SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ggv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		3 / 3 GLN A 232
THR A 224
TRP A  50
 None
 1.09A 2rctA-1ggvA:
0.0		 2rctA-1ggvA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 7 ALA A 216
ALA A 220
THR A 224
LEU A 164
 None
 0.91A 2wx2A-1ggvA:
undetectable		 2wx2A-1ggvA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 8 ALA A 216
ALA A 220
THR A 224
LEU A 164
 None
 0.92A 2wx2B-1ggvA:
undetectable		 2wx2B-1ggvA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		5 / 12 LEU A  63
GLY A  98
GLY A  96
MET A  93
ALA A 102
 None
 0.96A 3dh0B-1ggvA:
2.4		 3dh0B-1ggvA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 8 ALA A 216
ALA A 220
THR A 224
LEU A 164
 None
 0.80A 3khmA-1ggvA:
undetectable		 3khmA-1ggvA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 8 ALA A 216
ALA A 220
THR A 224
LEU A 164
 None
 0.82A 3l4dA-1ggvA:
undetectable		 3l4dA-1ggvA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 4 LEU A  19
ALA A  58
ILE A  33
LYS A   1
 None
 1.44A 4eixA-1ggvA:
0.0		 4eixA-1ggvA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 5 GLN A 193
HIS A 195
ARG A 223
LEU A 164
 None
 0.94A 4ig5A-1ggvA:
undetectable		 4ig5A-1ggvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 5 GLN A 193
HIS A 195
ARG A 223
LEU A 164
 None
 0.87A 4ig5B-1ggvA:
undetectable		 4ig5B-1ggvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		3 / 3 GLN A 193
HIS A 195
ARG A 223
 None
 0.77A 4qyqA-1ggvA:
undetectable		 4qyqA-1ggvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		3 / 3 GLN A 193
HIS A 195
ARG A 223
 None
 0.69A 4qyqB-1ggvA:
undetectable		 4qyqB-1ggvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		5 / 8 LEU A 119
GLY A 118
VAL A 138
ALA A 133
GLY A 143
 None
 1.18A 4zauA-1ggvA:
undetectable		 4zauA-1ggvA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 5 GLN A 193
HIS A 195
ARG A 223
LEU A 164
 None
 0.84A 5ff1A-1ggvA:
undetectable		 5ff1A-1ggvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 5 GLN A 193
HIS A 195
ARG A 223
LEU A 164
 None
 0.84A 5ff1A-1ggvA:
undetectable		 5ff1A-1ggvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 5 GLN A 193
HIS A 195
ARG A 223
LEU A 164
 None
 0.84A 5ff1B-1ggvA:
0.0		 5ff1B-1ggvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 5 GLN A 193
HIS A 195
ARG A 223
LEU A 164
 None
 0.84A 5ff1B-1ggvA:
0.0		 5ff1B-1ggvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		5 / 12 ARG A 105
VAL A  59
LEU A 119
VAL A 132
GLY A  98
 None
 1.31A 5i8fA-1ggvA:
0.0		 5i8fA-1ggvA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		5 / 12 PHE A 227
ALA A 107
SER A 113
ILE A  31
PRO A  29
 None
 1.39A 5mlmA-1ggvA:
3.0		 5mlmA-1ggvA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		5 / 12 ILE A   8
GLY A  17
VAL A  40
ILE A 104
ALA A 102
 None
 1.11A 5n0xA-1ggvA:
2.7		 5n0xA-1ggvA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		5 / 11 VAL A 147
GLY A 148
GLU A 150
SER A 178
ASP A 171
 SEB  A 123 ( 4.3A)
None
None
None
None
 1.15A 5x6yC-1ggvA:
2.1		 5x6yC-1ggvA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		4 / 6 GLU A  36
TYR A 145
GLY A 168
GLY A 169
 SEB  A 123 ( 4.2A)
SEB  A 123 ( 4.5A)
None
None
 0.75A 5x7pB-1ggvA:
undetectable		 5x7pB-1ggvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 1ggv DIENELACTONE
HYDROLASE
(Pseudomonas
putida) 		5 / 12 PHE A  16
TYR A 122
TYR A 144
LEU A  51
MET A  44
 None
 1.18A 6aycA-1ggvA:
undetectable		 6aycA-1ggvA:
16.02