SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		3 / 3 GLU A 199
ILE A  60
ARG A  64
 None
 0.85A 1cd2A-1g82A:
undetectable		 1cd2A-1g82A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		3 / 3 ASP A 203
LYS A  58
ARG A  62
 None
 1.12A 1ra8A-1g82A:
undetectable		 1ra8A-1g82A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		4 / 4 GLU A 120
GLY A 122
THR A 176
GLU A 174
 None
 1.20A 3e9xA-1g82A:
undetectable		 3e9xA-1g82A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		3 / 3 GLU A 123
GLY A 175
THR A 176
 None
 0.58A 3iazA-1g82A:
undetectable		 3iazA-1g82A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		4 / 5 GLU A 123
GLY A 122
TYR A 125
GLU A 133
 None
 1.44A 3w9tA-1g82A:
13.3		 3w9tA-1g82A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		4 / 5 GLU A 123
GLY A 122
TYR A 125
GLU A 133
 None
 1.44A 3w9tC-1g82A:
13.4		 3w9tC-1g82A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		4 / 5 GLU A 123
GLY A 122
TYR A 125
GLU A 133
 None
 1.44A 3w9tD-1g82A:
12.4		 3w9tD-1g82A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		4 / 5 GLU A 123
GLY A 122
TYR A 125
GLU A 133
 None
 1.44A 3w9tG-1g82A:
13.3		 3w9tG-1g82A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens) 		5 / 12 ILE A  82
LEU A  74
SER A 112
GLY A 126
GLY A 109
 None
 0.95A 5nnaB-1g82A:
undetectable		 5nnaB-1g82A:
20.00