SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gff'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 6 HIS 2  58
LEU 2 147
LEU 2  56
PRO 2  29
 None
 1.01A 1hz4A-1gff2:
undetectable		 1hz4A-1gff2:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		3 / 3 ARG 1 382
ILE 1 168
TRP 1 169
 None
 1.04A 1nodB-1gff1:
undetectable		 1nodB-1gff1:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 6 ARG 1 382
ILE 1 168
TRP 1 169
PHE 1 343
 None
 1.48A 1nsiA-1gff1:
0.0
1nsiB-1gff1:
0.0		 1nsiA-1gff1:
20.48
1nsiB-1gff1:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		3 / 3 ARG 1 382
ILE 1 168
TRP 1 169
 None
 1.09A 1qomA-1gff1:
0.0		 1qomA-1gff1:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 8 LEU 2  73
ALA 2  90
ILE 2  91
HIS 2   9
PHE 2 124
 None
 1.39A 1sv9A-1gff2:
undetectable		 1sv9A-1gff2:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		3 / 3 TRP 1 169
ARG 1 382
PHE 1 343
 None
 1.39A 1zeaH-1gff1:
0.3
1zeaL-1gff1:
0.2		 1zeaH-1gff1:
20.88
1zeaL-1gff1:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 7 LEU 2  79
GLY 2  55
PRO 2  83
VAL 2  82
ILE 2 157
 None
 1.43A 2aojB-1gff2:
undetectable		 2aojB-1gff2:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 10 LEU 2  73
ALA 2  90
ILE 2  91
HIS 2   9
PHE 2 124
 None
 1.40A 2b17A-1gff2:
undetectable		 2b17A-1gff2:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		3 / 3 ARG 1 382
ILE 1 168
TRP 1 169
 None
 1.02A 2nodB-1gff1:
undetectable		 2nodB-1gff1:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		3 / 3 SER 2 132
ASP 2 140
ASP 2  63
 None
 0.76A 2plwA-1gff2:
undetectable		 2plwA-1gff2:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 6 SER 1  62
PHE 1 242
ILE 1  66
PHE 1 268
 None
 1.24A 2qeiA-1gff1:
0.0		 2qeiA-1gff1:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 12 THR 1 406
MET 1 404
ILE 1  49
ASN 1 409
ILE 1  66
 None
 1.09A 3a50A-1gff1:
undetectable		 3a50A-1gff1:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 11 THR 1 406
MET 1 404
ILE 1  49
ASN 1 409
ILE 1  66
 None
 1.05A 3a50B-1gff1:
undetectable		 3a50B-1gff1:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 11 THR 1 406
MET 1 404
ILE 1  49
ASN 1 409
ILE 1  66
 None
 1.04A 3a50C-1gff1:
undetectable		 3a50C-1gff1:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 12 THR 1 406
MET 1 404
ILE 1  49
ASN 1 409
ILE 1  66
 None
 1.07A 3a50E-1gff1:
undetectable		 3a50E-1gff1:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 11 THR 1 406
MET 1 404
ILE 1  49
ASN 1 409
ILE 1  66
 None
 1.10A 3a51A-1gff1:
undetectable		 3a51A-1gff1:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 12 THR 1 406
MET 1 404
ILE 1  49
ASN 1 409
ILE 1  66
 None
 1.07A 3a51C-1gff1:
0.0		 3a51C-1gff1:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 12 THR 1 406
MET 1 404
ILE 1  49
ASN 1 409
ILE 1  66
 None
 1.07A 3a51E-1gff1:
undetectable		 3a51E-1gff1:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 12 ILE 1 283
GLY 1 281
ALA 1  37
PHE 1  41
ILE 1  71
 None
 0.92A 3jayA-1gff1:
0.0		 3jayA-1gff1:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4;
Escherichia
virus
G4) 		3 / 3 ASN 2  69
ASN 1 388
GLU 1 154
 None
 0.93A 3kpdC-1gff2:
0.0		 3kpdC-1gff2:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		3 / 3 ARG 1 382
ILE 1 168
TRP 1 169
 None
 1.06A 3nw2B-1gff1:
0.0		 3nw2B-1gff1:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 7 VAL 1 272
PHE 1  41
PHE 1 408
ILE 1  66
 None
 0.96A 3zjqA-1gff1:
undetectable		 3zjqA-1gff1:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 7 VAL 1 272
PHE 1  41
PHE 1 408
ILE 1  66
 None
 0.94A 3zjqB-1gff1:
undetectable		 3zjqB-1gff1:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 6 ALA 1 163
ALA 1 171
PRO 1 172
THR 1 170
 None
 1.13A 4dtzB-1gff1:
undetectable		 4dtzB-1gff1:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 6 PHE 1 343
ARG 1 382
ILE 1 168
TRP 1 169
 None
 1.46A 4nosC-1gff1:
0.0
4nosD-1gff1:
0.0		 4nosC-1gff1:
19.07
4nosD-1gff1:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 11 ILE 2  75
PHE 2 124
ILE 2  91
VAL 2 160
LEU 2 147
 None
 1.28A 5jkwA-1gff2:
undetectable		 5jkwA-1gff2:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 8 ARG 1  26
TRP 1 158
GLU 1 154
ASP 1 391
 None
 1.02A 5kf8A-1gff1:
0.0		 5kf8A-1gff1:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGJ_A_X6XA402_1
(PREDICTED
ACETYLTRANSFERASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 5 ARG 1  26
TRP 1 158
GLU 1 154
ASP 1 391
 None
 1.11A 5kgjA-1gff1:
0.0		 5kgjA-1gff1:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2I_A_LQQA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 4 LYS 1 407
HIS 1 270
VAL 1 272
ASN 1 411
 None
 1.48A 5l2iA-1gff1:
0.0		 5l2iA-1gff1:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		4 / 8 TRP 2 152
THR 2  47
ILE 2 157
PRO 2  83
 None
 1.00A 6a4iA-1gff2:
undetectable		 6a4iA-1gff2:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 12 LEU 1 365
GLY 1 367
SER 1 256
GLN 1 259
ARG 1  55
 None
 1.41A 6bxlB-1gff1:
undetectable		 6bxlB-1gff1:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 12 LEU 1 365
GLY 1 367
SER 1 256
GLN 1 259
ARG 1  55
 None
 1.42A 6bxnB-1gff1:
undetectable		 6bxnB-1gff1:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ
(Escherichia
virus
G4) 		5 / 12 ASP 1 391
GLU 1 392
ASP 1 381
ALA 1 373
SER 1 372
 None
 1.19A 6ew0F-1gff1:
undetectable		 6ew0F-1gff1:
10.37