SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ggp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		4 / 6 LEU A 201
ALA A 217
SER A 193
THR A 218
 None
 1.24A 1tyrA-1ggpA:
0.0		 1tyrA-1ggpA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		5 / 12 THR A 236
ALA A 238
ILE A 227
ILE A 228
LEU A 201
 None
 1.02A 2rlcA-1ggpA:
0.0		 2rlcA-1ggpA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 1ggp PROTEIN (LECTIN 1 B
CHAIN)
(Trichosanthes
kirilowii) 		5 / 12 LEU B  69
ILE B 103
ILE B  97
ILE B  62
VAL B  28
 None
 1.09A 2ygoA-1ggpB:
0.0		 2ygoA-1ggpB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1ggp PROTEIN (LECTIN 1 B
CHAIN)
(Trichosanthes
kirilowii) 		3 / 3 SER B 114
GLY B 135
GLY B  20
 None
 0.56A 3bogA-1ggpB:
0.0
3bogC-1ggpB:
undetectable		 3bogA-1ggpB:
undetectable
3bogC-1ggpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
PROTEIN (LECTIN 1 B
CHAIN)
(Trichosanthes
kirilowii) 		5 / 12 LEU B 123
ALA B  26
GLY B 101
THR A 212
ILE B  62
 None
 1.03A 3c6gA-1ggpB:
undetectable		 3c6gA-1ggpB:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		3 / 3 THR A  53
SER A  65
PHE A  86
 None
 0.90A 3d4sA-1ggpA:
0.0		 3d4sA-1ggpA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		4 / 6 ILE A 127
TYR A 113
MET A 161
ILE A 158
 None
 1.13A 3eteA-1ggpA:
undetectable
3eteE-1ggpA:
undetectable		 3eteA-1ggpA:
20.58
3eteE-1ggpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		4 / 5 ILE A 127
TYR A 113
MET A 161
ILE A 158
 None
 1.13A 3eteB-1ggpA:
undetectable
3eteC-1ggpA:
undetectable		 3eteB-1ggpA:
20.58
3eteC-1ggpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		4 / 7 MET A 161
ILE A 158
ILE A 127
TYR A 113
 None
 1.15A 3eteD-1ggpA:
undetectable
3eteF-1ggpA:
undetectable		 3eteD-1ggpA:
20.58
3eteF-1ggpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NHX_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		5 / 12 SER A  94
PHE A  99
VAL A  66
ASN A 111
ALA A  74
 None
 1.45A 3nhxA-1ggpA:
0.0		 3nhxA-1ggpA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		5 / 12 SER A  94
PHE A  99
VAL A  66
ASN A 111
ALA A  74
 None
 1.49A 3nuvA-1ggpA:
0.0		 3nuvA-1ggpA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		4 / 8 GLY A 130
ILE A 158
ASP A  20
THR A  13
 None
 0.66A 3pwwA-1ggpA:
undetectable		 3pwwA-1ggpA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		4 / 5 ASN A  72
ALA A  74
TYR A  51
ALA A  50
 None
 1.26A 3twpD-1ggpA:
undetectable		 3twpD-1ggpA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1ggp PROTEIN (LECTIN 1 B
CHAIN)
(Trichosanthes
kirilowii) 		3 / 3 ASP B 239
GLU B 241
GLY B 242
 None
 0.63A 3w9tA-1ggpB:
16.4		 3w9tA-1ggpB:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		5 / 12 VAL A 239
ILE A 227
VAL A 229
LEU A 219
VAL A 205
 None
 1.39A 4m11C-1ggpA:
0.0		 4m11C-1ggpA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U3E_A_ACTA705_0
(RIBONUCLEOSIDE
TRIPHOSPHATE
REDUCTASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
PROTEIN (LECTIN 1 B
CHAIN)
(Trichosanthes
kirilowii;
Trichosanthes
kirilowii) 		4 / 4 HIS A  34
ASP B  99
TYR A 233
VAL A 232
 None
 1.12A 4u3eA-1ggpA:
0.0		 4u3eA-1ggpA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		3 / 3 GLU A 164
ALA A 165
PHE A 168
 None
 0.67A 4v1fA-1ggpA:
0.0		 4v1fA-1ggpA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		3 / 3 GLU A 164
ALA A 165
PHE A 168
 None
 0.63A 4v1fC-1ggpA:
undetectable		 4v1fC-1ggpA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1ggp PROTEIN (LECTIN 1 B
CHAIN)
(Trichosanthes
kirilowii) 		5 / 12 ALA B 243
PRO B 259
GLY B 151
SER B 150
SER B 240
 None
 1.31A 5hfjB-1ggpB:
undetectable		 5hfjB-1ggpB:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		5 / 10 SER A 183
ALA A 186
LEU A 129
GLY A 130
LEU A 201
 None
 1.27A 5oy01-1ggpA:
undetectable
5oy07-1ggpA:
undetectable		 5oy01-1ggpA:
15.98
5oy07-1ggpA:
11.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		5 / 6 VAL A  75
TYR A 113
ILE A 159
GLU A 164
ARG A 167
 None
 0.76A 5z3jA-1ggpA:
32.2		 5z3jA-1ggpA:
48.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		5 / 9 LEU A 141
SER A 140
THR A 154
ILE A 158
ILE A 138
 None
 1.05A 6ef6A-1ggpA:
0.3		 6ef6A-1ggpA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1ggp PROTEIN (LECTIN 1 A
CHAIN)
(Trichosanthes
kirilowii) 		5 / 10 SER A 183
ALA A 186
LEU A 129
GLY A 130
LEU A 201
 None
 1.23A 6hqbA-1ggpA:
undetectable
6hqbJ-1ggpA:
0.0		 6hqbA-1ggpA:
16.23
6hqbJ-1ggpA:
11.50