SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g2p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.91A 1p7lD-1g2pA:
undetectable		 1p7lD-1g2pA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.89A 1p7lC-1g2pA:
undetectable		 1p7lC-1g2pA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.92A 1rg9B-1g2pA:
undetectable		 1rg9B-1g2pA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.91A 1rg9A-1g2pA:
undetectable		 1rg9A-1g2pA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.91A 1rg9D-1g2pA:
undetectable		 1rg9D-1g2pA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.89A 1rg9C-1g2pA:
undetectable		 1rg9C-1g2pA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 152
GLN A 147
ILE A 127
ALA A 140
LEU A  66
 None
 1.20A 2q72A-1g2pA:
undetectable		 2q72A-1g2pA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 136
TYR A 155
LEU A 152
GLU A 146
VAL A 145
 SO4  A 301 (-3.8A)
None
None
None
None
 1.20A 2vqyA-1g2pA:
0.0		 2vqyA-1g2pA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  81
ILE A  60
LEU A  51
LEU A  77
 None
 0.72A 2xfhA-1g2pA:
undetectable		 2xfhA-1g2pA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 157
GLY A 136
PHE A 175
PHE A  47
 None
SO4  A 301 (-3.8A)
None
None
 1.12A 3ko0R-1g2pA:
undetectable
3ko0T-1g2pA:
undetectable		 3ko0R-1g2pA:
20.86
3ko0T-1g2pA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 142
ILE A 126
VAL A 125
 None
 0.40A 3nv6A-1g2pA:
undetectable		 3nv6A-1g2pA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 HIS A  50
LEU A  51
ASN A 156
ILE A  63
 None
 1.00A 4k0bA-1g2pA:
0.0		 4k0bA-1g2pA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A  89
LYS A  90
LYS A  93
 None
SO4  A 302 (-3.6A)
None
 1.35A 4k50A-1g2pA:
undetectable		 4k50A-1g2pA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A  89
LYS A  90
LYS A  93
 None
SO4  A 302 (-3.6A)
None
 1.35A 4k50E-1g2pA:
0.4		 4k50E-1g2pA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.84A 4kttB-1g2pA:
undetectable		 4kttB-1g2pA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.85A 4kttD-1g2pA:
undetectable		 4kttD-1g2pA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 HIS A  50
LEU A  51
ASN A 156
ILE A  63
 None
 1.00A 4l7iA-1g2pA:
0.0		 4l7iA-1g2pA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.85A 4ndnB-1g2pA:
undetectable		 4ndnB-1g2pA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.87A 4ndnD-1g2pA:
undetectable		 4ndnD-1g2pA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 161
LEU A 164
GLY A 166
LEU A 170
THR A 176
 None
 1.19A 4olmA-1g2pA:
undetectable		 4olmA-1g2pA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.84A 5t8sA-1g2pA:
undetectable		 5t8sA-1g2pA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1g2p ADENINE
PHOSPHORIBOSYLTRANSF
ERASE 1
(Saccharomyces
cerevisiae) 		4 / 7 ALA A  54
ASP A  61
ILE A  60
ILE A  63
 None
 0.87A 6fbnA-1g2pA:
undetectable		 6fbnA-1g2pA:
20.41