SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 9 GLY K 917
GLY K 835
GLU K 806
ARG K 916
GLY K 896
None
1.18A 1jhoA-1g6vK:
undetectable
1jhoA-1g6vK:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
4 / 8 GLY K 917
GLY K 835
ARG K 916
GLY K 896
None
0.72A 1jhqA-1g6vK:
undetectable
1jhqA-1g6vK:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 9 GLY K 917
GLY K 835
GLU K 806
ARG K 916
GLY K 896
None
1.17A 1jhrA-1g6vK:
undetectable
1jhrA-1g6vK:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 9 GLY K 917
GLY K 835
GLU K 806
ARG K 916
GLY K 896
None
1.14A 1jhyA-1g6vK:
undetectable
1jhyA-1g6vK:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 9 GLY K 917
GLY K 835
GLU K 806
ARG K 916
GLY K 896
None
1.21A 1l4nA-1g6vK:
undetectable
1l4nA-1g6vK:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 9 GLY K 917
GLY K 835
GLU K 806
ARG K 916
GLY K 896
None
1.19A 1l5kA-1g6vK:
undetectable
1l5kA-1g6vK:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 9 GLY K 917
GLY K 835
GLU K 806
ARG K 916
GLY K 896
None
1.21A 1l5lA-1g6vK:
undetectable
1l5lA-1g6vK:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 9 GLY K 917
GLY K 835
GLU K 806
ARG K 916
GLY K 896
None
1.21A 1l5mA-1g6vK:
undetectable
1l5mA-1g6vK:
15.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 12 VAL K 802
ALA K 824
MET K 834
ASN K 875
VAL K 877
None
0.84A 3qxtA-1g6vK:
20.4
3qxtA-1g6vK:
70.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
6 / 12 VAL K 802
LEU K 804
ALA K 824
MET K 834
VAL K 877
TYR K 915
None
0.69A 3qxtB-1g6vK:
20.8
3qxtB-1g6vK:
70.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 12 VAL K 802
ALA K 824
MET K 834
VAL K 877
TYR K 915
None
0.83A 3qxvB-1g6vK:
20.3
3qxvB-1g6vK:
69.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 12 VAL K 802
ALA K 824
MET K 834
VAL K 877
TYR K 915
None
0.69A 3qxvD-1g6vK:
20.1
3qxvD-1g6vK:
69.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1g6v ANTIBODY HEAVY CHAIN
(Camelus
dromedarius)
5 / 9 GLY K 917
GLY K 835
GLU K 806
ARG K 916
GLY K 896
None
1.21A 4kqiA-1g6vK:
undetectable
4kqiA-1g6vK:
15.16