SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 1g1c IMMUNOGLOBULIN-LIKE
DOMAIN I1 FROM TITIN
(Homo
sapiens) 		4 / 8 ILE A   8
TRP A  39
SER A  90
ILE A  12
 None
 1.10A 3sfeB-1g1cA:
0.0
3sfeC-1g1cA:
undetectable		 3sfeB-1g1cA:
19.56
3sfeC-1g1cA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1g1c IMMUNOGLOBULIN-LIKE
DOMAIN I1 FROM TITIN
(Homo
sapiens) 		4 / 6 GLY A  71
THR A  70
SER A  74
VAL A  96
 None
 1.15A 5ewuA-1g1cA:
undetectable		 5ewuA-1g1cA:
17.69