SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gae'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.88A 1c6yA-1gaeO:
undetectable		 1c6yA-1gaeO:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.90A 1c6zB-1gaeO:
undetectable		 1c6zB-1gaeO:
15.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		6 / 7 SER O 148
THR O 150
ASN O 152
CYH O 153
TYR O 311
TYR O 317
 None
None
None
None
None
NAD  O 336 ( 3.9A)
 0.17A 1dssG-1gaeO:
49.8		 1dssG-1gaeO:
65.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		7 / 8 SER O 148
THR O 150
ASN O 152
CYH O 153
HIS O 176
TYR O 311
TYR O 317
 None
None
None
None
None
None
NAD  O 336 ( 3.9A)
 0.29A 1dssR-1gaeO:
49.6		 1dssR-1gaeO:
65.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 TYR O 317
GLY O 120
LEU O 100
MET O 127
 NAD  O 336 ( 3.9A)
NAD  O 336 ( 3.8A)
None
None
 1.24A 1gsfA-1gaeO:
0.3		 1gsfA-1gaeO:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 TYR O 317
GLY O 120
LEU O 100
MET O 127
 NAD  O 336 ( 3.9A)
NAD  O 336 ( 3.8A)
None
None
 1.24A 1gsfB-1gaeO:
undetectable		 1gsfB-1gaeO:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 TYR O 317
GLY O 120
LEU O 100
MET O 127
 NAD  O 336 ( 3.9A)
NAD  O 336 ( 3.8A)
None
None
 1.24A 1gsfD-1gaeO:
0.3		 1gsfD-1gaeO:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.86A 1hxbA-1gaeO:
undetectable		 1hxbA-1gaeO:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.88A 1hxbB-1gaeO:
undetectable		 1hxbB-1gaeO:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.94A 1n49B-1gaeO:
undetectable		 1n49B-1gaeO:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.91A 1n49C-1gaeO:
undetectable		 1n49C-1gaeO:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 PHE O   8
VAL O  66
VAL O  73
ILE O  30
 None
 0.91A 1p7rA-1gaeO:
0.0		 1p7rA-1gaeO:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 PHE O   8
VAL O  66
VAL O  73
ILE O  30
 None
 0.92A 1t87B-1gaeO:
0.0		 1t87B-1gaeO:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.91A 2idwA-1gaeO:
undetectable		 2idwA-1gaeO:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.88A 2o4kB-1gaeO:
undetectable		 2o4kB-1gaeO:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.83A 2q64A-1gaeO:
undetectable		 2q64A-1gaeO:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.88A 2qakA-1gaeO:
undetectable		 2qakA-1gaeO:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 4 ALA O  41
TYR O  42
ALA O  37
TYR O  39
 None
 1.26A 2wlkA-1gaeO:
1.4
2wlkB-1gaeO:
0.0		 2wlkA-1gaeO:
22.13
2wlkB-1gaeO:
22.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		7 / 8 SER O 148
THR O 150
ASN O 152
CYH O 153
HIS O 176
TYR O 311
TYR O 317
 None
None
None
None
None
None
NAD  O 336 ( 3.9A)
 0.30A 3dmtC-1gaeO:
46.6		 3dmtC-1gaeO:
51.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.89A 3ekpD-1gaeO:
undetectable		 3ekpD-1gaeO:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.92A 3ekxB-1gaeO:
undetectable		 3ekxB-1gaeO:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.84A 3el1B-1gaeO:
undetectable		 3el1B-1gaeO:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 TYR O 311
ASN O 222
GLY O 209
ALA O 210
GLY O 215
 None
 0.95A 3hs6B-1gaeO:
0.0		 3hs6B-1gaeO:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.96A 3lzvB-1gaeO:
undetectable		 3lzvB-1gaeO:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.90A 3mwsB-1gaeO:
undetectable		 3mwsB-1gaeO:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.86A 3nu6A-1gaeO:
undetectable		 3nu6A-1gaeO:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.91A 3nujA-1gaeO:
undetectable		 3nujA-1gaeO:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.90A 3oxcA-1gaeO:
undetectable		 3oxcA-1gaeO:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.91A 3tkgD-1gaeO:
undetectable		 3tkgD-1gaeO:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.77A 3tl9B-1gaeO:
undetectable		 3tl9B-1gaeO:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 ILE O 325
SER O 318
THR O  96
VAL O  15
 None
None
NAD  O 336 (-4.4A)
None
 0.80A 3ua5A-1gaeO:
undetectable		 3ua5A-1gaeO:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.85A 4dqbA-1gaeO:
undetectable		 4dqbA-1gaeO:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.96A 4dqfA-1gaeO:
undetectable		 4dqfA-1gaeO:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 6 ALA O 158
GLY O 170
LEU O 242
VAL O 244
 None
 0.90A 4dubB-1gaeO:
undetectable		 4dubB-1gaeO:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 TYR O 311
ASN O 222
GLY O 209
ALA O 210
GLY O 215
 None
 0.87A 4e1gA-1gaeO:
0.0		 4e1gA-1gaeO:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ILE O 325
ILE O  25
ALA O  18
ILE O   5
VAL O   3
 None
 0.90A 4h1nA-1gaeO:
0.0		 4h1nA-1gaeO:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.89A 4njtA-1gaeO:
undetectable		 4njtA-1gaeO:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 6 GLU O 286
THR O 289
THR O 174
HIS O 176
 None
 1.26A 4pfjB-1gaeO:
5.2		 4pfjB-1gaeO:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.91A 4rvjA-1gaeO:
undetectable		 4rvjA-1gaeO:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.92A 4rvjC-1gaeO:
undetectable		 4rvjC-1gaeO:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 THR O 151
ALA O 147
ASN O 152
 None
 0.60A 5ersA-1gaeO:
2.9		 5ersA-1gaeO:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O 294
PHE O 292
GLY O 272
THR O 289
GLU O 264
 None
 1.11A 5hfjA-1gaeO:
undetectable		 5hfjA-1gaeO:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O 294
PHE O 292
GLY O 272
THR O 289
GLU O 264
 None
 1.15A 5hfjC-1gaeO:
undetectable		 5hfjC-1gaeO:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O 294
PHE O 292
GLY O 272
THR O 289
GLU O 264
 None
 1.13A 5hfjG-1gaeO:
undetectable		 5hfjG-1gaeO:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 9 ILE O  30
VAL O 321
LEU O 322
ILE O 325
LEU O  44
 None
 1.08A 5iepA-1gaeO:
0.0		 5iepA-1gaeO:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		6 / 12 VAL O 321
ILE O 325
ALA O 326
VAL O  15
GLY O  12
ILE O  11
 None
None
None
None
None
NAD  O 336 (-3.9A)
 1.36A 5j2tC-1gaeO:
2.4		 5j2tC-1gaeO:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 VAL O 305
LEU O 307
ALA O 299
LEU O 246
 None
 0.59A 5jq7A-1gaeO:
0.0		 5jq7A-1gaeO:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 LYS O   2
LEU O 322
ILE O   5
 None
 0.56A 5kc0A-1gaeO:
0.0		 5kc0A-1gaeO:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA O  19
VAL O   3
ILE O 325
ILE O  11
ILE O  27
 None
None
None
NAD  O 336 (-3.9A)
None
 0.95A 6dh3B-1gaeO:
undetectable		 6dh3B-1gaeO:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ILE O   5
VAL O  73
VAL O  66
ALA O  18
TYR O 317
 None
None
None
None
NAD  O 336 ( 3.9A)
 1.09A 6djzA-1gaeO:
undetectable		 6djzA-1gaeO:
23.55