SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g0y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 7 GLU R  11
GLU R 217
ILE R 308
LEU R  88
 None
 0.92A 1q0yH-1g0yR:
5.6
1q0yL-1g0yR:
4.9		 1q0yH-1g0yR:
19.94
1q0yL-1g0yR:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 7 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.86A 1rxcC-1g0yR:
undetectable		 1rxcC-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 7 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.91A 1rxcD-1g0yR:
undetectable		 1rxcD-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 7 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 1.03A 1rxcF-1g0yR:
undetectable		 1rxcF-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 8 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.95A 1rxcI-1g0yR:
undetectable		 1rxcI-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 8 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.96A 1rxcK-1g0yR:
undetectable		 1rxcK-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 7 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.98A 1rxcL-1g0yR:
undetectable		 1rxcL-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 6 ILE R  14
GLU R  11
LYS R  12
ASN R 216
 None
 1.40A 3kp6A-1g0yR:
undetectable
3kp6B-1g0yR:
0.0		 3kp6A-1g0yR:
19.87
3kp6B-1g0yR:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 6 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.99A 3kvvA-1g0yR:
undetectable		 3kvvA-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 6 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.95A 3kvvB-1g0yR:
undetectable		 3kvvB-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 6 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.96A 3kvvC-1g0yR:
undetectable		 3kvvC-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 6 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.91A 3kvvD-1g0yR:
undetectable		 3kvvD-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 6 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.97A 3kvvE-1g0yR:
undetectable		 3kvvE-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 6 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 1.00A 3kvvF-1g0yR:
undetectable		 3kvvF-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 4 PRO R 206
LEU R 201
ILE R 199
ARG R 174
 None
 1.43A 3w1wA-1g0yR:
undetectable		 3w1wA-1g0yR:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 7 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.96A 4e1vB-1g0yR:
undetectable		 4e1vB-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 8 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.98A 4e1vC-1g0yR:
undetectable		 4e1vC-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 8 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.98A 4e1vD-1g0yR:
undetectable		 4e1vD-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 8 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.98A 4e1vE-1g0yR:
undetectable		 4e1vE-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 1g0y INTERLEUKIN-1
RECEPTOR, TYPE I
(Homo
sapiens) 		4 / 8 GLY R 121
GLN R 113
ILE R 165
VAL R 166
 None
 0.99A 4e1vH-1g0yR:
undetectable		 4e1vH-1g0yR:
23.75