 5dxbB-1g0vA:
undetectable		 5dxbB-1g0vA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 212
GLU A 191
LEU A 298
ARG A 186
LEU A 223
 None
 1.17A 5dxeB-1g0vA:
undetectable		 5dxeB-1g0vA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 175
ARG A 150
ILE A 312
ILE A 170
 None
 1.03A 5dzk4-1g0vA:
undetectable
5dzkg-1g0vA:
undetectable
5dzkm-1g0vA:
undetectable
5dzkn-1g0vA:
undetectable		 5dzk4-1g0vA:
1.36
5dzkg-1g0vA:
21.36
5dzkm-1g0vA:
19.29
5dzkn-1g0vA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 207
PHE A 194
GLY A 210
TYR A 203
 None
None
None
NAG  A 501 ( 3.8A)
 0.95A 5flcB-1g0vA:
undetectable		 5flcB-1g0vA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 207
PHE A 194
GLY A 210
TYR A 203
 None
None
None
NAG  A 501 ( 3.8A)
 0.95A 5flcF-1g0vA:
undetectable		 5flcF-1g0vA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 212
GLU A 191
LEU A 298
ARG A 186
LEU A 223
 None
 1.07A 5gtrA-1g0vA:
undetectable		 5gtrA-1g0vA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 8 LEU A   6
LEU A 155
LEU A 123
TYR A 313
LEU A  31
 None
 1.21A 5jqbA-1g0vA:
undetectable
5jqbB-1g0vA:
0.0		 5jqbA-1g0vA:
23.94
5jqbB-1g0vA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 12 HIS A   2
THR A 166
GLU A 164
ASP A  93
GLY A   0
 None
 1.43A 5utuH-1g0vA:
undetectable		 5utuH-1g0vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 212
GLU A 191
LEU A 298
ARG A 186
LEU A 223
 None
 1.21A 5wgqB-1g0vA:
undetectable		 5wgqB-1g0vA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1g0v PROTEINASE A
PROTEASE A INHIBITOR
3
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 12 LEU A 298
GLY A  34
ALA B  23
THR A  33
PHE A 151
 None
 1.34A 5x6yA-1g0vA:
0.0		 5x6yA-1g0vA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 1g0v PROTEINASE A
PROTEASE A INHIBITOR
3
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 12 ASP A  32
GLY A  34
ILE A  73
GLY B  21
ILE A 120
 None
 0.85A 6dh6B-1g0vA:
7.5		 6dh6B-1g0vA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 7 HIS A   2
GLU A 164
ASP A 171
GLU A 172
 None
 1.40A 6mn4F-1g0vA:
0.0		 6mn4F-1g0vA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 4 HIS A  53
LEU A  80
TYR A  75
GLY A 109
 None
 1.40A 6n91A-1g0vA:
undetectable		 6n91A-1g0vA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1g0v PROTEINASE A
(Saccharomyces
cerevisiae) 		4 / 4 HIS A  53
LEU A  80
TYR A  75
GLY A 109
 None
 1.41A 6n91B-1g0vA:
undetectable		 6n91B-1g0vA:
14.89