SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g1k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1g1k SCAFFOLDING PROTEIN
([Clostridium]
cellulolyticum) 		3 / 3 LYS A 101
ILE A  98
THR A 111
 None
 0.86A 4gh8A-1g1kA:
undetectable		 4gh8A-1g1kA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1g1k SCAFFOLDING PROTEIN
([Clostridium]
cellulolyticum) 		5 / 12 ASP A  54
VAL A  53
VAL A  59
PHE A  77
ALA A  70
 None
 1.26A 4nc3A-1g1kA:
undetectable		 4nc3A-1g1kA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1g1k SCAFFOLDING PROTEIN
([Clostridium]
cellulolyticum) 		5 / 12 GLY A  42
VAL A 139
THR A 140
ALA A  45
LEU A  48
 None
 1.01A 5kocA-1g1kA:
undetectable		 5kocA-1g1kA:
18.18