SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gke'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 12 ILE A 107
LEU A 111
LEU A  55
VAL A  30
ALA A  29
 None
 1.16A 1axwA-1gkeA:
0.0		 1axwA-1gkeA:
19.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 8 LEU A  17
LEU A 110
SER A 117
THR A 119
 None
 0.28A 1dvtA-1gkeA:
22.1
1dvtB-1gkeA:
21.1		 1dvtA-1gkeA:
84.62
1dvtB-1gkeA:
84.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 115
SER A 117
 None
 0.82A 1dvxA-1gkeA:
22.2		 1dvxA-1gkeA:
84.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 115
THR A 119
 None
 0.53A 1dvxA-1gkeA:
22.2		 1dvxA-1gkeA:
84.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.72A 1dvxB-1gkeA:
21.1		 1dvxB-1gkeA:
84.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LEU A  17
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.37A 1dvxB-1gkeA:
21.1		 1dvxB-1gkeA:
84.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 7 LYS A  15
ALA A 108
THR A 119
VAL A 121
 None
 0.80A 1dvxB-1gkeA:
21.1		 1dvxB-1gkeA:
84.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 5 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.61A 1eta1-1gkeA:
21.7		 1eta1-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 5 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.52A 1eta2-1gkeA:
20.3		 1eta2-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.61A 1etb1-1gkeA:
22.5		 1etb1-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
 None
 0.56A 1etb2-1gkeA:
21.2		 1etb2-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 6 LYS A  15
GLU A  54
THR A 106
ALA A 108
 None
 0.54A 1etb2-1gkeA:
21.2		 1etb2-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 11 LEU A  17
GLU A  54
ALA A 108
LEU A 110
SER A 117
 None
 0.86A 1ictA-1gkeA:
22.0
1ictC-1gkeA:
21.7		 1ictA-1gkeA:
83.33
1ictC-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 11 LEU A  17
GLU A  54
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.58A 1ictA-1gkeA:
22.0
1ictC-1gkeA:
21.7		 1ictA-1gkeA:
83.33
1ictC-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.64A 1ictB-1gkeA:
21.8		 1ictB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LEU A  17
THR A 106
LEU A 110
THR A 119
VAL A 121
 None
 0.46A 1ictD-1gkeA:
21.9		 1ictD-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 10 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.68A 1ie4A-1gkeA:
22.9
1ie4C-1gkeA:
22.5		 1ie4A-1gkeA:
100.00
1ie4C-1gkeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 8 LYS A  15
GLU A  54
ALA A 108
THR A 119
 None
 0.50A 1ie4B-1gkeA:
22.5
1ie4D-1gkeA:
22.6		 1ie4B-1gkeA:
100.00
1ie4D-1gkeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 7 LYS A  15
LEU A  17
GLU A  54
ALA A 108
 None
 0.51A 1sn0B-1gkeA:
20.2
1sn0D-1gkeA:
19.9		 1sn0B-1gkeA:
56.92
1sn0D-1gkeA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 6 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
VAL A 121
 None
 0.60A 1sn5A-1gkeA:
19.7		 1sn5A-1gkeA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		7 / 8 LYS A  15
LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.66A 1sn5C-1gkeA:
19.6		 1sn5C-1gkeA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 12 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
VAL A 121
 None
 0.60A 1sn5B-1gkeA:
20.2
1sn5D-1gkeA:
19.9		 1sn5B-1gkeA:
56.92
1sn5D-1gkeA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 12 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
VAL A 121
 None
 0.62A 1sn5B-1gkeA:
20.2
1sn5D-1gkeA:
19.9		 1sn5B-1gkeA:
56.92
1sn5D-1gkeA:
56.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		3 / 3 LEU A  17
LEU A 110
SER A 117
 None
 0.60A 1tlmA-1gkeA:
22.3		 1tlmA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 4 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 0.48A 1tt6A-1gkeA:
21.0		 1tt6A-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.48A 1tt6B-1gkeA:
21.9		 1tt6B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.31A 1tyrA-1gkeA:
21.7		 1tyrA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.64A 1tyrB-1gkeA:
20.5		 1tyrB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LEU A  17
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.35A 1tyrB-1gkeA:
20.5		 1tyrB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 7 LYS A  15
THR A 106
ALA A 108
VAL A 121
 None
 0.45A 1tyrB-1gkeA:
20.5		 1tyrB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 11 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.76A 1tz8A-1gkeA:
21.6
1tz8B-1gkeA:
21.8		 1tz8A-1gkeA:
83.33
1tz8B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 11 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.75A 1tz8A-1gkeA:
21.6
1tz8B-1gkeA:
21.8		 1tz8A-1gkeA:
83.33
1tz8B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.27A 1tz8C-1gkeA:
22.0
1tz8D-1gkeA:
22.0		 1tz8C-1gkeA:
83.33
1tz8D-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 4 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.73A 2roxA-1gkeA:
22.2		 2roxA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LEU A  17
GLU A  54
ALA A 108
LEU A 110
THR A 119
 None
 0.57A 2roxB-1gkeA:
21.0		 2roxB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LYS A  15
GLU A  54
ALA A 108
LEU A 110
THR A 119
 None
 0.64A 2roxB-1gkeA:
21.0		 2roxB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.62A 3cfqA-1gkeA:
22.1		 3cfqA-1gkeA:
83.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.62A 3cfqA-1gkeA:
22.1
3cfqB-1gkeA:
21.0		 3cfqA-1gkeA:
83.05
3cfqB-1gkeA:
83.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		7 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.68A 3d2tA-1gkeA:
22.1		 3d2tA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 6 LYS A  15
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.69A 3d2tB-1gkeA:
20.7		 3d2tB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		7 / 9 MET A  13
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.57A 3ozkA-1gkeA:
22.0		 3ozkA-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 9 MET A  13
LYS A  15
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
 0.73A 3ozkA-1gkeA:
22.0		 3ozkA-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.59A 3ozkB-1gkeA:
21.4		 3ozkB-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.31A 4d7bB-1gkeA:
22.3		 4d7bB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
SER A 117
THR A 119
 None
 0.68A 4d7bB-1gkeA:
22.3		 4d7bB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.79A 4d7bA-1gkeA:
22.0		 4d7bA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
 None
 0.81A 4d7bA-1gkeA:
22.0		 4d7bA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.28A 4i89A-1gkeA:
22.1		 4i89A-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I89_B_1FLB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 4 LYS A  15
ALA A 108
SER A 117
THR A 119
 None
 0.86A 4i89B-1gkeA:
21.0		 4i89B-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		3 / 3 LYS A  15
LEU A  17
ALA A 108
 None
 0.77A 4iizA-1gkeA:
21.1		 4iizA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		8 / 8 MET A  13
LYS A  15
LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.81A 4iizB-1gkeA:
20.2		 4iizB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK6_A_LURA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 4 LYS A  15
LEU A  17
ALA A 108
VAL A 121
 None
 0.84A 4ik6A-1gkeA:
21.2		 4ik6A-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 8 MET A  13
LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
 None
 0.73A 4ik6B-1gkeA:
20.3		 4ik6B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 8 MET A  13
LEU A  17
GLU A  54
THR A 106
ALA A 108
VAL A 121
 None
 0.69A 4ik6B-1gkeA:
20.3		 4ik6B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 8 MET A  13
LYS A  15
LEU A  17
GLU A  54
THR A 106
ALA A 108
 None
 0.83A 4ik6B-1gkeA:
20.3		 4ik6B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		7 / 7 MET A  13
LYS A  15
LEU A  17
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
 0.71A 4ik7A-1gkeA:
21.5		 4ik7A-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 8 LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.51A 4ik7B-1gkeA:
20.4		 4ik7B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 8 LYS A  15
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
 0.59A 4ik7B-1gkeA:
20.4		 4ik7B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.76A 4ikiB-1gkeA:
21.0		 4ikiB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.63A 4ikiB-1gkeA:
21.0		 4ikiB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.67A 4ikjA-1gkeA:
21.6
4ikjB-1gkeA:
20.4		 4ikjA-1gkeA:
83.33
4ikjB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 8 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.69A 4ikjA-1gkeA:
21.6
4ikjB-1gkeA:
20.4		 4ikjA-1gkeA:
83.33
4ikjB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 8 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.73A 4ikkA-1gkeA:
21.2
4ikkB-1gkeA:
20.3		 4ikkA-1gkeA:
83.33
4ikkB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 8 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.56A 4ikkA-1gkeA:
21.2
4ikkB-1gkeA:
20.3		 4ikkA-1gkeA:
83.33
4ikkB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 7 LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.37A 4ikkA-1gkeA:
21.2
4ikkB-1gkeA:
20.3		 4ikkA-1gkeA:
83.33
4ikkB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 7 LYS A  15
LEU A  17
ALA A 108
THR A 119
 None
 0.73A 4ikkA-1gkeA:
21.2
4ikkB-1gkeA:
20.3		 4ikkA-1gkeA:
83.33
4ikkB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.51A 4iklA-1gkeA:
22.0
4iklB-1gkeA:
21.1		 4iklA-1gkeA:
83.33
4iklB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 8 LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.40A 4iklA-1gkeA:
22.0
4iklB-1gkeA:
21.1		 4iklA-1gkeA:
83.33
4iklB-1gkeA:
83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 9 TYR A  78
THR A  49
GLY A  53
LEU A  55
VAL A  14
 None
 1.22A 4mjrA-1gkeA:
undetectable		 4mjrA-1gkeA:
15.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 6 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
 None
 0.48A 4pwjA-1gkeA:
22.1		 4pwjA-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 7 LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.41A 4pwjB-1gkeA:
21.7		 4pwjB-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 7 LYS A  15
THR A 106
ALA A 108
SER A 117
THR A 119
 None
 0.54A 4pwjB-1gkeA:
21.7		 4pwjB-1gkeA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		3 / 3 SER A  46
ALA A  29
VAL A  28
 None
 0.54A 4x20C-1gkeA:
undetectable		 4x20C-1gkeA:
13.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.74A 5a6iA-1gkeA:
21.3		 5a6iA-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
VAL A 121
 None
 0.47A 5a6iA-1gkeA:
21.3		 5a6iA-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 6 LYS A  15
LEU A  17
ALA A 108
VAL A 121
 None
 0.63A 5a6iA-1gkeA:
21.3		 5a6iA-1gkeA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		6 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.50A 5bojA-1gkeA:
22.1		 5bojA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		7 / 7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.51A 5bojB-1gkeA:
21.2		 5bojB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
VAL A 121
 None
 0.62A 5cr1A-1gkeA:
21.9		 5cr1A-1gkeA:
83.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 12 VAL A 121
ALA A 108
LEU A  17
GLY A  53
THR A  49
 None
 1.19A 5igpA-1gkeA:
undetectable		 5igpA-1gkeA:
18.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.32A 5l4iA-1gkeA:
22.1		 5l4iA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
SER A 117
THR A 119
 None
 0.84A 5l4iA-1gkeA:
22.1		 5l4iA-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		5 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.31A 5l4iB-1gkeA:
21.2		 5l4iB-1gkeA:
83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 8 VAL A  71
VAL A  32
LEU A  58
THR A  59
 None
 0.85A 5tt3F-1gkeA:
undetectable		 5tt3F-1gkeA:
17.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 4 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.62A 6gnrA-1gkeA:
19.9		 6gnrA-1gkeA:
54.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 1gke TRANSTHYRETIN
(Rattus
norvegicus) 		4 / 4 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.60A 6gnrB-1gkeA:
19.9		 6gnrB-1gkeA:
54.81