SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1g5q EPIDERMIN MODIFYING
ENZYME EPID
(Staphylococcus
epidermidis) 		4 / 8 VAL A  79
LEU A  99
PRO A  81
SER A  40
 None
 0.98A 1jtvA-1g5qA:
6.1		 1jtvA-1g5qA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 1g5q EPIDERMIN MODIFYING
ENZYME EPID
(Staphylococcus
epidermidis) 		5 / 9 LEU A  25
VAL A  32
LEU A  80
ILE A   7
PHE A 113
 None
 1.15A 3tbgD-1g5qA:
0.0		 3tbgD-1g5qA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1g5q EPIDERMIN MODIFYING
ENZYME EPID
(Staphylococcus
epidermidis) 		4 / 5 SER A  37
THR A  10
GLU A  59
ASP A  62
 FMN  A 300 (-2.8A)
FMN  A 300 (-4.0A)
None
None
 1.28A 3tm4B-1g5qA:
3.8		 3tm4B-1g5qA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1g5q EPIDERMIN MODIFYING
ENZYME EPID
(Staphylococcus
epidermidis) 		3 / 3 LEU A   5
ASP A  54
ILE A 165
 None
 0.67A 4xi3D-1g5qA:
undetectable		 4xi3D-1g5qA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1g5q EPIDERMIN MODIFYING
ENZYME EPID
(Staphylococcus
epidermidis) 		5 / 12 GLY A 106
ILE A  70
THR A 105
ILE A  68
GLY A  93
 None
 0.93A 5d4uC-1g5qA:
3.3		 5d4uC-1g5qA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1g5q EPIDERMIN MODIFYING
ENZYME EPID
(Staphylococcus
epidermidis) 		5 / 12 GLY A 106
ILE A  70
THR A 105
ILE A  68
GLY A  93
 None
 0.99A 5d4uD-1g5qA:
3.6		 5d4uD-1g5qA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 1g5q EPIDERMIN MODIFYING
ENZYME EPID
(Staphylococcus
epidermidis) 		4 / 6 LEU A 110
LEU A  99
THR A  10
ASN A  85
 None
None
FMN  A 300 (-4.0A)
FMN  A 300 (-3.9A)
 0.95A 6f88B-1g5qA:
0.0		 6f88B-1g5qA:
15.56