SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 LEU A 335
HIS A 327
GLU A 329
ASP A 346
GLY A 355
 None
 1.35A 1d4fA-1gjuA:
undetectable		 1d4fA-1gjuA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 LEU A 335
HIS A 327
GLU A 329
ASP A 346
GLY A 355
 None
 1.29A 1d4fD-1gjuA:
0.4		 1d4fD-1gjuA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 SER A 156
GLN A 312
TRP A 315
GLU A 414
ASN A 512
 None
 1.18A 1eswA-1gjuA:
20.6		 1eswA-1gjuA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 SER A 156
TYR A 158
GLN A 312
TRP A 315
ASN A 512
 None
 0.85A 1eswA-1gjuA:
20.6		 1eswA-1gjuA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 LEU A 268
PRO A 269
LEU A 272
 None
 0.55A 1hrkA-1gjuA:
undetectable		 1hrkA-1gjuA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 5 ARG A  40
ASP A 529
SER A 526
SER A 547
 None
 1.38A 1kiaB-1gjuA:
2.6		 1kiaB-1gjuA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 6 ARG A  40
ASP A 529
SER A 526
SER A 547
 None
 1.39A 1kiaC-1gjuA:
undetectable		 1kiaC-1gjuA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 7 LEU A  25
LEU A 125
TYR A  97
LEU A 543
 None
 1.10A 1kt3A-1gjuA:
undetectable		 1kt3A-1gjuA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 5 LEU A 200
VAL A 198
ALA A 190
CYH A 191
 None
 1.14A 1mz9D-1gjuA:
0.0		 1mz9D-1gjuA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 7 TYR A 373
VAL A 142
VAL A 180
ASP A 181
 None
 0.93A 1p7rA-1gjuA:
0.0		 1p7rA-1gjuA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 THR A 118
LEU A 125
LEU A 126
ILE A   6
GLY A  49
 None
 0.86A 1qknA-1gjuA:
undetectable		 1qknA-1gjuA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 LEU A 175
LEU A 174
TYR A  20
LEU A 124
ILE A   6
 None
 1.10A 1s9pD-1gjuA:
undetectable		 1s9pD-1gjuA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 ALA A 536
VAL A 542
TRP A 545
 None
 0.89A 1tkqB-1gjuA:
undetectable		 1tkqB-1gjuA:
2.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 5 GLN A 503
TRP A 437
GLU A 465
LEU A 521
 None
 1.49A 1ulvA-1gjuA:
3.6		 1ulvA-1gjuA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 LEU A 335
HIS A 327
GLU A 329
ASP A 346
GLY A 355
 None
 1.32A 1v8bC-1gjuA:
undetectable		 1v8bC-1gjuA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 TRP A 545
THR A 501
TYR A  87
 None
 1.25A 2a3aA-1gjuA:
6.0		 2a3aA-1gjuA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 TRP A 545
THR A 501
TYR A  87
 None
 1.23A 2a3aB-1gjuA:
5.2		 2a3aB-1gjuA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 TRP A 545
THR A 501
TYR A  87
 None
 1.23A 2a3bA-1gjuA:
9.7		 2a3bA-1gjuA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 7 TYR A 373
VAL A 142
VAL A 180
ASP A 181
 None
 0.98A 2cppA-1gjuA:
0.0		 2cppA-1gjuA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 PRO A 340
THR A 267
PRO A 269
 None
 0.83A 2d55C-1gjuA:
undetectable		 2d55C-1gjuA:
2.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 TRP A 315
LYS A 151
PRO A 313
 None
 1.24A 2dqyB-1gjuA:
0.7		 2dqyB-1gjuA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 11 ASN A 500
VAL A 499
ILE A 496
TYR A 490
ASP A 201
 None
 1.49A 2iyfA-1gjuA:
0.9		 2iyfA-1gjuA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 9 GLY A 611
ILE A 608
THR A 579
VAL A 596
ILE A 597
 None
 1.31A 2nnhB-1gjuA:
0.0		 2nnhB-1gjuA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 11 SER A 156
TYR A 158
GLN A 312
TRP A 315
ASN A 512
 None
 0.97A 2owcA-1gjuA:
20.4		 2owcA-1gjuA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 THR A  53
ILE A   6
TYR A   9
GLY A  49
LEU A 124
 None
 1.10A 2y7kD-1gjuA:
undetectable		 2y7kD-1gjuA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 8 ALA A 536
MET A 511
LEU A 543
GLY A 502
 None
 0.51A 2yfxA-1gjuA:
undetectable		 2yfxA-1gjuA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 PRO A  91
GLU A 183
TYR A 170
 None
 0.72A 2zmbA-1gjuA:
0.0		 2zmbA-1gjuA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 PHE A 439
LEU A 559
PRO A 497
ILE A 452
ASP A 451
 None
 1.33A 2zznB-1gjuA:
undetectable		 2zznB-1gjuA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 10 MET A 164
LEU A 321
LEU A 366
VAL A 369
ILE A 203
 None
 1.10A 3fl9E-1gjuA:
undetectable		 3fl9E-1gjuA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 LYS A 403
ILE A 432
PHE A 460
 None
 0.88A 3j7zS-1gjuA:
0.0
3j7za-1gjuA:
undetectable		 3j7zS-1gjuA:
10.20
3j7za-1gjuA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 11 MET A 164
LEU A 321
LEU A 366
VAL A 369
ILE A 203
 None
 1.08A 3jw5A-1gjuA:
undetectable		 3jw5A-1gjuA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 10 MET A 164
LEU A 321
LEU A 366
VAL A 369
ILE A 203
 None
 1.12A 3jw5B-1gjuA:
undetectable		 3jw5B-1gjuA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 VAL A 410
TYR A 429
GLY A 381
PHE A 202
TYR A 138
 None
 1.30A 3mecA-1gjuA:
undetectable		 3mecA-1gjuA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 VAL A 410
TYR A 429
GLY A 381
PHE A 202
TYR A 138
 None
 1.32A 3medA-1gjuA:
0.0
3medB-1gjuA:
0.1		 3medA-1gjuA:
22.53
3medB-1gjuA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 VAL A 431
VAL A  86
SER A  84
 None
 0.74A 3n8xB-1gjuA:
0.0		 3n8xB-1gjuA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 PHE A 128
ILE A 556
LEU A 553
GLY A 133
ALA A 134
 None
 0.87A 3rukB-1gjuA:
undetectable		 3rukB-1gjuA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 SER A 143
ASP A 147
ASP A 153
 None
 0.91A 3uj7A-1gjuA:
undetectable		 3uj7A-1gjuA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GCP_A_AICA401_1
(OUTER MEMBRANE
PROTEIN F)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 9 TYR A 498
TYR A 138
GLY A  88
ASP A 201
ARG A  92
 None
 1.48A 4gcpA-1gjuA:
0.0		 4gcpA-1gjuA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GCP_B_AICB401_1
(OUTER MEMBRANE
PROTEIN F)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 9 TYR A 498
TYR A 138
GLY A  88
ASP A 201
ARG A  92
 None
 1.48A 4gcpB-1gjuA:
0.0		 4gcpB-1gjuA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 8 VAL A 198
LEU A 139
LEU A 200
ASP A 181
 None
 0.78A 4lzrA-1gjuA:
undetectable		 4lzrA-1gjuA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 8 TYR A 490
ILE A 556
ILE A 560
ALA A 134
 None
 0.88A 4ou1A-1gjuA:
10.2		 4ou1A-1gjuA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 8 GLU A  12
LEU A   3
LEU A 175
GLY A  49
 None
 0.76A 4r3aA-1gjuA:
undetectable		 4r3aA-1gjuA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 5 GLU A 329
LYS A 332
ASP A 326
GLU A 357
 None
 1.19A 5a06A-1gjuA:
1.3		 5a06A-1gjuA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 ARG A 322
PRO A 269
ASN A 271
 None
 0.90A 5jwaA-1gjuA:
0.0
5jwaH-1gjuA:
0.0		 5jwaA-1gjuA:
23.01
5jwaH-1gjuA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 LEU A 175
GLY A  49
ASN A   7
LEU A   3
ALA A 186
 None
 1.39A 5kbwA-1gjuA:
0.0		 5kbwA-1gjuA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 LEU A 175
GLY A  49
LEU A   3
ALA A 186
PHE A 178
 None
 1.24A 5kc4E-1gjuA:
undetectable		 5kc4E-1gjuA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 10 PRO A 302
ILE A 299
ILE A 224
TRP A 223
THR A 319
 None
 1.38A 5mvnD-1gjuA:
0.0		 5mvnD-1gjuA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 7 GLY A 381
ASP A 406
HIS A 192
ASP A 380
 None
 1.03A 5nnwD-1gjuA:
undetectable		 5nnwD-1gjuA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		4 / 7 GLY A 381
ASP A 406
HIS A 192
ASP A 380
 None
 0.99A 5no9D-1gjuA:
undetectable		 5no9D-1gjuA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 ILE A  19
PHE A 113
PHE A 120
THR A  15
PRO A  45
 None
 0.99A 5xxiA-1gjuA:
0.0		 5xxiA-1gjuA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 ILE A 452
LEU A 433
PRO A 486
THR A 489
LEU A 449
 None
 1.23A 5xxiA-1gjuA:
0.0		 5xxiA-1gjuA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 10 SER A  89
GLY A  88
ILE A 196
ALA A 134
LEU A 132
 None
 1.41A 5zjiA-1gjuA:
undetectable
5zjiJ-1gjuA:
0.0		 5zjiA-1gjuA:
8.03
5zjiJ-1gjuA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 PHE A 320
GLY A 303
ILE A 214
LEU A 213
ALA A 208
 None
 1.08A 6c2mA-1gjuA:
undetectable		 6c2mA-1gjuA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		5 / 12 LEU A 433
LEU A 461
GLY A 381
ARG A 197
PRO A 459
 None
 1.14A 6ce2B-1gjuA:
undetectable		 6ce2B-1gjuA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE
(Thermotoga
maritima) 		3 / 3 GLY A 428
ASP A 430
ILE A 412
 None
 0.62A 6dgxB-1gjuA:
0.0		 6dgxB-1gjuA:
8.13