SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		5 / 12 ILE A 164
GLY A 235
VAL A  13
ALA A 225
LEU A 255
 None
 1.03A 1kiaC-1g7uA:
undetectable		 1kiaC-1g7uA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		5 / 12 ILE A 164
GLY A 235
VAL A  13
ALA A 225
LEU A 255
 None
 1.02A 1nbhB-1g7uA:
undetectable		 1nbhB-1g7uA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		6 / 12 HIS A  40
ILE A  37
GLY A  24
LEU A 236
VAL A  20
ILE A  50
 None
 1.10A 1zq9A-1g7uA:
undetectable		 1zq9A-1g7uA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		5 / 12 SER A  57
MET A 148
PHE A 155
ILE A 151
GLU A 239
 None
 1.42A 3aocC-1g7uA:
0.0		 3aocC-1g7uA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		4 / 6 SER A  57
GLN A 113
PHE A 237
HIS A 202
 None
None
None
PEP  A 300 (-3.9A)
 1.46A 3lskB-1g7uA:
0.4		 3lskB-1g7uA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		4 / 6 SER A  57
GLN A 113
PHE A 237
HIS A 202
 None
None
None
PEP  A 300 (-3.9A)
 1.45A 3lskD-1g7uA:
0.0		 3lskD-1g7uA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		5 / 9 GLN A 113
ILE A 112
THR A 201
PHE A 237
GLU A 239
 None
 1.33A 3qelD-1g7uA:
undetectable		 3qelD-1g7uA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		4 / 6 ALA A  34
ILE A  80
GLU A 245
GLU A  29
 None
 0.81A 3r9sA-1g7uA:
undetectable		 3r9sA-1g7uA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		4 / 5 ASP A 199
ASP A  59
ASN A  26
GLU A 239
 None
 1.18A 3vywD-1g7uA:
1.6		 3vywD-1g7uA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		5 / 9 GLY A  23
LEU A  21
GLN A 205
LEU A 255
LEU A 260
 None
None
PEP  A 300 ( 3.8A)
None
None
 1.45A 5fhzB-1g7uA:
undetectable		 5fhzB-1g7uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		4 / 7 ILE A 238
THR A  45
ILE A  50
PHE A 263
 None
 0.64A 5fukA-1g7uA:
0.1
5fukB-1g7uA:
0.0		 5fukA-1g7uA:
23.41
5fukB-1g7uA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		4 / 4 HIS A 241
HIS A 246
TYR A  69
GLU A  29
 None
 1.44A 5pahA-1g7uA:
undetectable		 5pahA-1g7uA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		3 / 3 MET A 267
GLU A 223
ARG A 226
 None
 1.13A 5tjyA-1g7uA:
undetectable		 5tjyA-1g7uA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		5 / 12 LEU A 114
PRO A 115
PHE A 155
THR A 131
ILE A 135
 None
 1.12A 6debB-1g7uA:
undetectable		 6debB-1g7uA:
14.23