SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gka'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1gka CRUSTACYANIN A2
SUBUNIT
(Homarus
gammarus) 		5 / 12 PHE B  60
ALA B  27
SER B 114
THR B 108
ASP B  22
 None
 1.25A 2qm9A-1gkaB:
3.0		 2qm9A-1gkaB:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1gka CRUSTACYANIN A2
SUBUNIT
(Homarus
gammarus) 		4 / 6 THR B 108
PHE B  21
PHE B  60
TYR B  51
 None
 1.11A 3elzB-1gkaB:
3.2		 3elzB-1gkaB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1gka CRUSTACYANIN A2
SUBUNIT
(Homarus
gammarus) 		5 / 11 SER B  49
PHE B 133
ILE B  93
VAL B  43
VAL B 164
 None
None
AXT  B1175 (-4.7A)
None
None
 1.00A 3w67A-1gkaB:
undetectable		 3w67A-1gkaB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1gka CRUSTACYANIN A2
SUBUNIT
(Homarus
gammarus) 		5 / 12 VAL B  62
SER B  49
PHE B 133
VAL B  43
VAL B 164
 None
 1.07A 3w68A-1gkaB:
undetectable		 3w68A-1gkaB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1gka CRUSTACYANIN A2
SUBUNIT
(Homarus
gammarus) 		5 / 12 VAL B  62
PHE B 133
ILE B  93
VAL B  43
VAL B 164
 None
None
AXT  B1175 (-4.7A)
None
None
 1.04A 3w68D-1gkaB:
undetectable		 3w68D-1gkaB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1gka CRUSTACYANIN A2
SUBUNIT
(Homarus
gammarus) 		3 / 3 THR B  83
MET B  91
HIS B  90
 None
 0.98A 5uunA-1gkaB:
0.0		 5uunA-1gkaB:
18.67