SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A 178
ARG A  18
ARG A 264
GLN A 211
 None
 1.45A 2vxaA-1gjiA:
0.0
2vxaC-1gjiA:
0.0
2vxaE-1gjiA:
0.0		 2vxaA-1gjiA:
15.60
2vxaC-1gjiA:
15.60
2vxaE-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A  18
ARG A 178
ARG A 264
GLN A 211
 None
 1.43A 2vxaA-1gjiA:
0.0
2vxaB-1gjiA:
0.0
2vxaK-1gjiA:
0.0		 2vxaA-1gjiA:
15.60
2vxaB-1gjiA:
15.60
2vxaK-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A  18
ARG A 178
ARG A 264
GLN A 211
 None
 1.47A 2vxaB-1gjiA:
0.0
2vxaC-1gjiA:
0.0
2vxaG-1gjiA:
0.0		 2vxaB-1gjiA:
15.60
2vxaC-1gjiA:
15.60
2vxaG-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A 178
ARG A  18
ARG A 264
GLN A 211
 None
 1.46A 2vxaD-1gjiA:
0.0
2vxaF-1gjiA:
0.0
2vxaI-1gjiA:
0.0		 2vxaD-1gjiA:
15.60
2vxaF-1gjiA:
15.60
2vxaI-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A  18
ARG A 178
ARG A 264
GLN A 211
 None
 1.40A 2vxaD-1gjiA:
0.0
2vxaE-1gjiA:
0.0
2vxaL-1gjiA:
0.0		 2vxaD-1gjiA:
15.60
2vxaE-1gjiA:
15.60
2vxaL-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A  18
ARG A 178
ARG A 264
GLN A 211
 None
 1.42A 2vxaH-1gjiA:
0.0
2vxaI-1gjiA:
0.0
2vxaJ-1gjiA:
0.0		 2vxaH-1gjiA:
15.60
2vxaI-1gjiA:
15.60
2vxaJ-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A 264
GLN A 211
ARG A 178
ARG A  18
 None
 1.39A 2vxaD-1gjiA:
0.0
2vxaJ-1gjiA:
0.0
2vxaL-1gjiA:
0.0		 2vxaD-1gjiA:
15.60
2vxaJ-1gjiA:
15.60
2vxaL-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A 264
GLN A 211
ARG A  18
ARG A 178
 None
 1.43A 2vxaH-1gjiA:
0.0
2vxaJ-1gjiA:
0.0
2vxaK-1gjiA:
0.0		 2vxaH-1gjiA:
15.60
2vxaJ-1gjiA:
15.60
2vxaK-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 8 ARG A 264
GLN A 211
ARG A  18
ARG A 178
 None
 1.43A 2vxaA-1gjiA:
0.0
2vxaK-1gjiA:
0.0
2vxaL-1gjiA:
0.0		 2vxaA-1gjiA:
15.60
2vxaK-1gjiA:
15.60
2vxaL-1gjiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		5 / 12 ALA A  31
LEU A  78
ILE A 174
LEU A 149
LEU A 104
 None
 1.05A 3k2hA-1gjiA:
undetectable		 3k2hA-1gjiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		5 / 12 GLY A 228
SER A 229
ASP A 201
ILE A 203
VAL A 190
 None
 1.15A 4u8vB-1gjiA:
undetectable		 4u8vB-1gjiA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		3 / 3 SER A 266
ASP A 234
ASP A 213
 None
 0.74A 4uckA-1gjiA:
undetectable		 4uckA-1gjiA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 6 TRP A 224
PRO A 246
ILE A 205
VAL A 190
 None
 0.93A 4zj8A-1gjiA:
undetectable		 4zj8A-1gjiA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		3 / 3 ARG A  23
ILE A 106
PHE A  22
 None
 0.69A 5kirA-1gjiA:
0.0		 5kirA-1gjiA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1gji C-REL PROTO-ONCOGENE
PROTEIN
(Gallus
gallus) 		4 / 7 ILE A 187
VAL A 217
ILE A 203
THR A 245
 None
 0.88A 6cduF-1gjiA:
0.1
6cduG-1gjiA:
1.3		 6cduF-1gjiA:
20.88
6cduG-1gjiA:
20.88