SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g6o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 11 PHE A  84
ARG A  29
ALA A 109
LEU A  28
ALA A  31
 None
 1.25A 1jb0B-1g6oA:
undetectable		 1jb0B-1g6oA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		4 / 7 PHE A  84
ILE A  45
ILE A  48
THR A  32
 None
 0.92A 1sbrB-1g6oA:
0.2		 1sbrB-1g6oA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 12 GLY A 167
PHE A 194
VAL A 174
ASP A 166
ALA A 163
 None
 1.38A 2avdB-1g6oA:
3.8		 2avdB-1g6oA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		4 / 8 SER A 190
TYR A 187
TYR A 151
HIS A 142
 None
 1.27A 2bteD-1g6oA:
undetectable		 2bteD-1g6oA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 12 VAL A  56
THR A  32
PHE A  84
ILE A 130
PHE A  36
 None
 0.98A 2v95A-1g6oA:
0.3		 2v95A-1g6oA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 12 VAL A  56
THR A  32
PHE A  84
ILE A 130
PHE A  36
 None
 1.04A 2vdyB-1g6oA:
0.9		 2vdyB-1g6oA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 10 PHE A  84
ARG A  29
ALA A 109
LEU A  28
ALA A  31
 None
 1.13A 2wscB-1g6oA:
undetectable		 2wscB-1g6oA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 10 PHE A  84
ARG A  29
ALA A 109
LEU A  28
ALA A  31
 None
 1.13A 2wseB-1g6oA:
undetectable		 2wseB-1g6oA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 9 PHE A  84
ARG A  29
ALA A 109
LEU A  28
ALA A  31
 None
 1.14A 2wsfB-1g6oA:
0.0		 2wsfB-1g6oA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 12 TYR A 326
PHE A 257
LEU A 261
ALA A 280
SER A 277
 None
 1.36A 3apvA-1g6oA:
0.0		 3apvA-1g6oA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 12 ILE A 164
LEU A 269
ILE A 188
VAL A 314
PHE A 325
 None
 1.11A 3b2rA-1g6oA:
undetectable		 3b2rA-1g6oA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		4 / 6 THR A 270
THR A 268
ILE A 310
LEU A 261
 None
 0.78A 3deuB-1g6oA:
0.0		 3deuB-1g6oA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 10 PHE A  84
ARG A  29
ALA A 109
LEU A  28
ALA A  31
 None
 1.11A 3lw5B-1g6oA:
undetectable		 3lw5B-1g6oA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 11 PHE A  84
ARG A  29
ALA A 109
LEU A  28
ALA A  31
 None
 1.25A 3pcqB-1g6oA:
undetectable		 3pcqB-1g6oA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		3 / 3 GLY A 181
GLY A 183
THR A 185
 ADP  A 401 (-3.2A)
ADP  A 401 (-3.2A)
ADP  A 401 (-3.5A)
 0.43A 3si7B-1g6oA:
5.9		 3si7B-1g6oA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 9 ALA A  31
LEU A  28
PHE A  36
SER A 106
ILE A 130
 None
 1.24A 3tq8A-1g6oA:
undetectable		 3tq8A-1g6oA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 12 GLY A 247
ALA A 274
GLY A 178
GLU A 279
MET A 287
 None
 0.96A 3v3oB-1g6oA:
1.6		 3v3oB-1g6oA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 8 ILE A 168
ASP A 166
ILE A 164
VAL A 314
SER A 277
 None
 1.45A 4ac9C-1g6oA:
2.1		 4ac9C-1g6oA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 10 ALA A  31
LEU A  28
PHE A  36
SER A 106
ILE A 130
 None
 1.27A 4g8zX-1g6oA:
undetectable		 4g8zX-1g6oA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		3 / 3 ARG A  29
LEU A  25
GLU A  22
 None
 0.75A 4l3gF-1g6oA:
0.0		 4l3gF-1g6oA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		4 / 8 PHE A  84
ARG A  29
ALA A 109
LEU A  28
 None
 0.93A 4rkuA-1g6oA:
0.0
4rkuJ-1g6oA:
0.0		 4rkuA-1g6oA:
17.82
4rkuJ-1g6oA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		4 / 7 PHE A  84
ARG A  29
ALA A 109
LEU A  28
 None
 0.94A 4xk8A-1g6oA:
undetectable		 4xk8A-1g6oA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		3 / 3 PHE A  84
ILE A 116
ASP A  97
 None
 0.70A 5cswA-1g6oA:
undetectable		 5cswA-1g6oA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		3 / 3 PHE A  84
ILE A 116
ASP A  97
 None
 0.70A 5cswB-1g6oA:
undetectable		 5cswB-1g6oA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		5 / 12 VAL A  58
THR A  32
PHE A  84
ILE A 130
PHE A  36
 None
 1.09A 5hgcA-1g6oA:
0.6		 5hgcA-1g6oA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		4 / 7 ARG A 238
THR A 219
ILE A 202
LEU A 221
 None
 0.87A 5te8C-1g6oA:
0.1		 5te8C-1g6oA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1g6o CAG-ALPHA
(Helicobacter
pylori) 		4 / 7 SER A 106
LEU A 104
ILE A 128
LEU A 118
 None
 0.80A 5te8C-1g6oA:
0.1		 5te8C-1g6oA:
21.16