SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1g8p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		3 / 3 GLU A  73
ILE A  72
ARG A 260
 None
 0.81A 1cd2A-1g8pA:
0.4		 1cd2A-1g8pA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		3 / 3 GLU A 157
ILE A 160
ARG A 177
 None
 0.66A 1cd2A-1g8pA:
0.4		 1cd2A-1g8pA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 ALA A 272
LEU A 315
LEU A 295
ALA A 298
 None
 0.73A 1e7cA-1g8pA:
0.0		 1e7cA-1g8pA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 THR A  39
VAL A  62
VAL A 213
VAL A  50
 None
 0.92A 1iwiA-1g8pA:
0.0		 1iwiA-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		3 / 3 ILE A 160
LEU A 163
VAL A 167
 None
 0.50A 1mz9B-1g8pA:
0.0		 1mz9B-1g8pA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 LEU A  65
VAL A  62
VAL A 213
VAL A  50
 None
 0.81A 1t86A-1g8pA:
0.0		 1t86A-1g8pA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 THR A  39
VAL A  62
VAL A 213
VAL A  50
 None
 0.75A 1t86A-1g8pA:
0.0		 1t86A-1g8pA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		5 / 9 THR A 293
GLY A 210
ALA A 322
LEU A  34
LEU A 294
 None
 1.27A 2npnA-1g8pA:
undetectable		 2npnA-1g8pA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 5 LEU A  37
ALA A  40
LEU A  69
MET A 250
 None
 1.25A 2oaxA-1g8pA:
undetectable		 2oaxA-1g8pA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 6 LEU A  65
VAL A  62
VAL A 213
VAL A  50
 None
 0.88A 2z97A-1g8pA:
0.0		 2z97A-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 6 THR A  39
VAL A  62
VAL A 213
VAL A  50
 None
 0.95A 2z97A-1g8pA:
0.0		 2z97A-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 LEU A  65
VAL A  62
VAL A 213
VAL A  50
 None
 0.83A 2zujA-1g8pA:
undetectable		 2zujA-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 THR A  39
VAL A  62
VAL A 213
VAL A  50
 None
 0.73A 2zujA-1g8pA:
undetectable		 2zujA-1g8pA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 7 ILE A  26
GLY A  57
VAL A  20
LEU A  36
 None
 0.88A 3elzA-1g8pA:
undetectable		 3elzA-1g8pA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		5 / 12 GLY A  47
GLY A  46
VAL A 107
PRO A 105
VAL A  80
 None
 1.00A 3m6wA-1g8pA:
undetectable		 3m6wA-1g8pA:
26.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		3 / 3 ARG A 260
LEU A 257
GLU A 261
 None
 0.76A 4l3gF-1g8pA:
0.0		 4l3gF-1g8pA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 THR A  39
VAL A  62
VAL A 213
VAL A  50
 None
 0.91A 4l4bA-1g8pA:
0.0		 4l4bA-1g8pA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 LEU A  36
VAL A 106
VAL A 189
TYR A 149
 None
 0.98A 4puoC-1g8pA:
undetectable		 4puoC-1g8pA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 LEU A  36
VAL A 106
VAL A 189
TYR A 149
 None
 0.94A 4pwdA-1g8pA:
undetectable		 4pwdA-1g8pA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 7 ALA A  61
LEU A  36
LEU A  37
ILE A  26
 None
 0.65A 4ubsA-1g8pA:
undetectable		 4ubsA-1g8pA:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 6 GLY A 290
THR A 293
SER A 285
HIS A 325
 None
 1.13A 5ewuA-1g8pA:
0.0		 5ewuA-1g8pA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 6 GLY A 290
THR A 293
SER A 285
HIS A 325
 None
 1.12A 5ewuB-1g8pA:
undetectable		 5ewuB-1g8pA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 4 CYH A 280
LEU A 294
LEU A 323
ALA A 319
 None
 1.11A 5hpuA-1g8pA:
undetectable
5hpuB-1g8pA:
undetectable		 5hpuA-1g8pA:
4.23
5hpuB-1g8pA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 6 PHE A  23
PRO A  22
THR A  60
ILE A  26
 None
 1.22A 5ih0A-1g8pA:
0.0		 5ih0A-1g8pA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		5 / 12 SER A 297
LEU A 295
VAL A 310
HIS A 314
LEU A 315
 None
 1.25A 5ubbA-1g8pA:
undetectable		 5ubbA-1g8pA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		3 / 3 ARG A 246
LYS A  18
TYR A 234
 None
 1.18A 6gnaA-1g8pA:
undetectable		 6gnaA-1g8pA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT
(Rhodobacter
capsulatus) 		3 / 3 ARG A 246
LYS A  18
TYR A 234
 None
 1.18A 6gnbA-1g8pA:
undetectable		 6gnbA-1g8pA:
23.82