SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		5 / 10 ALA 1 250
ILE 1 286
GLY 1 288
ILE 1 289
VAL 1 333
 None
 1.12A 1d4yA-1g291:
undetectable		 1d4yA-1g291:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		4 / 5 ALA 1 124
TYR 1  99
ILE 1 102
ASP 1 117
 None
 1.14A 1upfA-1g291:
undetectable		 1upfA-1g291:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		4 / 5 ALA 1 124
TYR 1  99
ILE 1 102
ASP 1 117
 None
 0.89A 1upfC-1g291:
undetectable		 1upfC-1g291:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		3 / 3 GLN 1  59
ILE 1  60
TYR 1  61
 MG  1 384 (-4.4A)
None
None
 0.64A 1vifA-1g291:
0.0		 1vifA-1g291:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		5 / 12 GLY 1  41
LEU 1   6
VAL 1   4
ALA 1  18
GLY 1  51
 POP  1 501 (-3.1A)
None
None
None
None
 0.97A 2vmyA-1g291:
undetectable		 2vmyA-1g291:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		4 / 5 ILE 1 194
MET 1 213
LEU 1   6
LEU 1  24
 None
 0.85A 2zb7A-1g291:
undetectable		 2zb7A-1g291:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		3 / 3 GLY 1  39
GLY 1  41
THR 1  43
 POP  1 501 (-3.2A)
POP  1 501 (-3.1A)
POP  1 501 ( 4.1A)
 0.44A 3si7B-1g291:
15.6		 3si7B-1g291:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		3 / 3 HIS 1  95
VAL 1 148
LEU 1  92
 None
 0.66A 4m2vA-1g291:
undetectable		 4m2vA-1g291:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		4 / 6 MET 1 213
ILE 1  62
ILE 1  83
VAL 1 160
 None
 0.94A 4olmA-1g291:
0.0		 4olmA-1g291:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		4 / 5 THR 1 366
THR 1 367
ASP 1 364
TYR 1 280
 None
 1.23A 4oltB-1g291:
0.0		 4oltB-1g291:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		3 / 3 PRO 1  94
MET 1  96
TYR 1  93
 None
 0.89A 4qa2B-1g291:
undetectable		 4qa2B-1g291:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		4 / 6 VAL 1  86
LEU 1 127
ILE 1 154
ALA 1 153
 None
 0.79A 4zf8A-1g291:
0.0		 4zf8A-1g291:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		4 / 6 PHE 1 355
PHE 1 339
GLU 1 315
VAL 1 314
 None
 1.21A 5h4dA-1g291:
undetectable		 5h4dA-1g291:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 1g29 MALTOSE TRANSPORT
PROTEIN MALK
(Thermococcus
litoralis) 		5 / 11 ARG 1 327
ASP 1 249
ILE 1 286
GLY 1 288
ILE 1 289
 None
 1.20A 5kr2B-1g291:
undetectable		 5kr2B-1g291:
14.79