SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gak'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 1gak FERTILIZATION
PROTEIN
(Haliotis
fulgens) 		4 / 7 ASN A  20
ASP A  23
THR A 131
GLY A 130
 None
 0.77A 2f6dA-1gakA:
undetectable		 2f6dA-1gakA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1gak FERTILIZATION
PROTEIN
(Haliotis
fulgens) 		3 / 3 LEU A  76
PRO A  77
LEU A  71
 None
 0.42A 3hcrA-1gakA:
undetectable		 3hcrA-1gakA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 1gak FERTILIZATION
PROTEIN
(Haliotis
fulgens) 		3 / 3 ARG A  99
PHE A  46
LEU A  40
 None
 0.85A 5veuA-1gakA:
2.2		 5veuA-1gakA:
16.40