SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1g73 SECOND
MITOCHONDRIA-DERIVED
ACTIVATOR OF
CASPASES
(Homo
sapiens) 		3 / 3 THR A  30
LEU A  34
LEU A  41
 None
 0.53A 1mz9C-1g73A:
2.2		 1mz9C-1g73A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1g73 SECOND
MITOCHONDRIA-DERIVED
ACTIVATOR OF
CASPASES
(Homo
sapiens) 		4 / 6 ALA A  44
GLU A  43
ILE A  42
LEU A  98
 None
 1.04A 1xvaA-1g73A:
undetectable
1xvaB-1g73A:
undetectable		 1xvaA-1g73A:
20.28
1xvaB-1g73A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 1g73 SECOND
MITOCHONDRIA-DERIVED
ACTIVATOR OF
CASPASES
(Homo
sapiens) 		5 / 11 SER A  29
VAL A  23
THR A  30
ALA A 115
THR A 119
 None
 1.22A 4e0fA-1g73A:
undetectable		 4e0fA-1g73A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 1g73 SECOND
MITOCHONDRIA-DERIVED
ACTIVATOR OF
CASPASES
(Homo
sapiens) 		3 / 3 TRP A 102
GLU A  99
GLU A 140
 None
 1.01A 6fhwA-1g73A:
2.1		 6fhwA-1g73A:
18.40