SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
SER A 235
GLY A 236
ARG A 244
 SO4  A 400 (-2.9A)
SO4  A 400 ( 4.7A)
SO4  A 400 (-2.7A)
None
SO4  A 400 (-3.5A)
SO4  A 400 (-3.0A)
SO4  A 400 ( 4.6A)
 0.48A 1ghmA-1g68A:
35.5		 1ghmA-1g68A:
35.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 8 ALA A 248
GLY A 283
ILE A 286
PRO A 226
ILE A 231
 None
 1.17A 1hshD-1g68A:
undetectable		 1hshD-1g68A:
17.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
GLY A 236
ALA A 237
 SO4  A 400 (-2.9A)
SO4  A 400 ( 4.7A)
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
 0.56A 1i2wA-1g68A:
38.2		 1i2wA-1g68A:
32.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 105
PRO A 167
LEU A 169
ARG A 244
 None
None
None
SO4  A 400 ( 4.6A)
 0.62A 1i2wA-1g68A:
38.2		 1i2wA-1g68A:
32.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
GLY A 236
ALA A 237
ARG A 244
 SO4  A 400 (-2.9A)
SO4  A 400 ( 4.7A)
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.54A 1i2wB-1g68A:
38.4		 1i2wB-1g68A:
32.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 6 ALA A  76
LYS A  79
ASP A  83
ALA A  84
 None
 0.27A 1iwhA-1g68A:
undetectable		 1iwhA-1g68A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 8 ILE A 263
LEU A 265
GLU A  37
VAL A  33
ILE A 282
 None
 1.46A 1linA-1g68A:
undetectable		 1linA-1g68A:
18.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 (-2.9A)
SO4  A 400 ( 4.7A)
SO4  A 400 (-2.7A)
None
None
None
SO4  A 400 (-3.0A)
None
 0.56A 1ymxA-1g68A:
39.6		 1ymxA-1g68A:
39.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 (-2.9A)
SO4  A 400 ( 4.7A)
SO4  A 400 (-2.7A)
None
None
None
SO4  A 400 (-3.0A)
None
 0.52A 1ymxB-1g68A:
39.8		 1ymxB-1g68A:
39.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 8 GLY A 172
GLY A 242
THR A 268
ALA A 266
ALA A 243
 None
 1.45A 2ej3C-1g68A:
undetectable		 2ej3C-1g68A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 9 PRO A 145
LEU A 162
LEU A 139
ALA A 135
PHE A  72
 None
 1.11A 2vcvD-1g68A:
0.0		 2vcvD-1g68A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 9 PRO A 145
LEU A 162
LEU A 139
ALA A 135
PHE A  72
 None
 1.07A 2vcvE-1g68A:
0.0		 2vcvE-1g68A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 9 PRO A 145
LEU A 162
LEU A 139
ALA A 135
PHE A  72
 None
 1.07A 2vcvH-1g68A:
undetectable		 2vcvH-1g68A:
23.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		6 / 12 LYS A  73
TYR A 105
ASN A 132
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 ( 4.7A)
None
None
None
SO4  A 400 (-3.0A)
None
 0.63A 3hlwA-1g68A:
39.5		 3hlwA-1g68A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		6 / 12 LYS A  73
TYR A 105
SER A 130
ASN A 132
GLY A 236
GLY A 238
 SO4  A 400 ( 4.7A)
None
SO4  A 400 (-2.7A)
None
SO4  A 400 (-3.0A)
None
 0.65A 3hlwA-1g68A:
39.5		 3hlwA-1g68A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 LYS A  73
ASN A 132
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 ( 4.7A)
None
None
SO4  A 400 (-3.0A)
None
 0.36A 3huoA-1g68A:
39.7		 3huoA-1g68A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 6 THR A  51
GLY A 196
ALA A 257
PRO A 258
 None
 0.45A 3huoA-1g68A:
39.7		 3huoA-1g68A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 LYS A  73
ASN A 132
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 ( 4.7A)
None
None
SO4  A 400 (-3.0A)
None
 0.33A 3huoB-1g68A:
39.6		 3huoB-1g68A:
39.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 8 SER A 106
ASP A 101
VAL A  95
LEU A 119
 None
 1.11A 3jq7C-1g68A:
undetectable		 3jq7C-1g68A:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 9 ILE A 155
LYS A 192
PHE A 195
ALA A  78
LEU A 152
 None
 1.19A 3o01A-1g68A:
0.0
3o01B-1g68A:
0.0		 3o01A-1g68A:
25.99
3o01B-1g68A:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 155
LYS A 192
PHE A 195
ALA A  78
LEU A 152
 None
 1.18A 3o02A-1g68A:
0.0
3o02B-1g68A:
0.0		 3o02A-1g68A:
25.99
3o02B-1g68A:
25.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		6 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 ( 4.7A)
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
None
 0.56A 3q07A-1g68A:
39.6		 3q07A-1g68A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		6 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 ( 4.7A)
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
None
 0.55A 3q07B-1g68A:
37.6		 3q07B-1g68A:
39.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 261
LEU A 190
ASP A 233
MET A 211
 None
 0.92A 3rgfA-1g68A:
0.0		 3rgfA-1g68A:
19.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 12 SER A  70
TYR A 105
SER A 130
ASN A 132
GLY A 236
ALA A 237
ARG A 244
 SO4  A 400 (-2.9A)
None
SO4  A 400 (-2.7A)
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.54A 3sh8A-1g68A:
36.8		 3sh8A-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLY A 236
ALA A 237
ARG A 244
 SO4  A 400 (-2.9A)
SO4  A 400 ( 4.7A)
SO4  A 400 (-2.7A)
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.60A 3sh8B-1g68A:
36.4		 3sh8B-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 10 TYR A 105
SER A 130
ASN A 132
VAL A 216
GLY A 236
ALA A 237
ARG A 244
 None
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.52A 4fh2A-1g68A:
39.8		 4fh2A-1g68A:
45.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 161
ASP A 176
ASP A 163
ARG A 178
 None
 1.35A 4kcnA-1g68A:
undetectable		 4kcnA-1g68A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 161
ASP A 176
ASP A 163
ARG A 178
 None
 1.33A 4kcnB-1g68A:
undetectable		 4kcnB-1g68A:
19.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		8 / 12 SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
GLY A 236
ALA A 237
ARG A 244
 SO4  A 400 (-2.9A)
None
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.52A 4n9kA-1g68A:
38.3		 4n9kA-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
GLY A 236
ALA A 237
ARG A 244
 SO4  A 400 (-2.9A)
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.53A 4n9kB-1g68A:
38.2		 4n9kB-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		6 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
GLY A 236
GLY A 238
 None
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
None
 0.47A 4pm5A-1g68A:
39.4		 4pm5A-1g68A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		8 / 12 LYS A  73
TYR A 105
SER A 130
ASN A 132
ASN A 170
GLY A 236
ALA A 237
GLY A 238
 SO4  A 400 ( 4.7A)
None
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
None
 0.48A 4pm7A-1g68A:
39.4		 4pm7A-1g68A:
39.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
GLY A 236
ALA A 237
GLY A 238
 None
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
None
 0.49A 4pm9A-1g68A:
39.5		 4pm9A-1g68A:
39.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 THR A  69
GLY A 242
GLY A 240
GLY A 172
ALA A 270
 None
 0.82A 4uciA-1g68A:
undetectable		 4uciA-1g68A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 THR A  69
GLY A 242
GLY A 240
GLY A 172
ALA A 270
 None
 0.82A 4uciB-1g68A:
undetectable		 4uciB-1g68A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 THR A  69
GLY A 242
GLY A 240
GLY A 172
ALA A 270
 None
 0.82A 4uckA-1g68A:
undetectable		 4uckA-1g68A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 259
VAL A 289
TYR A 290
VAL A 261
 None
 0.86A 5ecnD-1g68A:
undetectable		 5ecnD-1g68A:
20.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
GLY A 236
ALA A 237
ARG A 244
 SO4  A 400 (-2.9A)
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.59A 5ghyA-1g68A:
38.2		 5ghyA-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		6 / 12 SER A  70
TYR A 105
ASN A 132
ASN A 170
GLY A 236
ARG A 244
 SO4  A 400 (-2.9A)
None
None
None
SO4  A 400 (-3.0A)
SO4  A 400 ( 4.6A)
 1.35A 5ghyA-1g68A:
38.2		 5ghyA-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
GLY A 236
ALA A 237
ARG A 244
 SO4  A 400 (-2.9A)
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.55A 5ghyB-1g68A:
38.3		 5ghyB-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		6 / 12 SER A  70
TYR A 105
ASN A 132
ASN A 170
GLY A 236
ARG A 244
 SO4  A 400 (-2.9A)
None
None
None
SO4  A 400 (-3.0A)
SO4  A 400 ( 4.6A)
 1.30A 5ghyB-1g68A:
38.3		 5ghyB-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		8 / 11 SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
GLY A 236
ALA A 237
ARG A 244
 SO4  A 400 (-2.9A)
None
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 (-3.6A)
SO4  A 400 ( 4.6A)
 0.52A 5ghzA-1g68A:
38.2		 5ghzA-1g68A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		7 / 10 SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
GLY A 236
ARG A 244
 SO4  A 400 (-2.9A)
None
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
SO4  A 400 ( 4.6A)
 0.56A 5ghzB-1g68A:
38.3		 5ghzB-1g68A:
31.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 8 VAL A 142
ILE A 138
ALA A 135
PHE A 151
VAL A 148
 None
 1.30A 5l94A-1g68A:
undetectable		 5l94A-1g68A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 266
THR A 268
ALA A 237
GLY A 238
THR A  69
 None
None
SO4  A 400 (-3.6A)
None
None
 1.22A 5lf3H-1g68A:
undetectable
5lf3I-1g68A:
undetectable		 5lf3H-1g68A:
19.93
5lf3I-1g68A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 266
THR A 268
ALA A 237
GLY A 238
THR A  69
 None
None
SO4  A 400 (-3.6A)
None
None
 1.22A 5lf3V-1g68A:
undetectable
5lf3W-1g68A:
undetectable		 5lf3V-1g68A:
19.93
5lf3W-1g68A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 7 THR A 149
PHE A  72
ASP A 179
LEU A 169
 None
 1.20A 5uxcA-1g68A:
0.0		 5uxcA-1g68A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		4 / 8 PRO A 107
ALA A 122
THR A 126
THR A 129
 None
 0.85A 5x2tI-1g68A:
undetectable
5x2tJ-1g68A:
undetectable
5x2tK-1g68A:
undetectable
5x2tL-1g68A:
undetectable		 5x2tI-1g68A:
21.03
5x2tJ-1g68A:
21.65
5x2tK-1g68A:
21.03
5x2tL-1g68A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 SER A  70
SER A 130
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 (-2.9A)
SO4  A 400 (-2.7A)
None
SO4  A 400 (-3.0A)
None
 0.62A 6b68D-1g68A:
37.1		 6b68D-1g68A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		6 / 12 SER A  70
SER A 130
PRO A 167
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 (-2.9A)
SO4  A 400 (-2.7A)
None
None
SO4  A 400 (-3.0A)
None
 0.62A 6b6cA-1g68A:
37.0		 6b6cA-1g68A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 SER A  70
PRO A 167
ASN A 170
GLY A 236
GLY A 238
 SO4  A 400 (-2.9A)
None
None
SO4  A 400 (-3.0A)
None
 0.26A 6b6fA-1g68A:
36.8		 6b6fA-1g68A:
15.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 105
ASN A 132
ASN A 170
GLY A 236
GLY A 238
 None
None
None
SO4  A 400 (-3.0A)
None
 0.51A 6c79A-1g68A:
39.5		 6c79A-1g68A:
37.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1g68 BETA-LACTAMASE PSE-4
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 105
SER A 130
ASN A 132
GLY A 236
GLY A 238
 None
SO4  A 400 (-2.7A)
None
SO4  A 400 (-3.0A)
None
 0.62A 6c79A-1g68A:
39.5		 6c79A-1g68A:
37.65