SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ghf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	1ghf	ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT (Mus musculus)	4 / 4	THR H 118 PRO H 120 THR H 119 PRO H 149	None	1.31A	1dsdC-1ghfH: undetectable	1dsdC-1ghfH: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	1ghf	ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT (Mus musculus)	4 / 4	THR H 119 PRO H 149 THR H 118 PRO H 120	None	1.25A	1dsdC-1ghfH: undetectable	1dsdC-1ghfH: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	1ghf	ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT (Mus musculus)	4 / 4	THR H 118 PRO H 120 THR H 119 PRO H 149	None	1.31A	1dsdC-1ghfH: undetectable	1dsdC-1ghfH: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	1ghf	ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT (Mus musculus)	4 / 4	THR H 119 PRO H 149 THR H 118 PRO H 120	None	1.25A	1dsdC-1ghfH: undetectable	1dsdC-1ghfH: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BPY_A_ACTA408_0 (THIOREDOXIN REDUCTASE)	1ghf	ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT (Mus musculus)	3 / 3	PRO H 186 SER H 187 SER H 188	None	0.68A	6bpyA-1ghfH: undetectable	6bpyA-1ghfH: 21.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","1ghf","ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT","Mus musculus",4,"THR H 118;PRO H 120;THR H 119;PRO H 149","None","1.31A","1dsdC-1ghfH:undetectable","1dsdC-1ghfH:13.33"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","1ghf","ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT","Mus musculus",4,"THR H 119;PRO H 149;THR H 118;PRO H 120","None","1.25A","1dsdC-1ghfH:undetectable","1dsdC-1ghfH:13.33"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","1ghf","ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT","Mus musculus",4,"THR H 118;PRO H 120;THR H 119;PRO H 149","None","1.31A","1dsdC-1ghfH:undetectable","1dsdC-1ghfH:13.33"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","1ghf","ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT","Mus musculus",4,"THR H 119;PRO H 149;THR H 118;PRO H 120","None","1.25A","1dsdC-1ghfH:undetectable","1dsdC-1ghfH:13.33"],["6BPY_A_ACTA408_0","THIOREDOXIN REDUCTASE","1ghf","ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT","Mus musculus",3,"PRO H 186;SER H 187;SER H 188","None","0.68A","6bpyA-1ghfH:undetectable","6bpyA-1ghfH:21.95"]]