SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g60'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		12 / 12 ASN A  11
CYH A  12
ASP A  30
TRP A  40
PRO A 196
PHE A 220
GLY A 222
SER A 223
THR A 225
MET A 242
ASN A 243
TYR A 246
 SAM  A 500 (-4.1A)
SAM  A 500 (-3.4A)
SAM  A 500 (-3.7A)
SAM  A 500 (-3.8A)
SAM  A 500 (-4.0A)
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
SAM  A 500 (-3.4A)
SAM  A 500 (-3.6A)
None
SAM  A 500 (-4.4A)
 0.00A 1g60A-1g60A:
41.1		 1g60A-1g60A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		6 / 12 ASP A  30
TRP A  40
GLY A 222
THR A 226
MET A 242
ASN A 243
 SAM  A 500 (-3.7A)
SAM  A 500 (-3.8A)
SAM  A 500 (-3.2A)
None
SAM  A 500 (-3.6A)
None
 1.47A 1g60A-1g60A:
41.1		 1g60A-1g60A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 CYH A 219
TRP A  40
PHE A 220
ASN A 243
TYR A 246
 None
SAM  A 500 (-3.8A)
SAM  A 500 (-4.6A)
None
SAM  A 500 (-4.4A)
 1.46A 1g60A-1g60A:
41.1		 1g60A-1g60A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		11 / 12 ASN A  11
CYH A  12
ASP A  30
TRP A  40
PRO A 196
PHE A 220
GLY A 222
THR A 225
MET A 242
ASN A 243
TYR A 246
 SAM  A 500 (-4.1A)
SAM  A 500 (-3.4A)
SAM  A 500 (-3.7A)
SAM  A 500 (-3.8A)
SAM  A 500 (-4.0A)
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
SAM  A 500 (-3.6A)
None
SAM  A 500 (-4.4A)
 0.13A 1g60B-1g60A:
38.3		 1g60B-1g60A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		6 / 12 ASP A  30
TRP A  40
GLY A 222
THR A 226
MET A 242
ASN A 243
 SAM  A 500 (-3.7A)
SAM  A 500 (-3.8A)
SAM  A 500 (-3.2A)
None
SAM  A 500 (-3.6A)
None
 1.47A 1g60B-1g60A:
38.3		 1g60B-1g60A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 CYH A 219
TRP A  40
PHE A 220
ASN A 243
TYR A 246
 None
SAM  A 500 (-3.8A)
SAM  A 500 (-4.6A)
None
SAM  A 500 (-4.4A)
 1.42A 1g60B-1g60A:
38.3		 1g60B-1g60A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		6 / 12 CYH A  12
PRO A  32
LYS A 197
PHE A 220
GLY A 222
SER A 223
 SAM  A 500 (-3.4A)
None
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
 0.51A 1nw5A-1g60A:
25.2		 1nw5A-1g60A:
32.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		4 / 8 TRP A  96
LEU A  86
PHE A  93
TYR A  54
 None
 0.71A 1rtsA-1g60A:
0.0		 1rtsA-1g60A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		6 / 11 LEU A 215
ALA A 230
VAL A  28
GLY A 224
ILE A   7
VAL A 216
 None
 1.43A 1t7jA-1g60A:
undetectable		 1t7jA-1g60A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 ILE A 205
ILE A  97
THR A 118
PHE A  93
LEU A  86
 None
 1.16A 2qo5A-1g60A:
undetectable		 2qo5A-1g60A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		4 / 8 TRP A  96
LEU A  86
PHE A  93
TYR A  54
 None
 0.79A 2tsrB-1g60A:
undetectable		 2tsrB-1g60A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 PHE A 220
GLY A 222
MET A 242
CYH A  12
PRO A  32
 SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.6A)
SAM  A 500 (-3.4A)
None
 0.95A 3av6A-1g60A:
5.5		 3av6A-1g60A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		3 / 3 GLY A 222
GLY A 224
THR A 226
 SAM  A 500 (-3.2A)
None
None
 0.36A 3si7B-1g60A:
0.2		 3si7B-1g60A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 9 LEU A 215
ALA A 230
VAL A  28
GLY A 224
ILE A   7
 None
 1.33A 3spkA-1g60A:
undetectable		 3spkA-1g60A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA802_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 9 PHE A 220
ASP A 241
MET A 242
TYR A 246
PRO A  32
 SAM  A 500 (-4.6A)
SAM  A 500 (-2.9A)
SAM  A 500 (-3.6A)
SAM  A 500 (-4.4A)
None
 0.50A 3v8vA-1g60A:
3.9		 3v8vA-1g60A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA802_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 9 PHE A 220
MET A 242
TYR A 246
CYH A  12
PRO A  32
 SAM  A 500 (-4.6A)
SAM  A 500 (-3.6A)
SAM  A 500 (-4.4A)
SAM  A 500 (-3.4A)
None
 1.29A 3v8vA-1g60A:
3.9		 3v8vA-1g60A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB802_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		6 / 12 PHE A 220
MET A 242
TYR A 246
CYH A  12
ASP A  30
PRO A  32
 SAM  A 500 (-4.6A)
SAM  A 500 (-3.6A)
SAM  A 500 (-4.4A)
SAM  A 500 (-3.4A)
SAM  A 500 (-3.7A)
None
 1.34A 3v8vB-1g60A:
5.1		 3v8vB-1g60A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		4 / 7 PHE A  73
VAL A  28
ILE A 206
GLU A 117
 None
 1.09A 4a97E-1g60A:
undetectable		 4a97E-1g60A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 PHE A 220
GLY A 222
ASN A 243
PRO A  32
TYR A  33
 SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
None
None
None
 0.65A 4rtmA-1g60A:
2.0		 4rtmA-1g60A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 PHE A 220
GLY A 222
ASN A 243
ASP A  30
PRO A  32
 SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
None
SAM  A 500 (-3.7A)
None
 0.85A 4rtpA-1g60A:
undetectable		 4rtpA-1g60A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		6 / 11 PHE A 220
ASP A 241
ASN A 243
ASP A  30
PRO A  32
TYR A  33
 SAM  A 500 (-4.6A)
SAM  A 500 (-2.9A)
None
SAM  A 500 (-3.7A)
None
None
 0.86A 4rtrA-1g60A:
3.2		 4rtrA-1g60A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		7 / 12 PHE A 220
GLY A 222
ASP A 241
ASN A 243
ASP A  30
PRO A  32
TYR A  33
 SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.9A)
None
SAM  A 500 (-3.7A)
None
None
 0.91A 4rtsA-1g60A:
2.2		 4rtsA-1g60A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 ASP A  30
PHE A 220
GLY A 222
THR A 225
TYR A 246
 SAM  A 500 (-3.7A)
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 0.44A 5hfjA-1g60A:
22.9		 5hfjA-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 ASP A  30
PRO A  32
PHE A 220
GLY A 222
THR A 225
 SAM  A 500 (-3.7A)
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
 0.65A 5hfjA-1g60A:
22.9		 5hfjA-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 ASP A  30
PHE A 220
GLY A 222
THR A 225
TYR A 246
 SAM  A 500 (-3.7A)
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 0.60A 5hfjB-1g60A:
23.0		 5hfjB-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 ASP A  30
PRO A  32
PHE A 220
GLY A 222
THR A 225
 SAM  A 500 (-3.7A)
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
 0.72A 5hfjB-1g60A:
23.0		 5hfjB-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 PHE A 220
GLY A 222
SER A 223
THR A 225
TYR A 246
 SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 0.76A 5hfjB-1g60A:
23.0		 5hfjB-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 PRO A  32
PHE A 220
GLY A 222
SER A 223
THR A 225
 None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
SAM  A 500 (-3.4A)
 0.80A 5hfjB-1g60A:
23.0		 5hfjB-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 LYS A 197
PHE A 220
GLY A 222
THR A 225
TYR A 246
 None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 0.51A 5hfjC-1g60A:
23.4		 5hfjC-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 PRO A  32
LYS A 197
PHE A 220
GLY A 222
THR A 225
 None
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
 0.67A 5hfjC-1g60A:
23.4		 5hfjC-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 THR A 195
LYS A 197
GLY A 222
THR A 225
TYR A 246
 None
None
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 1.07A 5hfjC-1g60A:
23.4		 5hfjC-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 ASP A  30
PHE A 220
GLY A 222
SER A 223
TYR A 246
 SAM  A 500 (-3.7A)
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
SAM  A 500 (-4.4A)
 0.70A 5hfjD-1g60A:
23.4		 5hfjD-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 ASP A  30
PRO A  32
PHE A 220
GLY A 222
SER A 223
 SAM  A 500 (-3.7A)
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
 0.65A 5hfjD-1g60A:
23.4		 5hfjD-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 PHE A 220
GLY A 222
SER A 223
THR A 225
TYR A 246
 SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 0.56A 5hfjD-1g60A:
23.4		 5hfjD-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		5 / 12 PRO A  32
PHE A 220
GLY A 222
SER A 223
THR A 225
 None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
SAM  A 500 (-3.4A)
 0.61A 5hfjD-1g60A:
23.4		 5hfjD-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		7 / 12 ASP A  30
LYS A 197
PHE A 220
GLY A 222
SER A 223
THR A 225
TYR A 246
 SAM  A 500 (-3.7A)
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-2.8A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 0.69A 5hfjE-1g60A:
23.4		 5hfjE-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		7 / 12 ASP A  30
PRO A  32
LYS A 197
PHE A 220
GLY A 222
THR A 225
TYR A 246
 SAM  A 500 (-3.7A)
None
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 0.79A 5hfjG-1g60A:
22.9		 5hfjG-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		6 / 12 ASP A  30
LYS A 197
PHE A 220
GLY A 222
THR A 225
TYR A 246
 SAM  A 500 (-3.7A)
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
SAM  A 500 (-4.4A)
 0.68A 5hfjH-1g60A:
23.1		 5hfjH-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		6 / 12 ASP A  30
PRO A  32
LYS A 197
PHE A 220
GLY A 222
THR A 225
 SAM  A 500 (-3.7A)
None
None
SAM  A 500 (-4.6A)
SAM  A 500 (-3.2A)
SAM  A 500 (-3.4A)
 0.66A 5hfjH-1g60A:
23.1		 5hfjH-1g60A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		3 / 3 GLY A 222
ASP A 241
ASN A  11
 SAM  A 500 (-3.2A)
SAM  A 500 (-2.9A)
SAM  A 500 (-4.1A)
 0.35A 5jglA-1g60A:
3.8		 5jglA-1g60A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1g60 ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA
(Moraxella
bovis) 		3 / 3 ASP A 241
ASN A  11
PHE A  73
 SAM  A 500 (-2.9A)
SAM  A 500 (-4.1A)
None
 0.92A 5jglB-1g60A:
3.0		 5jglB-1g60A:
20.51