SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		3 / 4 VAL A 134
TRP A 263
TRP A 171
 None
 1.34A 1gmkC-1g3mA:
undetectable
1gmkD-1g3mA:
undetectable		 1gmkC-1g3mA:
4.38
1gmkD-1g3mA:
4.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_A_LDPA297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 9 PHE A  23
PRO A  46
PHE A  80
LYS A 105
HIS A 107
 PCQ  A 712 ( 4.6A)
PCQ  A 712 ( 4.3A)
PCQ  A 712 (-4.6A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
 0.63A 2a3rA-1g3mA:
43.2		 2a3rA-1g3mA:
49.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_A_LDPA297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 9 PRO A  46
PHE A  80
LYS A 105
HIS A 107
HIS A 148
 PCQ  A 712 ( 4.3A)
PCQ  A 712 (-4.6A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
None
 0.62A 2a3rA-1g3mA:
43.2		 2a3rA-1g3mA:
49.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_B_LDPB297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 9 PHE A  23
PRO A  46
PHE A  80
LYS A 105
HIS A 107
 PCQ  A 712 ( 4.6A)
PCQ  A 712 ( 4.3A)
PCQ  A 712 (-4.6A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
 0.62A 2a3rB-1g3mA:
43.3		 2a3rB-1g3mA:
49.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_B_LDPB297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 9 PRO A  46
PHE A  80
LYS A 105
HIS A 107
HIS A 148
 PCQ  A 712 ( 4.3A)
PCQ  A 712 (-4.6A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
None
 0.62A 2a3rB-1g3mA:
43.3		 2a3rB-1g3mA:
49.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		7 / 10 PHE A  23
PRO A  46
LYS A  47
LYS A 105
HIS A 107
PHE A 141
MET A 247
 PCQ  A 712 ( 4.6A)
PCQ  A 712 ( 4.3A)
A3P  A 701 (-2.7A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.7A)
None
 0.62A 2d06A-1g3mA:
43.3		 2d06A-1g3mA:
50.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		7 / 10 PHE A  23
PRO A  46
LYS A 105
HIS A 107
PHE A 141
TYR A 239
MET A 247
 PCQ  A 712 ( 4.6A)
PCQ  A 712 ( 4.3A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.7A)
PCQ  A 712 ( 4.6A)
None
 0.62A 2d06B-1g3mA:
43.1		 2d06B-1g3mA:
50.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 8 HIS A 224
VAL A 203
ILE A 223
VAL A 219
LEU A 218
 None
 1.29A 3kp6A-1g3mA:
undetectable
3kp6B-1g3mA:
undetectable		 3kp6A-1g3mA:
20.21
3kp6B-1g3mA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 10 ILE A  74
THR A  51
TRP A  52
ILE A 103
ILE A  42
 None
A3P  A 701 (-3.6A)
A3P  A 701 (-3.4A)
None
None
 1.46A 3kpbD-1g3mA:
undetectable		 3kpbD-1g3mA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 12 PRO A 151
LYS A  47
VAL A 134
TYR A 139
PHE A 161
 None
A3P  A 701 (-2.7A)
None
None
None
 1.39A 3meeA-1g3mA:
undetectable		 3meeA-1g3mA:
19.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		8 / 9 TYR A  20
PHE A  80
CYH A  83
LYS A 105
HIS A 107
PHE A 141
ILE A 246
MET A 247
 PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.6A)
None
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.7A)
PCQ  A 712 (-4.3A)
None
 0.24A 4jvlA-1g3mA:
50.3		 4jvlA-1g3mA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_B_ESTB302_1
(ESTROGEN
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		8 / 9 TYR A  20
PHE A  80
CYH A  83
LYS A 105
HIS A 107
PHE A 141
ILE A 246
MET A 247
 PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.6A)
None
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.7A)
PCQ  A 712 (-4.3A)
None
 0.24A 4jvlB-1g3mA:
49.3		 4jvlB-1g3mA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		3 / 3 ASP A 121
TRP A 178
SER A 184
 None
 1.01A 4lrhB-1g3mA:
0.0		 4lrhB-1g3mA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		3 / 3 ASP A 121
TRP A 178
SER A 184
 None
 0.96A 4lrhF-1g3mA:
undetectable		 4lrhF-1g3mA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		4 / 4 ASN A 130
VAL A 136
THR A 260
ILE A 259
 None
 1.48A 4retA-1g3mA:
0.0		 4retA-1g3mA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		4 / 4 ASN A 130
VAL A 136
THR A 260
ILE A 259
 None
 1.48A 4retC-1g3mA:
0.0		 4retC-1g3mA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		4 / 6 GLU A 202
LEU A 195
LEU A 188
LEU A 206
 None
 1.16A 5yvnA-1g3mA:
1.5		 5yvnA-1g3mA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		3 / 3 ALA A 135
VAL A 175
TYR A  45
 None
 0.71A 5zmqH-1g3mA:
0.0		 5zmqH-1g3mA:
19.30