SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gg3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 1gg3 ERYTHROID MEMBRANE
PROTEIN 4.1R
(Homo
sapiens) 		5 / 11 VAL A 206
GLY A 205
LEU A 204
TYR A 214
GLY A 210
 None
 1.20A 1iolA-1gg3A:
undetectable		 1iolA-1gg3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 1gg3 ERYTHROID MEMBRANE
PROTEIN 4.1R
(Homo
sapiens) 		4 / 6 SER A 121
THR A 123
LEU A 175
ASP A 174
 None
 1.34A 1mxdA-1gg3A:
undetectable		 1mxdA-1gg3A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gg3 ERYTHROID MEMBRANE
PROTEIN 4.1R
(Homo
sapiens) 		5 / 11 GLY A 188
TYR A 187
PHE A 277
PHE A 278
HIS A 274
 None
 1.31A 1w76A-1gg3A:
undetectable		 1w76A-1gg3A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1gg3 ERYTHROID MEMBRANE
PROTEIN 4.1R
(Homo
sapiens) 		5 / 11 PHE A 223
ILE A 254
GLY A 255
ILE A 202
LEU A 204
 None
 0.93A 1z11B-1gg3A:
0.0		 1z11B-1gg3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1gg3 ERYTHROID MEMBRANE
PROTEIN 4.1R
(Homo
sapiens) 		5 / 10 PHE A 223
ILE A 254
GLY A 255
ILE A 202
LEU A 204
 None
 0.99A 1z11C-1gg3A:
0.0		 1z11C-1gg3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1gg3 ERYTHROID MEMBRANE
PROTEIN 4.1R
(Homo
sapiens) 		5 / 10 PHE A 223
ILE A 254
GLY A 255
ILE A 202
LEU A 204
 None
 1.01A 1z11D-1gg3A:
0.0		 1z11D-1gg3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1gg3 ERYTHROID MEMBRANE
PROTEIN 4.1R
(Homo
sapiens) 		4 / 4 ASP A  57
GLY A  23
LYS A  60
GLU A  61
 None
 1.25A 3hznD-1gg3A:
undetectable		 3hznD-1gg3A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1gg3 ERYTHROID MEMBRANE
PROTEIN 4.1R
(Homo
sapiens) 		4 / 8 ASP A  25
ARG A  29
GLU A  32
ASP A  40
 None
 1.12A 6mn4A-1gg3A:
0.0		 6mn4A-1gg3A:
22.44