SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ga7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 1ga7 HYPOTHETICAL 23.7
KDA PROTEIN IN
ICC-TOLC INTERGENIC
REGION
(Escherichia
coli) 		4 / 8 TRP A 208
GLU A 147
LYS A 122
ARG A 123
 None
 1.00A 4bqfB-1ga7A:
undetectable		 4bqfB-1ga7A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ga7 HYPOTHETICAL 23.7
KDA PROTEIN IN
ICC-TOLC INTERGENIC
REGION
(Escherichia
coli) 		4 / 6 LEU A  63
ASP A  70
GLU A 147
ALA A 153
 None
 0.97A 4nkxA-1ga7A:
0.0		 4nkxA-1ga7A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ga7 HYPOTHETICAL 23.7
KDA PROTEIN IN
ICC-TOLC INTERGENIC
REGION
(Escherichia
coli) 		4 / 8 ALA A 188
ALA A 189
ILE A 192
LEU A 128
 None
 0.51A 4v1fA-1ga7A:
undetectable
4v1fB-1ga7A:
undetectable		 4v1fA-1ga7A:
18.18
4v1fB-1ga7A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1ga7 HYPOTHETICAL 23.7
KDA PROTEIN IN
ICC-TOLC INTERGENIC
REGION
(Escherichia
coli) 		3 / 3 LEU A 204
ASP A  70
ILE A 143
 None
 0.71A 4xi3D-1ga7A:
undetectable		 4xi3D-1ga7A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 1ga7 HYPOTHETICAL 23.7
KDA PROTEIN IN
ICC-TOLC INTERGENIC
REGION
(Escherichia
coli) 		4 / 8 ILE A 185
VAL A 191
GLN A 198
GLU A 181
 None
 1.17A 5dqyA-1ga7A:
undetectable		 5dqyA-1ga7A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1ga7 HYPOTHETICAL 23.7
KDA PROTEIN IN
ICC-TOLC INTERGENIC
REGION
(Escherichia
coli) 		4 / 8 GLU A 116
HIS A 169
GLY A 118
LEU A 119
 None
 0.65A 5w3jB-1ga7A:
undetectable		 5w3jB-1ga7A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1ga7 HYPOTHETICAL 23.7
KDA PROTEIN IN
ICC-TOLC INTERGENIC
REGION
(Escherichia
coli) 		4 / 7 ARG A 110
VAL A  95
PRO A  64
GLY A 146
 None
 0.83A 5x80C-1ga7A:
0.0
5x80D-1ga7A:
0.0		 5x80C-1ga7A:
23.26
5x80D-1ga7A:
23.26