SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g8k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 THR A 770
VAL A 746
THR A 755
VAL A 784
 None
 1.08A 1dz9A-1g8kA:
0.0		 1dz9A-1g8kA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 8 ASP A 669
PHE A 666
THR A 668
ASP A 670
HIS A 674
 None
 1.44A 1ei6C-1g8kA:
2.5		 1ei6C-1g8kA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 179
ALA A 567
LEU A 565
TRP A 595
LEU A 574
 None
 1.06A 1errA-1g8kA:
undetectable		 1errA-1g8kA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 10 ALA A 222
ARG A 295
ALA A 271
PHE A 243
ILE A 228
 None
 1.19A 1g5yC-1g8kA:
undetectable		 1g5yC-1g8kA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ASN A 464
ILE A 194
ASN A 201
THR A 789
 None
 1.06A 1h7xA-1g8kA:
undetectable		 1h7xA-1g8kA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ASN A 464
ILE A 194
ASN A 201
THR A 789
 None
 1.05A 1h7xB-1g8kA:
undetectable		 1h7xB-1g8kA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ASN A 464
ILE A 194
ASN A 201
THR A 789
 None
 1.06A 1h7xC-1g8kA:
undetectable		 1h7xC-1g8kA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ASN A 464
ILE A 194
ASN A 201
THR A 789
 None
 1.06A 1h7xD-1g8kA:
undetectable		 1h7xD-1g8kA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 THR A 770
VAL A 746
THR A 755
VAL A 784
 None
 1.07A 1o76B-1g8kA:
0.0		 1o76B-1g8kA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ARG A 815
ASP A 115
ASN A 716
GLU A 812
 None
 1.15A 1rjdA-1g8kA:
3.5		 1rjdA-1g8kA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ARG A 815
ASP A 115
ASN A 716
GLU A 812
 None
 1.15A 1rjdB-1g8kA:
3.3		 1rjdB-1g8kA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ARG A 815
ASP A 115
ASN A 716
GLU A 812
 None
 1.17A 1rjdC-1g8kA:
3.4		 1rjdC-1g8kA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 PHE A 460
ASN A 458
SER A 162
ARG A 193
 None
 1.37A 1rqpB-1g8kA:
undetectable		 1rqpB-1g8kA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 LYS B  74
ILE B  94
THR B  67
 None
 0.82A 1rx3A-1g8kB:
undetectable		 1rx3A-1g8kB:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 LEU A 574
TYR A 143
LEU A 151
TYR A 578
 None
 0.78A 1s1xA-1g8kA:
undetectable		 1s1xA-1g8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 PHE A 161
ILE A 499
THR A 511
THR A 453
 None
 0.96A 1sbrB-1g8kA:
0.0		 1sbrB-1g8kA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 PRO A 303
ASP A 306
ASP A 277
 None
MGD  A5002 (-3.0A)
MGD  A5002 (-2.8A)
 0.73A 1sqfA-1g8kA:
2.2		 1sqfA-1g8kA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 LEU A 244
ASN A 245
LEU A 248
GLN A 252
LEU A  61
 None
 1.07A 1sqnB-1g8kA:
undetectable		 1sqnB-1g8kA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 GLY A 534
ILE A  83
HIS A 532
HIS A  22
VAL A  32
 None
 1.22A 1tmxB-1g8kA:
undetectable		 1tmxB-1g8kA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 GLY A 534
ILE A  83
HIS A 532
HIS A  22
VAL A  85
 None
 1.10A 1tmxB-1g8kA:
undetectable		 1tmxB-1g8kA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1g8k ARSENITE OXIDASE
ARSENITE OXIDASE
(Alcaligenes
faecalis;
Alcaligenes
faecalis) 		4 / 7 TYR A 727
THR B  75
GLU B  88
VAL A 762
 None
 0.94A 1tv8B-1g8kA:
0.0		 1tv8B-1g8kA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 10 TYR A 368
TYR A 383
ALA A 406
LEU A 401
PHE A 310
 None
HG  A6005 (-4.6A)
None
None
None
 1.47A 1uhoA-1g8kA:
undetectable		 1uhoA-1g8kA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ALA A 466
SER A 463
ILE A 445
ASP A 441
 None
 0.90A 1yc2A-1g8kA:
3.1		 1yc2A-1g8kA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 ALA A 466
SER A 463
ILE A 445
ASP A 441
 None
 0.88A 1yc5A-1g8kA:
3.1		 1yc5A-1g8kA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 5 TRP A 801
GLY A 304
ASN A 391
GLY A 682
 None
MGD  A5002 (-3.6A)
None
None
 1.11A 1zlqA-1g8kA:
0.0		 1zlqA-1g8kA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 9 GLN A 690
PHE A 752
GLY A 753
GLU A 747
ALA A 468
 None
 1.26A 2drdA-1g8kA:
0.0		 2drdA-1g8kA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 LEU A  58
ARG A   6
THR A   8
LEU A   9
 None
 1.01A 2dysN-1g8kA:
undetectable
2dysW-1g8kA:
undetectable		 2dysN-1g8kA:
20.91
2dysW-1g8kA:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 179
ALA A 567
LEU A 565
TRP A 595
LEU A 574
 None
 1.08A 2jfaA-1g8kA:
undetectable		 2jfaA-1g8kA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 ASP A 497
TYR A 500
LYS A 153
 None
 1.13A 2othA-1g8kA:
undetectable		 2othA-1g8kA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 6 ILE A 301
PHE A 310
TRP A 229
GLY A 232
GLY A 386
 None
None
None
MGD  A5002 (-3.2A)
MGD  A5002 (-3.1A)
 1.25A 2qx6A-1g8kA:
undetectable
2qx6B-1g8kA:
2.5		 2qx6A-1g8kA:
14.95
2qx6B-1g8kA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 179
ALA A 567
LEU A 565
TRP A 595
LEU A 574
 None
 1.01A 2qxsA-1g8kA:
undetectable		 2qxsA-1g8kA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 179
ALA A 567
LEU A 565
TRP A 595
LEU A 574
 None
 0.94A 2qxsB-1g8kA:
undetectable		 2qxsB-1g8kA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 MET A 183
THR A 189
GLY A 158
THR A 150
LEU A 574
 None
 1.17A 2uvnA-1g8kA:
0.0		 2uvnA-1g8kA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 PHE A 460
ASN A 458
SER A 162
ARG A 193
 None
 1.43A 2v7uB-1g8kA:
undetectable		 2v7uB-1g8kA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 HIS A  22
MET A  19
MET A 105
 None
 0.98A 2vj1A-1g8kA:
0.0		 2vj1A-1g8kA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 HIS A  22
MET A  19
MET A 109
 None
 1.21A 2vj1A-1g8kA:
0.0		 2vj1A-1g8kA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 ASN A 393
THR A 207
GLN A 397
LEU A 400
ILE A 387
 None
HG  A6005 ( 4.7A)
HG  A6005 (-2.2A)
None
None
 1.06A 2xrlA-1g8kA:
0.0		 2xrlA-1g8kA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 GLY A 171
GLY A 426
GLY A 172
 None
 0.41A 3bogD-1g8kA:
undetectable		 3bogD-1g8kA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 TYR A 242
GLN A 620
MET A 541
GLU A 214
 None
 1.43A 3dh0A-1g8kA:
3.1		 3dh0A-1g8kA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 1g8k ARSENITE OXIDASE
ARSENITE OXIDASE
(Alcaligenes
faecalis;
Alcaligenes
faecalis) 		5 / 12 MET A  69
THR A  70
ALA B 100
VAL A  63
VAL B 121
 None
 1.23A 3dl9A-1g8kA:
0.0		 3dl9A-1g8kA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 TYR A 797
ASP A 441
HIS A 195
 MGD  A5001 (-3.8A)
None
MGD  A5001 (-4.5A)
 0.91A 3e23A-1g8kA:
undetectable		 3e23A-1g8kA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 GLY A 213
GLY A 211
MET A 210
ASN A 216
VAL A 410
 None
 1.39A 3f8wB-1g8kA:
undetectable		 3f8wB-1g8kA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 10 ALA A 363
LEU A 299
LEU A 309
ILE A 231
LEU A 400
 None
 1.10A 3fl9E-1g8kA:
undetectable		 3fl9E-1g8kA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1g8k ARSENITE OXIDASE
ARSENITE OXIDASE
(Alcaligenes
faecalis;
Alcaligenes
faecalis) 		3 / 3 ASP A   5
LEU B 124
GLN A  57
 None
 0.70A 3g4lA-1g8kA:
undetectable		 3g4lA-1g8kA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 TYR A 143
PHE A 161
ALA A 186
PHE A 590
LEU A 151
 None
 1.29A 3gwuA-1g8kA:
undetectable		 3gwuA-1g8kA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 10 LEU A 633
THR A 539
LEU A 643
GLY A 621
PHE A 602
 None
 1.23A 3h9uA-1g8kA:
undetectable		 3h9uA-1g8kA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 10 LEU A 633
THR A 539
LEU A 643
GLY A 621
PHE A 602
 None
 1.25A 3h9uC-1g8kA:
undetectable		 3h9uC-1g8kA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 10 LEU A 633
THR A 539
LEU A 643
GLY A 621
PHE A 602
 None
 1.24A 3h9uD-1g8kA:
undetectable		 3h9uD-1g8kA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 GLY A 172
GLY A 426
ALA A 169
LEU A 538
SER A 619
 None
None
MGD  A5001 ( 4.6A)
None
None
 1.06A 3p2kD-1g8kA:
2.3		 3p2kD-1g8kA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 GLY A 390
GLY A 304
THR A 305
LEU A 309
GLY A 386
 MGD  A5002 ( 4.9A)
MGD  A5002 (-3.6A)
None
None
MGD  A5002 (-3.1A)
 1.03A 3sglA-1g8kA:
2.2		 3sglA-1g8kA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 GLY A 605
LEU A 182
GLY A 178
PHE A 593
ALA A 186
 None
 1.02A 3sufA-1g8kA:
undetectable		 3sufA-1g8kA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 ARG A 822
MET B  93
ARG A 722
 None
 1.45A 3uvvA-1g8kA:
0.0		 3uvvA-1g8kA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1g8k ARSENITE OXIDASE
ARSENITE OXIDASE
(Alcaligenes
faecalis;
Alcaligenes
faecalis) 		3 / 3 THR A 240
ASN A 241
GLU B  97
 F3S  A5005 ( 4.5A)
F3S  A5005 (-4.1A)
None
 0.67A 3v4tA-1g8kA:
0.0
3v4tC-1g8kA:
0.0		 3v4tA-1g8kA:
19.49
3v4tC-1g8kA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 LEU A 574
TYR A 143
LEU A 151
TYR A 578
 None
 0.82A 3v81A-1g8kA:
0.0		 3v81A-1g8kA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 LEU A 574
TYR A 143
LEU A 151
TYR A 578
 None
 0.88A 3v81C-1g8kA:
0.0		 3v81C-1g8kA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 PRO A 303
GLY A 304
ASN A 391
LEU A 683
 None
MGD  A5002 (-3.6A)
None
None
 0.87A 3zqtA-1g8kA:
0.0		 3zqtA-1g8kA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 LEU A 574
TYR A 143
LEU A 151
TYR A 578
 None
 0.75A 4b3qA-1g8kA:
0.0		 4b3qA-1g8kA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 ASN A 750
LEU A 698
GLY A 782
SER A 463
ARG A 193
 None
None
MGD  A5001 ( 4.4A)
None
None
 1.35A 4djfB-1g8kA:
undetectable		 4djfB-1g8kA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 10 SER A 367
ALA A 363
ILE A 274
ILE A 231
LEU A 400
 None
 1.07A 4dt8B-1g8kA:
undetectable		 4dt8B-1g8kA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 GLY A  29
GLY A  27
THR A  20
GLN A 424
VAL A  85
 None
F3S  A5005 (-3.9A)
None
None
None
 1.25A 4f84A-1g8kA:
2.6		 4f84A-1g8kA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ASN A 704
TYR A 727
TYR A 723
LEU A 773
 None
 1.49A 4f8yA-1g8kA:
2.9
4f8yB-1g8kA:
1.3		 4f8yA-1g8kA:
12.61
4f8yB-1g8kA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 9 TRP A 229
GLY A 232
GLY A 386
ILE A 301
PHE A 310
 None
MGD  A5002 (-3.2A)
MGD  A5002 (-3.1A)
None
None
 1.38A 4fgjA-1g8kA:
1.0
4fgjB-1g8kA:
2.0		 4fgjA-1g8kA:
15.34
4fgjB-1g8kA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 GLY A 304
ILE A 352
LEU A 683
PRO A 684
VAL A 687
 MGD  A5002 (-3.6A)
None
None
None
None
 0.71A 4gc9A-1g8kA:
2.8		 4gc9A-1g8kA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 LYS B  74
ILE B  94
THR B  67
 None
 0.82A 4gh8A-1g8kB:
undetectable		 4gh8A-1g8kB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 LEU A 403
LEU A 401
ILE A 387
ILE A 396
LEU A 309
 None
 1.13A 4j26B-1g8kA:
undetectable		 4j26B-1g8kA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 LEU A 244
ASN A 245
LEU A 248
GLN A 252
LEU A  61
 None
 0.99A 4ltwA-1g8kA:
undetectable		 4ltwA-1g8kA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ASP B 101
TYR B  56
LEU B 102
THR B  83
 None
None
None
FES  B5006 (-3.8A)
 1.29A 4paeA-1g8kB:
undetectable		 4paeA-1g8kB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 THR A 503
THR A 511
LEU A 142
SER A 477
 None
 1.07A 4pfjA-1g8kA:
undetectable		 4pfjA-1g8kA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 LEU A 574
TYR A 143
LEU A 151
TYR A 578
 None
 0.88A 4puoC-1g8kA:
0.0		 4puoC-1g8kA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 ARG A 429
ALA A 169
GLY A 171
PHE A 164
GLU A 425
 None
MGD  A5001 ( 4.6A)
None
None
None
 1.24A 4r29C-1g8kA:
0.0		 4r29C-1g8kA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 THR A 453
ILE A 440
LEU A 182
PHE A 160
 None
 0.99A 4r38B-1g8kA:
0.0		 4r38B-1g8kA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 PHE A 752
GLY A 753
SER A 754
GLU A 747
ALA A 468
 None
 1.01A 4u8yB-1g8kA:
0.0		 4u8yB-1g8kA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 PHE A 752
GLY A 753
SER A 754
GLU A 747
ALA A 468
 None
 1.01A 4u95B-1g8kA:
0.0		 4u95B-1g8kA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 PHE A 243
LEU A 244
THR A 281
PHE A 824
 None
None
MGD  A5002 (-4.4A)
None
 0.87A 4wnvD-1g8kA:
0.3		 4wnvD-1g8kA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 CYH A 564
ALA A 562
LEU A 538
ASN A 537
ALA A 601
 None
 1.22A 4x1kA-1g8kA:
undetectable
4x1kB-1g8kA:
undetectable		 4x1kA-1g8kA:
20.26
4x1kB-1g8kA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 179
ALA A 567
LEU A 565
TRP A 595
LEU A 574
 None
 1.00A 4xi3A-1g8kA:
undetectable		 4xi3A-1g8kA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 179
ALA A 567
LEU A 565
TRP A 595
LEU A 574
 None
 0.98A 4xi3B-1g8kA:
undetectable		 4xi3B-1g8kA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 179
ALA A 567
LEU A 565
TRP A 595
LEU A 574
 None
 1.03A 4xi3C-1g8kA:
undetectable		 4xi3C-1g8kA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 179
ALA A 567
LEU A 565
TRP A 595
LEU A 574
 None
 0.99A 4xi3D-1g8kA:
undetectable		 4xi3D-1g8kA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		3 / 3 LEU A 299
ASP A 306
ILE A 273
 None
MGD  A5002 (-3.0A)
None
 0.61A 4xi3D-1g8kA:
undetectable		 4xi3D-1g8kA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 VAL A 496
ILE A 499
LEU A 528
LEU A 526
 None
 1.03A 4xo7A-1g8kA:
undetectable		 4xo7A-1g8kA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 1g8k ARSENITE OXIDASE
ARSENITE OXIDASE
(Alcaligenes
faecalis;
Alcaligenes
faecalis) 		3 / 3 SER B  72
GLU A 764
GLU A 237
 None
 0.64A 4ymgB-1g8kB:
undetectable		 4ymgB-1g8kB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 TRP A 229
GLY A 232
GLY A 386
ILE A 301
PHE A 310
 None
MGD  A5002 (-3.2A)
MGD  A5002 (-3.1A)
None
None
 1.26A 4zvmA-1g8kA:
undetectable
4zvmB-1g8kA:
2.4		 4zvmA-1g8kA:
14.95
4zvmB-1g8kA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 6 ALA B 118
THR B 117
VAL B  11
VAL B  47
 None
 1.04A 5eclA-1g8kB:
undetectable		 5eclA-1g8kB:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 9 PHE A 752
GLY A 753
SER A 754
GLU A 747
ALA A 468
 None
 1.01A 5entC-1g8kA:
undetectable		 5entC-1g8kA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 4 VAL A 496
GLU A 493
GLY A 145
LEU A 142
 None
 1.14A 5g5gC-1g8kA:
0.0		 5g5gC-1g8kA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 5 GLY A 114
THR A 113
GLY A 172
LEU A 515
 None
None
None
MGD  A5001 (-4.0A)
 0.87A 5jlcA-1g8kA:
0.0		 5jlcA-1g8kA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 10 TRP A 229
GLY A 232
GLY A 386
ILE A 301
PHE A 310
 None
MGD  A5002 (-3.2A)
MGD  A5002 (-3.1A)
None
None
 1.21A 5lbtA-1g8kA:
undetectable
5lbtB-1g8kA:
undetectable		 5lbtA-1g8kA:
14.30
5lbtB-1g8kA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 5 VAL A 317
THR A 407
ASN A 409
LEU A 403
 None
 1.06A 5m0iB-1g8kA:
undetectable		 5m0iB-1g8kA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 5 ALA B 118
VAL B 121
PHE B  25
ILE B 125
 None
 0.93A 5of1A-1g8kB:
0.0		 5of1A-1g8kB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 5 ALA B 118
VAL B 121
PHE B  25
ILE B 125
 None
 0.85A 5of1B-1g8kB:
0.0		 5of1B-1g8kB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGG_A_SAMA504_0
(RADICAL SAM DOMAIN
PROTEIN)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 THR A 662
ASN A 217
ARG A 545
VAL A 645
VAL A 655
 None
 1.39A 5wggA-1g8kA:
0.0		 5wggA-1g8kA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 8 ILE A 212
ASN A 409
THR A 332
PHE A 327
 None
 1.02A 5x23A-1g8kA:
0.0		 5x23A-1g8kA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 7 LEU A  58
ARG A   6
THR A   8
LEU A   9
 None
 1.00A 5xdqA-1g8kA:
0.0
5xdqJ-1g8kA:
0.0		 5xdqA-1g8kA:
20.91
5xdqJ-1g8kA:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		5 / 12 LEU A 403
ILE A 231
VAL A 418
LEU A 360
ALA A 363
 None
 1.23A 6djzA-1g8kA:
0.0		 6djzA-1g8kA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 5 GLY A 414
ASP A 221
ARG A 412
ARG A 413
 None
 1.34A 6dwdB-1g8kA:
0.0
6dwdD-1g8kA:
0.0		 6dwdB-1g8kA:
20.43
6dwdD-1g8kA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1g8k ARSENITE OXIDASE
(Alcaligenes
faecalis) 		4 / 5 ARG A 412
ARG A 413
GLY A 414
ASP A 221
 None
 1.31A 6dwjB-1g8kA:
0.0
6dwjD-1g8kA:
0.0		 6dwjB-1g8kA:
20.43
6dwjD-1g8kA:
20.43