SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 5 SER A 103
PHE A  47
GLU A 100
GLY A  98
 None
None
None
SO4  A 200 (-3.0A)
 1.22A 1icrA-1g33A:
undetectable
1icrB-1g33A:
undetectable		 1icrA-1g33A:
15.67
1icrB-1g33A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 5 GLU A 100
GLY A  98
SER A 103
PHE A  47
 None
SO4  A 200 (-3.0A)
None
None
 1.20A 1icrA-1g33A:
undetectable
1icrB-1g33A:
undetectable		 1icrA-1g33A:
15.67
1icrB-1g33A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 6 SER A 103
PHE A  47
GLU A 100
GLY A  98
 None
None
None
SO4  A 200 (-3.0A)
 1.15A 1icuA-1g33A:
undetectable
1icuB-1g33A:
undetectable		 1icuA-1g33A:
15.67
1icuB-1g33A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_A_NIOA704_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 4 SER A 103
PHE A  47
GLU A 100
GLY A  98
 None
None
None
SO4  A 200 (-3.0A)
 1.26A 1icvA-1g33A:
undetectable
1icvB-1g33A:
undetectable		 1icvA-1g33A:
15.67
1icvB-1g33A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 5 SER A 103
PHE A  47
GLU A 100
GLY A  98
 None
None
None
SO4  A 200 (-3.0A)
 1.22A 1icvC-1g33A:
undetectable
1icvD-1g33A:
undetectable		 1icvC-1g33A:
15.67
1icvD-1g33A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 5 GLU A 100
GLY A  98
SER A 103
PHE A  47
 None
SO4  A 200 (-3.0A)
None
None
 1.24A 1icvC-1g33A:
undetectable
1icvD-1g33A:
undetectable		 1icvC-1g33A:
15.67
1icvD-1g33A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 6 SER A 103
PHE A  47
GLU A 100
GLY A  98
 None
None
None
SO4  A 200 (-3.0A)
 1.14A 1kqbA-1g33A:
undetectable
1kqbB-1g33A:
undetectable		 1kqbA-1g33A:
16.13
1kqbB-1g33A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 5 GLU A 100
GLY A  98
SER A 103
PHE A  47
 None
SO4  A 200 (-3.0A)
None
None
 1.13A 1kqbA-1g33A:
undetectable
1kqbB-1g33A:
undetectable		 1kqbA-1g33A:
16.13
1kqbB-1g33A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 6 GLU A 100
GLY A  98
SER A 103
PHE A  47
 None
SO4  A 200 (-3.0A)
None
None
 1.17A 1kqbC-1g33A:
undetectable
1kqbD-1g33A:
undetectable		 1kqbC-1g33A:
16.13
1kqbD-1g33A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		3 / 3 SER A  65
ASP A  76
ASP A  61
 None
 0.63A 3iv6A-1g33A:
undetectable		 3iv6A-1g33A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		3 / 3 SER A  65
ASP A  76
ASP A  61
 None
 0.67A 3iv6C-1g33A:
undetectable		 3iv6C-1g33A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 8 ILE A  66
GLY A  69
PHE A  70
SER A 109
 None
 0.85A 4acbB-1g33A:
undetectable
4acbC-1g33A:
undetectable		 4acbB-1g33A:
11.21
4acbC-1g33A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		5 / 11 ASP A  42
VAL A 106
ALA A 107
PHE A 102
SER A  39
 None
 1.29A 4mm9A-1g33A:
undetectable		 4mm9A-1g33A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1g33 PARVALBUMIN ALPHA
(Rattus
norvegicus) 		4 / 4 PHE A  57
ASP A  51
GLY A  98
SER A  55
 None
CA  A 110 (-3.2A)
SO4  A 200 (-3.0A)
CA  A 110 (-2.5A)
 1.38A 4xp9C-1g33A:
undetectable		 4xp9C-1g33A:
7.76