SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gdv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 1gdv CYTOCHROME C6
(Pyropia
yezoensis) 		4 / 7 ASN A  42
LEU A  36
LYS A  29
SER A  40
 None
None
HEM  A 101 (-3.3A)
None
 1.41A 3lslA-1gdvA:
undetectable
3lslD-1gdvA:
undetectable		 3lslA-1gdvA:
15.48
3lslD-1gdvA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1gdv CYTOCHROME C6
(Pyropia
yezoensis) 		3 / 3 GLY A  84
GLN A  80
LYS A  33
 None
 0.93A 5imsB-1gdvA:
undetectable		 5imsB-1gdvA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 1gdv CYTOCHROME C6
(Pyropia
yezoensis) 		4 / 4 VAL A   9
GLY A   6
ASP A  72
ASP A   4
 None
 1.44A 6cjkC-1gdvA:
undetectable		 6cjkC-1gdvA:
17.35