SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gjj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 1gjj LAP2
(Homo
sapiens) 		4 / 5 THR A  46
LEU A 149
GLY A 153
TYR A 127
 None
 1.39A 1gtiF-1gjjA:
undetectable		 1gtiF-1gjjA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 1gjj LAP2
(Homo
sapiens) 		4 / 5 LEU A  40
GLN A  32
LEU A  27
GLU A  31
 None
 0.89A 3h5gA-1gjjA:
undetectable
3h5gB-1gjjA:
undetectable		 3h5gA-1gjjA:
12.90
3h5gB-1gjjA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 1gjj LAP2
(Homo
sapiens) 		4 / 5 GLN A  32
ILE A 134
TYR A 142
GLU A 143
 None
 1.23A 4a99D-1gjjA:
undetectable		 4a99D-1gjjA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1gjj LAP2
(Homo
sapiens) 		4 / 6 GLU A  19
LEU A  11
LEU A  45
LEU A 146
 None
 0.97A 5yvnA-1gjjA:
undetectable		 5yvnA-1gjjA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1gjj LAP2
(Homo
sapiens) 		4 / 6 GLU A  19
LEU A 115
LEU A  45
LEU A 146
 None
 0.93A 5yvnA-1gjjA:
undetectable		 5yvnA-1gjjA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1gjj LAP2
(Homo
sapiens) 		5 / 10 LEU A  20
TYR A  41
PRO A   8
GLU A 114
SER A   9
 None
 1.43A 6b89A-1gjjA:
undetectable		 6b89A-1gjjA:
19.11