SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ghh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1ghh DNA-DAMAGE-INDUCIBLE
PROTEIN I
(Escherichia
coli) 		5 / 12 GLY A  54
ALA A  55
ASP A  59
ILE A  63
GLY A  38
 None
 0.84A 2rkfB-1ghhA:
undetectable		 2rkfB-1ghhA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 1ghh DNA-DAMAGE-INDUCIBLE
PROTEIN I
(Escherichia
coli) 		5 / 12 GLY A  54
ALA A  55
ASP A  59
ILE A  63
GLY A  38
 None
 0.84A 2rkgA-1ghhA:
undetectable		 2rkgA-1ghhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 1ghh DNA-DAMAGE-INDUCIBLE
PROTEIN I
(Escherichia
coli) 		5 / 9 GLY A  54
ALA A  55
ASP A  59
ILE A  63
GLY A  38
 None
 0.95A 3s53A-1ghhA:
undetectable		 3s53A-1ghhA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 1ghh DNA-DAMAGE-INDUCIBLE
PROTEIN I
(Escherichia
coli) 		5 / 11 GLY A  54
ALA A  55
ASP A  59
ILE A  63
GLY A  38
 None
 0.93A 4q1xA-1ghhA:
undetectable		 4q1xA-1ghhA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 1ghh DNA-DAMAGE-INDUCIBLE
PROTEIN I
(Escherichia
coli) 		5 / 10 GLY A  54
ALA A  55
ASP A  59
ILE A  63
GLY A  38
 None
 0.95A 4q1yA-1ghhA:
undetectable		 4q1yA-1ghhA:
24.07