SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g7y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		5 / 10 ALA A  73
LEU A 179
LEU A 156
ALA A 157
ILE A  75
 None
 1.25A 1g5yC-1g7yA:
undetectable		 1g5yC-1g7yA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		5 / 11 SER A 148
LEU A 105
GLY A 140
HIS A 222
GLU A 220
 MN  A 257 ( 4.3A)
None
None
None
None
 1.44A 1iolA-1g7yA:
undetectable		 1iolA-1g7yA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		4 / 6 LEU A 165
ALA A  68
SER A 228
SER A   7
 None
 0.55A 1tz8C-1g7yA:
0.5
1tz8D-1g7yA:
0.1		 1tz8C-1g7yA:
21.79
1tz8D-1g7yA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		5 / 10 LEU A 179
ILE A 164
VAL A 122
ALA A 121
LEU A 105
 None
 1.19A 1xp0A-1g7yA:
undetectable		 1xp0A-1g7yA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		5 / 12 VAL A 204
LEU A  91
ILE A   3
ASP A   2
LEU A 242
 None
 1.14A 3cjtK-1g7yA:
undetectable		 3cjtK-1g7yA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		4 / 4 SER A 226
SER A  70
THR A  69
SER A 228
 None
 1.15A 3loqA-1g7yA:
undetectable		 3loqA-1g7yA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		3 / 3 PHE A 208
TYR A  50
LEU A  45
 None
 0.79A 3sueB-1g7yA:
0.0		 3sueB-1g7yA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		5 / 12 ALA A 245
ASP A 243
LEU A 242
LYS A 240
SER A 228
 None
 1.11A 4ky8C-1g7yA:
undetectable		 4ky8C-1g7yA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		3 / 3 VAL A  34
THR A 221
ARG A  30
 None
 0.78A 5b2sB-1g7yA:
undetectable		 5b2sB-1g7yA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		4 / 8 ASP A 125
HIS A 181
ARG A 137
HIS A 138
 CA  A 254 ( 2.2A)
None
None
MN  A 257 (-3.4A)
 1.10A 6mn4A-1g7yA:
0.0		 6mn4A-1g7yA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1g7y STEM/LEAF LECTIN
DB58
(Vigna
unguiculata) 		4 / 8 ASP A 125
HIS A 181
ARG A 137
HIS A 138
 CA  A 254 ( 2.2A)
None
None
MN  A 257 (-3.4A)
 1.06A 6mn4B-1g7yA:
0.0		 6mn4B-1g7yA:
22.64