SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1g7o GLUTAREDOXIN 2
(Escherichia
coli) 		4 / 6 LEU A  13
ASN A 181
LEU A 210
PHE A 110
 None
 1.27A 1ru9H-1g7oA:
undetectable
1ru9L-1g7oA:
undetectable		 1ru9H-1g7oA:
20.49
1ru9L-1g7oA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1g7o GLUTAREDOXIN 2
(Escherichia
coli) 		4 / 6 LEU A 210
ASN A 181
LEU A  13
PHE A 176
 None
 1.28A 1rukH-1g7oA:
undetectable
1rukL-1g7oA:
undetectable		 1rukH-1g7oA:
20.49
1rukL-1g7oA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 1g7o GLUTAREDOXIN 2
(Escherichia
coli) 		4 / 5 LEU A  28
VAL A 185
LEU A 182
MET A  17
 None
 0.98A 2oiqA-1g7oA:
undetectable		 2oiqA-1g7oA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1g7o GLUTAREDOXIN 2
(Escherichia
coli) 		4 / 4 LEU A  51
ALA A  15
ILE A  18
LYS A  53
 None
 1.48A 4eixA-1g7oA:
0.0		 4eixA-1g7oA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 1g7o GLUTAREDOXIN 2
(Escherichia
coli) 		4 / 6 LEU A  90
ASN A  94
LEU A 179
VAL A 185
 None
 1.11A 4okbA-1g7oA:
undetectable		 4okbA-1g7oA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1g7o GLUTAREDOXIN 2
(Escherichia
coli) 		5 / 12 GLU A  87
ASP A 172
ALA A 153
VAL A 194
TYR A 197
 None
 1.31A 5kbwB-1g7oA:
undetectable		 5kbwB-1g7oA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1g7o GLUTAREDOXIN 2
(Escherichia
coli) 		5 / 12 ILE A   5
VAL A  48
ILE A 207
VAL A  30
PHE A 110
 None
 1.45A 6j21A-1g7oA:
undetectable		 6j21A-1g7oA:
16.90