SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 11 SER 1 329
GLY 1 334
GLY 1 331
PHE 1 327
ASP 1 301
 None
 1.45A 1ho5A-1g6q1:
undetectable		 1ho5A-1g6q1:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1  64
LEU 1  63
VAL 1  62
ILE 1  61
 None
 0.97A 1s9qA-1g6q1:
undetectable		 1s9qA-1g6q1:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 PRO 1 292
HIS 1 203
PHE 1 137
ILE 1 323
 None
 1.22A 1sbrA-1g6q1:
0.6
1sbrB-1g6q1:
undetectable		 1sbrA-1g6q1:
20.78
1sbrB-1g6q1:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 SER 1 176
ASP 1 296
ASP 1 249
 None
 0.53A 2plwA-1g6q1:
7.0		 2plwA-1g6q1:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 11 LEU 1 138
LEU 1 139
ILE 1 168
PHE 1 237
LEU 1 307
 None
 1.20A 2q6hA-1g6q1:
0.0		 2q6hA-1g6q1:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 11 LEU 1 138
LEU 1 139
ILE 1 168
PHE 1 237
LEU 1 307
 None
 1.16A 2qeiA-1g6q1:
undetectable		 2qeiA-1g6q1:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 10 ILE 1 251
LEU 1 170
ILE 1 303
ILE 1 323
PHE 1 291
 None
 1.17A 2w9sC-1g6q1:
undetectable		 2w9sC-1g6q1:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YK1_H_NCTH300_1
(FAB FRAGMENT, HEAVY
CHAIN
FAB FRAGMENT, LIGHT
CHAIN)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY 1 114
VAL 1 119
TYR 1 149
TYR 1 154
ALA 1 150
 None
 1.40A 2yk1H-1g6q1:
2.4
2yk1L-1g6q1:
0.7		 2yk1H-1g6q1:
20.18
2yk1L-1g6q1:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY 1 172
PHE 1 291
GLU 1 174
LEU 1 243
ILE 1 303
 None
 1.27A 3kvrB-1g6q1:
undetectable		 3kvrB-1g6q1:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 ASP 1 220
LEU 1 307
LEU 1 170
SER 1 167
 None
 0.91A 3lm8A-1g6q1:
undetectable
3lm8C-1g6q1:
undetectable		 3lm8A-1g6q1:
20.48
3lm8C-1g6q1:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 ASP 1 145
SER 1 142
ARG 1 317
 None
 1.00A 3loqA-1g6q1:
4.2		 3loqA-1g6q1:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 GLY 1  70
ILE 1  85
VAL 1  84
 None
 0.49A 3nv6A-1g6q1:
undetectable		 3nv6A-1g6q1:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 TYR 1 178
ILE 1 206
LEU 1 173
GLY 1 253
 None
 0.80A 4iqqA-1g6q1:
0.0		 4iqqA-1g6q1:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 TYR 1 178
ILE 1 206
LEU 1 173
GLY 1 253
 None
 0.72A 4iqqD-1g6q1:
undetectable		 4iqqD-1g6q1:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 GLU 1 132
ARG 1  42
HIS 1 283
 None
 0.81A 4kf9A-1g6q1:
0.0		 4kf9A-1g6q1:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		6 / 10 LEU 1 148
ASP 1 145
LEU 1 116
LEU 1  63
ILE 1 129
LEU 1 227
 None
 1.36A 4odoB-1g6q1:
undetectable		 4odoB-1g6q1:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 11 GLY 1  68
CYH 1  67
SER 1  73
ALA 1  76
MET 1 143
 None
 1.07A 4xumB-1g6q1:
0.0		 4xumB-1g6q1:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 THR 1 110
HIS 1 153
LEU 1 116
 None
 0.73A 5axdA-1g6q1:
5.5		 5axdA-1g6q1:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 THR 1 110
HIS 1 153
LEU 1 116
 None
 0.76A 5axdC-1g6q1:
5.4		 5axdC-1g6q1:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR 1 345
GLY 1 253
TYR 1 325
GLY 1 305
 None
 0.91A 5ayfA-1g6q1:
undetectable		 5ayfA-1g6q1:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 PHE 1 258
ILE 1 260
ASP 1 226
 None
 0.51A 5cswA-1g6q1:
undetectable		 5cswA-1g6q1:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 PHE 1 258
ILE 1 260
ASP 1 226
 None
 0.44A 5cswB-1g6q1:
undetectable		 5cswB-1g6q1:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1g6q HNRNP ARGININE
N-METHYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 TYR 1 178
ILE 1 206
LEU 1 173
GLY 1 253
 None
 0.74A 5nooD-1g6q1:
undetectable		 5nooD-1g6q1:
21.10