SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ght'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 1ght TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		5 / 12 GLY A   5
ASP A  59
ILE A  93
GLY A  96
LEU A  23
 None
 1.17A 3eeyB-1ghtA:
undetectable		 3eeyB-1ghtA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 1ght TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		5 / 12 GLY A   5
ASP A  59
ILE A  93
GLY A  96
LEU A  23
 None
 1.17A 3eeyC-1ghtA:
undetectable		 3eeyC-1ghtA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 1ght TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		5 / 12 GLY A   5
ASP A  59
ILE A  93
GLY A  96
LEU A  23
 None
 1.12A 3eeyD-1ghtA:
undetectable		 3eeyD-1ghtA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 1ght TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		5 / 12 GLY A   5
ASP A  59
ILE A  93
GLY A  96
LEU A  23
 None
 1.17A 3eeyH-1ghtA:
undetectable		 3eeyH-1ghtA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1ght TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		4 / 5 ILE A  80
THR A  99
SER A  98
PHE A  92
 None
 1.11A 3snfA-1ghtA:
undetectable		 3snfA-1ghtA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1ght TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		5 / 10 ILE A  93
GLY A   5
LEU A  23
ALA A  22
ASP A  25
 None
 1.46A 5ajqB-1ghtA:
undetectable		 5ajqB-1ghtA:
17.41