SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)
1g5z OUTER SURFACE
PROTEIN C

(Borreliella
burgdorferi)
4 / 5 LEU A 137
ILE A  69
ILE A 103
ALA A 102
None
0.70A 2i2zA-1g5zA:
undetectable
2i2zA-1g5zA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)
1g5z OUTER SURFACE
PROTEIN C

(Borreliella
burgdorferi)
4 / 4 LEU A 137
ILE A  69
ILE A 103
ALA A 102
None
0.62A 2i30A-1g5zA:
undetectable
2i30A-1g5zA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
1g5z OUTER SURFACE
PROTEIN C

(Borreliella
burgdorferi)
6 / 9 LEU A  96
ILE A  77
GLY A  78
LEU A  97
LEU A 149
ALA A 154
None
1.24A 5o96A-1g5zA:
undetectable
5o96B-1g5zA:
undetectable
5o96A-1g5zA:
22.98
5o96B-1g5zA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1g5z OUTER SURFACE
PROTEIN C

(Borreliella
burgdorferi)
5 / 7 GLY A 168
LEU A 172
LEU A 106
ILE A 158
LEU A  97
None
1.37A 5vkqA-1g5zA:
3.6
5vkqB-1g5zA:
6.3
5vkqA-1g5zA:
6.97
5vkqB-1g5zA:
6.97