SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICT_D_T44D129_2 (TRANSTHYRETIN)	1g84	IMMUNOGLOBULIN E (Homo sapiens)	4 / 7	LYS A 10 LEU A 12 THR A 8 LEU A 29	None	0.76A	1ictD-1g84A: undetectable	1ictD-1g84A: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_ACTA1181_0 (WNT INHIBITORY FACTOR 1)	1g84	IMMUNOGLOBULIN E (Homo sapiens)	3 / 3	TYR A 92 VAL A 32 THR A 96	None	0.74A	2ygnA-1g84A: 1.9	2ygnA-1g84A: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IFX_A_ACTA404_0 (THIAMINE BIOSYNTHESIS LIPOPROTEIN APBE)	1g84	IMMUNOGLOBULIN E (Homo sapiens)	4 / 5	LYS A 78 ARG A 84 LEU A 75 ASP A 52	None	1.31A	4ifxA-1g84A: 0.1	4ifxA-1g84A: 14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IG1_A_ACTA504_0 (FAD:PROTEIN FMN TRANSFERASE)	1g84	IMMUNOGLOBULIN E (Homo sapiens)	4 / 5	LYS A 78 ARG A 84 LEU A 75 ASP A 52	None	1.35A	4ig1A-1g84A: 0.0	4ig1A-1g84A: 14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IKL_A_SUZA201_1 (TRANSTHYRETIN)	1g84	IMMUNOGLOBULIN E (Homo sapiens)	4 / 7	LYS A 10 LEU A 12 LEU A 29 SER A 59	None	0.93A	4iklA-1g84A: 1.0 4iklB-1g84A: 0.9	4iklA-1g84A: 22.22 4iklB-1g84A: 22.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICT_D_T44D129_2","TRANSTHYRETIN","1g84","IMMUNOGLOBULIN E","Homo sapiens",4,"LYS A  10;LEU A  12;THR A   8;LEU A  29","None","0.76A","1ictD-1g84A:undetectable","1ictD-1g84A:22.22"],["2YGN_A_ACTA1181_0","WNT INHIBITORY FACTOR 1","1g84","IMMUNOGLOBULIN E","Homo sapiens",3,"TYR A  92;VAL A  32;THR A  96","None","0.74A","2ygnA-1g84A:1.9","2ygnA-1g84A:20.26"],["4IFX_A_ACTA404_0","THIAMINE BIOSYNTHESIS LIPOPROTEIN APBE","1g84","IMMUNOGLOBULIN E","Homo sapiens",4,"LYS A  78;ARG A  84;LEU A  75;ASP A  52","None","1.31A","4ifxA-1g84A:0.1","4ifxA-1g84A:14.33"],["4IG1_A_ACTA504_0","FAD:PROTEIN FMN TRANSFERASE","1g84","IMMUNOGLOBULIN E","Homo sapiens",4,"LYS A  78;ARG A  84;LEU A  75;ASP A  52","None","1.35A","4ig1A-1g84A:0.0","4ig1A-1g84A:14.33"],["4IKL_A_SUZA201_1","TRANSTHYRETIN;TRANSTHYRETIN","1g84","IMMUNOGLOBULIN E","Homo sapiens",4,"LYS A  10;LEU A  12;LEU A  29;SER A  59","None","0.93A","4iklA-1g84A:1.0;4iklB-1g84A:0.9","4iklA-1g84A:22.22;4iklB-1g84A:22.22"]]