SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g7r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_A_ADNA601_1 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.27A	1d4fA-1g7rA: 3.2	1d4fA-1g7rA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_B_ADNB602_1 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.24A	1d4fB-1g7rA: 2.0	1d4fB-1g7rA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_C_ADNC603_1 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.27A	1d4fC-1g7rA: 3.3	1d4fC-1g7rA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_D_ADND604_1 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.23A	1d4fD-1g7rA: 2.9	1d4fD-1g7rA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.22A	1v8bA-1g7rA: undetectable	1v8bA-1g7rA: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_B_ADNB1502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.22A	1v8bB-1g7rA: 2.0	1v8bB-1g7rA: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_C_ADNC2502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.22A	1v8bC-1g7rA: 2.2	1v8bC-1g7rA: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_D_ADND3502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.21A	1v8bD-1g7rA: undetectable	1v8bD-1g7rA: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y4L_B_SVRB301_2 (PHOSPHOLIPASE A2 HOMOLOG 2)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 11	LEU A 72 LEU A 212 VAL A 51 GLY A 54 LYS A 61	None	1.47A	1y4lB-1g7rA: undetectable	1y4lB-1g7rA: 12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_E_MK1E902_4 (POL POLYPROTEIN)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	3 / 3	ARG A 119 VAL A 127 GLY A 106	None	0.65A	2avvE-1g7rA: 0.0	2avvE-1g7rA: 10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F7A_B_BEZB1002_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 9	LEU A 209 LEU A 212 ILE A 98 LEU A 22 ILE A 25	None	1.21A	2f7aB-1g7rA: undetectable	2f7aB-1g7rA: 18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KCE_A_D16A566_2 (THYMIDYLATE SYNTHASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	3 / 3	HIS A 41 ILE A 75 LEU A 22	None	0.63A	2kceA-1g7rA: 0.0	2kceA-1g7rA: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_A_2FAA500_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.15A	2zj0A-1g7rA: 3.9	2zj0A-1g7rA: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A25_A_SAMA279_1 (UNCHARACTERIZED PROTEIN PH0793)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	3 / 3	MET A 457 GLU A 570 ASP A 568	None	1.00A	3a25A-1g7rA: undetectable	3a25A-1g7rA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_A_ADNA500_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.17A	3ce6A-1g7rA: undetectable	3ce6A-1g7rA: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_C_ADNC500_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.17A	3ce6C-1g7rA: 3.3	3ce6C-1g7rA: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_C_ADNC438_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.21A	3g1uC-1g7rA: 3.5	3g1uC-1g7rA: 22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_D_ADND438_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.16A	3g1uD-1g7rA: undetectable	3g1uD-1g7rA: 22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_A_RABA602_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.26A	3glqA-1g7rA: 2.8	3glqA-1g7rA: 24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_B_RABB602_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.21A	3glqB-1g7rA: undetectable	3glqB-1g7rA: 24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HY7_B_097B801_1 (A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 9	ASP A 300 LEU A 280 HIS A 41 ILE A 257 LEU A 258	None	1.29A	3hy7B-1g7rA: 3.2	3hy7B-1g7rA: 16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_C_MTXC164_2 (DIHYDROFOLATE REDUCTASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	4 / 4	ILE A 197 ARG A 184 ILE A 195 THR A 201	None	1.11A	3ia4C-1g7rA: 0.6	3ia4C-1g7rA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_A_CGEA501_1 (CYTOCHROME P450 2B4)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 10	VAL A 366 PHE A 429 ILE A 407 VAL A 375 VAL A 353	None	1.05A	3me6A-1g7rA: 0.0	3me6A-1g7rA: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_C_CGEC501_1 (CYTOCHROME P450 2B4)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 9	VAL A 366 PHE A 429 ILE A 407 VAL A 375 VAL A 353	None	1.08A	3me6C-1g7rA: undetectable	3me6C-1g7rA: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_D_CGED501_1 (CYTOCHROME P450 2B4)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 9	VAL A 366 PHE A 429 ILE A 407 VAL A 375 VAL A 353	None	1.10A	3me6D-1g7rA: undetectable	3me6D-1g7rA: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_A_ADNA500_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.23A	3n58A-1g7rA: 3.6	3n58A-1g7rA: 22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_D_ADND500_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.18A	3n58D-1g7rA: 3.6	3n58D-1g7rA: 22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXC_A_ROCA401_3 (PROTEASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 487 GLY A 543 ILE A 531 GLY A 482 ILE A 466	None	0.94A	3oxcB-1g7rA: undetectable	3oxcB-1g7rA: 10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_B_BEZB160_0 (HEME-BINDING PROTEIN HUTZ)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	4 / 4	LEU A 360 GLY A 361 LEU A 363 GLU A 364	None	1.12A	3tgvB-1g7rA: 0.0	3tgvB-1g7rA: 13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_2 (PROTEASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 487 GLY A 543 ILE A 531 GLY A 482 ILE A 466	None	0.91A	3tkgD-1g7rA: undetectable	3tkgD-1g7rA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_A_CHDA1503_0 (FERROCHELATASE, MITOCHONDRIAL)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	4 / 8	ILE A 466 LEU A 468 VAL A 505 GLY A 506	None	0.87A	3w1wA-1g7rA: 4.0	3w1wA-1g7rA: 20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLA_A_CHDA502_0 (FERROCHELATASE, MITOCHONDRIAL)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	4 / 8	LEU A 69 LEU A 224 ILE A 52 VAL A 8	None	0.84A	4klaA-1g7rA: 2.0	4klaA-1g7rA: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LVC_A_ADNA501_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE (SAHASE))	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.23A	4lvcA-1g7rA: 3.4	4lvcA-1g7rA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LVC_B_ADNB501_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE (SAHASE))	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.16A	4lvcB-1g7rA: undetectable	4lvcB-1g7rA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LVC_C_ADNC501_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE (SAHASE))	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.18A	4lvcC-1g7rA: undetectable	4lvcC-1g7rA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NTX_A_AMRA509_1 (ACID-SENSING ION CHANNEL 1 BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	4 / 6	GLU A 174 GLU A 439 ASN A 116 ARG A 119	None	1.34A	4ntxA-1g7rA: 0.0 4ntxC-1g7rA: undetectable	4ntxA-1g7rA: 22.44 4ntxC-1g7rA: 9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.24A	4pfjA-1g7rA: 4.2	4pfjA-1g7rA: 23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGF_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.26A	4pgfA-1g7rA: 3.3	4pgfA-1g7rA: 23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q1X_A_017A101_1 (ASPARTYL PROTEASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 11	GLY A 234 ILE A 75 GLY A 307 ILE A 308 VAL A 239	None	0.94A	4q1xA-1g7rA: undetectable	4q1xA-1g7rA: 10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z69_A_DIFA1006_1 (SERUM ALBUMIN)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	4 / 7	ILE A 75 LEU A 237 GLY A 307 LYS A 40	None	1.02A	4z69A-1g7rA: 0.0	4z69A-1g7rA: 22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXA_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.17A	5axaA-1g7rA: 3.3	5axaA-1g7rA: 23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXA_C_ADNC502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.19A	5axaC-1g7rA: 2.9	5axaC-1g7rA: 23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_B_SAMB301_0 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	GLY A 204 GLY A 202 ALA A 199 ALA A 128 ILE A 195	None	1.04A	5bw4B-1g7rA: undetectable	5bw4B-1g7rA: 20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E5J_A_017A201_1 (PROTEASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	6 / 12	LEU A 280 ALA A 312 ILE A 249 VAL A 318 ILE A 308 ILE A 310	None	1.32A	5e5jA-1g7rA: undetectable	5e5jA-1g7rA: 10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_A_ADNA501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5hm8A-1g7rA: 3.3	5hm8A-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_B_ADNB501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5hm8B-1g7rA: 3.1	5hm8B-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_C_ADNC501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5hm8C-1g7rA: 3.4	5hm8C-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_D_ADND501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5hm8D-1g7rA: 3.7	5hm8D-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_E_ADNE501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5hm8E-1g7rA: undetectable	5hm8E-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_F_ADNF501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.21A	5hm8F-1g7rA: 2.4	5hm8F-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_G_ADNG501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5hm8G-1g7rA: 2.3	5hm8G-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_H_ADNH501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5hm8H-1g7rA: 2.1	5hm8H-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.16A	5m5kA-1g7rA: 2.3	5m5kA-1g7rA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_B_ADNB502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.17A	5m5kB-1g7rA: 2.1	5m5kB-1g7rA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_C_ADNC502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.15A	5m5kC-1g7rA: undetectable	5m5kC-1g7rA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.15A	5m66A-1g7rA: undetectable	5m66A-1g7rA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_B_ADNB502_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.17A	5m66B-1g7rA: 3.4	5m66B-1g7rA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UTU_F_ADNF503_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5utuF-1g7rA: undetectable	5utuF-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UTU_H_ADNH503_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.20A	5utuH-1g7rA: 2.2	5utuH-1g7rA: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_A_ADNA502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.15A	5v96A-1g7rA: 2.0	5v96A-1g7rA: 23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_B_ADNB502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.17A	5v96B-1g7rA: undetectable	5v96B-1g7rA: 23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_C_ADNC502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.16A	5v96C-1g7rA: undetectable	5v96C-1g7rA: 23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_D_ADND502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.14A	5v96D-1g7rA: 3.3	5v96D-1g7rA: 23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_A_C2FA3001_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	3 / 3	ASP A 501 ASN A 499 ASP A 544	None	0.80A	5vopA-1g7rA: 3.4	5vopA-1g7rA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_B_C2FB3001_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	3 / 3	ASP A 501 ASN A 499 ASP A 544	None	0.80A	5vopB-1g7rA: undetectable	5vopB-1g7rA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6APH_A_ADNA501_1 (ADENOSYLHOMOCYSTEINA SE)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.21A	6aphA-1g7rA: 2.7	6aphA-1g7rA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_A_ADNA501_1 (-)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.22A	6gbnA-1g7rA: 3.5	6gbnA-1g7rA: 23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_B_ADNB501_1 (-)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.23A	6gbnB-1g7rA: 3.3	6gbnB-1g7rA: 23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_C_ADNC501_1 (-)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.22A	6gbnC-1g7rA: 3.5	6gbnC-1g7rA: 23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_D_ADND501_1 (-)	1g7r	TRANSLATION INITIATION FACTOR IF2/EIF5B (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 161 ASP A 162 ASP A 183 MET A 147 PHE A 146	None	1.22A	6gbnD-1g7rA: 3.4	6gbnD-1g7rA: 23.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D4F_A_ADNA601_1","S-ADENOSYLHOMOCYSTEINE HYDROLASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.27A","1d4fA-1g7rA:3.2","1d4fA-1g7rA:22.76"],["1D4F_B_ADNB602_1","S-ADENOSYLHOMOCYSTEINE HYDROLASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.24A","1d4fB-1g7rA:2.0","1d4fB-1g7rA:22.76"],["1D4F_C_ADNC603_1","S-ADENOSYLHOMOCYSTEINE HYDROLASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.27A","1d4fC-1g7rA:3.3","1d4fC-1g7rA:22.76"],["1D4F_D_ADND604_1","S-ADENOSYLHOMOCYSTEINE HYDROLASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.23A","1d4fD-1g7rA:2.9","1d4fD-1g7rA:22.76"],["1V8B_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.22A","1v8bA-1g7rA:undetectable","1v8bA-1g7rA:22.68"],["1V8B_B_ADNB1502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.22A","1v8bB-1g7rA:2.0","1v8bB-1g7rA:22.68"],["1V8B_C_ADNC2502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.22A","1v8bC-1g7rA:2.2","1v8bC-1g7rA:22.68"],["1V8B_D_ADND3502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.21A","1v8bD-1g7rA:undetectable","1v8bD-1g7rA:22.68"],["1Y4L_B_SVRB301_2","PHOSPHOLIPASE A2 HOMOLOG 2","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A  72;LEU A 212;VAL A  51;GLY A  54;LYS A  61","None","1.47A","1y4lB-1g7rA:undetectable","1y4lB-1g7rA:12.05"],["2AVV_E_MK1E902_4","POL POLYPROTEIN","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",3,"ARG A 119;VAL A 127;GLY A 106","None","0.65A","2avvE-1g7rA:0.0","2avvE-1g7rA:10.77"],["2F7A_B_BEZB1002_0","HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 209;LEU A 212;ILE A  98;LEU A  22;ILE A  25","None","1.21A","2f7aB-1g7rA:undetectable","2f7aB-1g7rA:18.44"],["2KCE_A_D16A566_2","THYMIDYLATE SYNTHASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",3,"HIS A  41;ILE A  75;LEU A  22","None","0.63A","2kceA-1g7rA:0.0","2kceA-1g7rA:16.72"],["2ZJ0_A_2FAA500_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.15A","2zj0A-1g7rA:3.9","2zj0A-1g7rA:22.99"],["3A25_A_SAMA279_1","UNCHARACTERIZED PROTEIN PH0793","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",3,"MET A 457;GLU A 570;ASP A 568","None","1.00A","3a25A-1g7rA:undetectable","3a25A-1g7rA:23.08"],["3CE6_A_ADNA500_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.17A","3ce6A-1g7rA:undetectable","3ce6A-1g7rA:22.38"],["3CE6_C_ADNC500_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.17A","3ce6C-1g7rA:3.3","3ce6C-1g7rA:22.38"],["3G1U_C_ADNC438_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.21A","3g1uC-1g7rA:3.5","3g1uC-1g7rA:22.24"],["3G1U_D_ADND438_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.16A","3g1uD-1g7rA:undetectable","3g1uD-1g7rA:22.24"],["3GLQ_A_RABA602_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.26A","3glqA-1g7rA:2.8","3glqA-1g7rA:24.49"],["3GLQ_B_RABB602_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.21A","3glqB-1g7rA:undetectable","3glqB-1g7rA:24.49"],["3HY7_B_097B801_1","A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"ASP A 300;LEU A 280;HIS A  41;ILE A 257;LEU A 258","None","1.29A","3hy7B-1g7rA:3.2","3hy7B-1g7rA:16.38"],["3IA4_C_MTXC164_2","DIHYDROFOLATE REDUCTASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",4,"ILE A 197;ARG A 184;ILE A 195;THR A 201","None","1.11A","3ia4C-1g7rA:0.6","3ia4C-1g7rA:14.73"],["3ME6_A_CGEA501_1","CYTOCHROME P450 2B4","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"VAL A 366;PHE A 429;ILE A 407;VAL A 375;VAL A 353","None","1.05A","3me6A-1g7rA:0.0","3me6A-1g7rA:21.46"],["3ME6_C_CGEC501_1","CYTOCHROME P450 2B4","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"VAL A 366;PHE A 429;ILE A 407;VAL A 375;VAL A 353","None","1.08A","3me6C-1g7rA:undetectable","3me6C-1g7rA:21.46"],["3ME6_D_CGED501_1","CYTOCHROME P450 2B4","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"VAL A 366;PHE A 429;ILE A 407;VAL A 375;VAL A 353","None","1.10A","3me6D-1g7rA:undetectable","3me6D-1g7rA:21.46"],["3N58_A_ADNA500_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.23A","3n58A-1g7rA:3.6","3n58A-1g7rA:22.75"],["3N58_D_ADND500_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.18A","3n58D-1g7rA:3.6","3n58D-1g7rA:22.75"],["3OXC_A_ROCA401_3","PROTEASE;PROTEASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 487;GLY A 543;ILE A 531;GLY A 482;ILE A 466","None","0.94A","3oxcB-1g7rA:undetectable","3oxcB-1g7rA:10.94"],["3TGV_B_BEZB160_0","HEME-BINDING PROTEIN HUTZ","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",4,"LEU A 360;GLY A 361;LEU A 363;GLU A 364","None","1.12A","3tgvB-1g7rA:0.0","3tgvB-1g7rA:13.97"],["3TKG_C_ROCC901_2","PROTEASE;PROTEASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 487;GLY A 543;ILE A 531;GLY A 482;ILE A 466","None","0.91A","3tkgD-1g7rA:undetectable","3tkgD-1g7rA:12.26"],["3W1W_A_CHDA1503_0","FERROCHELATASE, MITOCHONDRIAL","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",4,"ILE A 466;LEU A 468;VAL A 505;GLY A 506","None","0.87A","3w1wA-1g7rA:4.0","3w1wA-1g7rA:20.86"],["4KLA_A_CHDA502_0","FERROCHELATASE, MITOCHONDRIAL","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",4,"LEU A  69;LEU A 224;ILE A  52;VAL A   8","None","0.84A","4klaA-1g7rA:2.0","4klaA-1g7rA:20.90"],["4LVC_A_ADNA501_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (SAHASE)","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.23A","4lvcA-1g7rA:3.4","4lvcA-1g7rA:23.21"],["4LVC_B_ADNB501_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (SAHASE)","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.16A","4lvcB-1g7rA:undetectable","4lvcB-1g7rA:23.21"],["4LVC_C_ADNC501_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (SAHASE)","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.18A","4lvcC-1g7rA:undetectable","4lvcC-1g7rA:23.21"],["4NTX_A_AMRA509_1","ACID-SENSING ION CHANNEL 1;BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",4,"GLU A 174;GLU A 439;ASN A 116;ARG A 119","None","1.34A","4ntxA-1g7rA:0.0;4ntxC-1g7rA:undetectable","4ntxA-1g7rA:22.44;4ntxC-1g7rA:9.90"],["4PFJ_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.24A","4pfjA-1g7rA:4.2","4pfjA-1g7rA:23.10"],["4PGF_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.26A","4pgfA-1g7rA:3.3","4pgfA-1g7rA:23.10"],["4Q1X_A_017A101_1","ASPARTYL PROTEASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"GLY A 234;ILE A  75;GLY A 307;ILE A 308;VAL A 239","None","0.94A","4q1xA-1g7rA:undetectable","4q1xA-1g7rA:10.44"],["4Z69_A_DIFA1006_1","SERUM ALBUMIN","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",4,"ILE A  75;LEU A 237;GLY A 307;LYS A  40","None","1.02A","4z69A-1g7rA:0.0","4z69A-1g7rA:22.21"],["5AXA_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.17A","5axaA-1g7rA:3.3","5axaA-1g7rA:23.27"],["5AXA_C_ADNC502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.19A","5axaC-1g7rA:2.9","5axaC-1g7rA:23.27"],["5BW4_B_SAMB301_0","16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"GLY A 204;GLY A 202;ALA A 199;ALA A 128;ILE A 195","None","1.04A","5bw4B-1g7rA:undetectable","5bw4B-1g7rA:20.13"],["5E5J_A_017A201_1","PROTEASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",6,"LEU A 280;ALA A 312;ILE A 249;VAL A 318;ILE A 308;ILE A 310","None","1.32A","5e5jA-1g7rA:undetectable","5e5jA-1g7rA:10.44"],["5HM8_A_ADNA501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5hm8A-1g7rA:3.3","5hm8A-1g7rA:22.87"],["5HM8_B_ADNB501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5hm8B-1g7rA:3.1","5hm8B-1g7rA:22.87"],["5HM8_C_ADNC501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5hm8C-1g7rA:3.4","5hm8C-1g7rA:22.87"],["5HM8_D_ADND501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5hm8D-1g7rA:3.7","5hm8D-1g7rA:22.87"],["5HM8_E_ADNE501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5hm8E-1g7rA:undetectable","5hm8E-1g7rA:22.87"],["5HM8_F_ADNF501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.21A","5hm8F-1g7rA:2.4","5hm8F-1g7rA:22.87"],["5HM8_G_ADNG501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5hm8G-1g7rA:2.3","5hm8G-1g7rA:22.87"],["5HM8_H_ADNH501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5hm8H-1g7rA:2.1","5hm8H-1g7rA:22.87"],["5M5K_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.16A","5m5kA-1g7rA:2.3","5m5kA-1g7rA:23.21"],["5M5K_B_ADNB502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.17A","5m5kB-1g7rA:2.1","5m5kB-1g7rA:23.21"],["5M5K_C_ADNC502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.15A","5m5kC-1g7rA:undetectable","5m5kC-1g7rA:23.21"],["5M66_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.15A","5m66A-1g7rA:undetectable","5m66A-1g7rA:23.21"],["5M66_B_ADNB502_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.17A","5m66B-1g7rA:3.4","5m66B-1g7rA:23.21"],["5UTU_F_ADNF503_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5utuF-1g7rA:undetectable","5utuF-1g7rA:22.87"],["5UTU_H_ADNH503_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.20A","5utuH-1g7rA:2.2","5utuH-1g7rA:22.87"],["5V96_A_ADNA502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.15A","5v96A-1g7rA:2.0","5v96A-1g7rA:23.39"],["5V96_B_ADNB502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.17A","5v96B-1g7rA:undetectable","5v96B-1g7rA:23.39"],["5V96_C_ADNC502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.16A","5v96C-1g7rA:undetectable","5v96C-1g7rA:23.39"],["5V96_D_ADND502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.14A","5v96D-1g7rA:3.3","5v96D-1g7rA:23.39"],["5VOP_A_C2FA3001_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",3,"ASP A 501;ASN A 499;ASP A 544","None","0.80A","5vopA-1g7rA:3.4","5vopA-1g7rA:22.35"],["5VOP_B_C2FB3001_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",3,"ASP A 501;ASN A 499;ASP A 544","None","0.80A","5vopB-1g7rA:undetectable","5vopB-1g7rA:22.35"],["6APH_A_ADNA501_1","ADENOSYLHOMOCYSTEINASE","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.21A","6aphA-1g7rA:2.7","6aphA-1g7rA:20.83"],["6GBN_A_ADNA501_1","-","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.22A","6gbnA-1g7rA:3.5","6gbnA-1g7rA:23.10"],["6GBN_B_ADNB501_1","-","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.23A","6gbnB-1g7rA:3.3","6gbnB-1g7rA:23.10"],["6GBN_C_ADNC501_1","-","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.22A","6gbnC-1g7rA:3.5","6gbnC-1g7rA:23.10"],["6GBN_D_ADND501_1","-","1g7r","TRANSLATION INITIATION FACTOR IF2\/EIF5B","Methanothermobacter thermautotrophicus",5,"LEU A 161;ASP A 162;ASP A 183;MET A 147;PHE A 146","None","1.22A","6gbnD-1g7rA:3.4","6gbnD-1g7rA:23.10"]]