SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g3n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		5 / 11 LEU C  79
LEU C  76
ALA C  75
LEU C 101
LEU C 138
 None
 1.23A 1g50A-1g3nC:
undetectable		 1g50A-1g3nC:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		5 / 10 LEU C  79
LEU C  76
ALA C  75
LEU C 101
LEU C 138
 None
 1.09A 1gwrA-1g3nC:
0.0		 1gwrA-1g3nC:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		5 / 12 ALA C 200
ALA C 199
LEU C 228
ALA C 238
LEU C 162
 None
 1.06A 1xiuB-1g3nC:
undetectable		 1xiuB-1g3nC:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		3 / 3 GLN C 223
LYS C 161
VAL C 163
 None
 0.91A 2jfaB-1g3nC:
1.8		 2jfaB-1g3nC:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		5 / 10 VAL C 206
ILE C 197
LEU C 224
VAL C 220
LEU C 162
 None
 1.05A 3gwxA-1g3nC:
0.0		 3gwxA-1g3nC:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		5 / 12 ILE C 196
ALA C 194
GLU C  29
LEU C  26
ILE C 227
 None
 1.17A 3ia4D-1g3nC:
undetectable		 3ia4D-1g3nC:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		4 / 7 ILE C 196
SER C 198
PHE C  22
LEU C 158
 None
 0.74A 3v7pA-1g3nC:
undetectable		 3v7pA-1g3nC:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		5 / 12 LEU C  79
LEU C  76
ALA C  75
LEU C 101
LEU C 138
 None
 1.13A 4pxmA-1g3nC:
1.9		 4pxmA-1g3nC:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		4 / 6 LEU C 192
ALA C 200
SER C 195
VAL C 221
 None
 1.21A 5a6iA-1g3nC:
undetectable		 5a6iA-1g3nC:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		4 / 6 GLY C  55
THR C  56
VAL C 185
HIS C  49
 None
 0.86A 5ewuA-1g3nC:
undetectable		 5ewuA-1g3nC:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		4 / 6 PRO C 187
GLU C  91
ALA C  99
LEU C 138
 None
 1.02A 5igiA-1g3nC:
undetectable		 5igiA-1g3nC:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		5 / 12 ALA C 200
ALA C 199
LEU C 228
ALA C 238
LEU C 162
 None
 1.00A 6a60D-1g3nC:
undetectable		 6a60D-1g3nC:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		3 / 3 SER C 105
LYS C 106
SER C 109
 None
 0.60A 6az3P-1g3nC:
undetectable		 6az3P-1g3nC:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		5 / 12 SER C 245
ASN C  77
LEU C 150
GLY C 190
ASP C  80
 None
 1.38A 6dwnA-1g3nC:
0.0		 6dwnA-1g3nC:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1g3n V-CYCLIN
(Human
gammaherpesvirus
8) 		3 / 3 VAL C 221
ALA C 203
GLN C 236
 None
 0.46A 6gb9A-1g3nC:
undetectable		 6gb9A-1g3nC:
19.83