SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gl9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 9 LEU B 780
THR B 794
ILE B 797
THR B 808
ILE B 807
 None
 1.40A 1hzeA-1gl9B:
0.0
1hzeB-1gl9B:
0.0		 1hzeA-1gl9B:
6.74
1hzeB-1gl9B:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 9 THR B 808
ILE B 807
LEU B 780
THR B 794
ILE B 797
 None
 1.39A 1hzeA-1gl9B:
0.0
1hzeB-1gl9B:
0.0		 1hzeA-1gl9B:
6.74
1hzeB-1gl9B:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 VAL B 479
ASP B 477
SER B 475
THR B 436
ARG B 344
 None
 1.28A 1ia0B-1gl9B:
undetectable		 1ia0B-1gl9B:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 THR B 662
PHE B 658
PHE B 509
GLU B 668
 None
 1.08A 1icuA-1gl9B:
0.0
1icuB-1gl9B:
0.0		 1icuA-1gl9B:
13.06
1icuB-1gl9B:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 THR B 662
PHE B 658
PHE B 509
GLU B 668
 None
 1.02A 1kqbA-1gl9B:
0.0
1kqbB-1gl9B:
0.0		 1kqbA-1gl9B:
12.44
1kqbB-1gl9B:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 THR B 662
PHE B 658
PHE B 509
GLU B 668
 None
 1.04A 1kqbC-1gl9B:
0.0
1kqbD-1gl9B:
0.0		 1kqbC-1gl9B:
12.44
1kqbD-1gl9B:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 PHE B 509
GLU B 668
THR B 662
PHE B 658
 None
 1.04A 1kqbC-1gl9B:
0.0
1kqbD-1gl9B:
0.0		 1kqbC-1gl9B:
12.44
1kqbD-1gl9B:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 GLU B 803
ASN B 804
GLY B 871
ILE B 666
SER B 513
 None
 0.98A 1q8jB-1gl9B:
undetectable		 1q8jB-1gl9B:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 ARG B 982
ASP B 558
TYR B 578
ASP B 642
 None
 1.28A 1rjdB-1gl9B:
3.0		 1rjdB-1gl9B:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 11 HIS B 876
SER B 790
PHE B 789
ILE B 797
GLU B 875
 None
 1.46A 1rnrA-1gl9B:
undetectable		 1rnrA-1gl9B:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 VAL B 479
ASP B 477
SER B 475
THR B 436
ARG B 344
 None
 1.28A 1tubB-1gl9B:
undetectable		 1tubB-1gl9B:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		3 / 3 THR B 850
GLU B 668
HIS B 659
 None
 0.92A 1xwfA-1gl9B:
1.7		 1xwfA-1gl9B:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 8 LEU B  89
ILE B 160
ILE B 119
ARG B 120
ILE B 134
 None
 1.12A 2bu8A-1gl9B:
undetectable		 2bu8A-1gl9B:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 8 SER B 528
PHE B 242
LEU B 220
ASP B 185
 None
 1.17A 2bxkA-1gl9B:
0.8		 2bxkA-1gl9B:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU B 426
VAL B 414
ALA B 461
LEU B 458
SER B 353
 None
 1.15A 2c12C-1gl9B:
0.0		 2c12C-1gl9B:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 11 LEU B 426
VAL B 414
ALA B 461
LEU B 458
SER B 353
 None
 1.19A 2c12F-1gl9B:
1.5		 2c12F-1gl9B:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_A_SAMA801_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 10 GLU B 660
GLY B 805
LEU B 806
HIS B 659
TYR B 809
 None
 1.40A 2h21A-1gl9B:
undetectable		 2h21A-1gl9B:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 11 GLU B 660
GLY B 805
LEU B 806
HIS B 659
TYR B 809
 None
 1.37A 2h21B-1gl9B:
undetectable		 2h21B-1gl9B:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 11 GLU B 660
GLY B 805
LEU B 806
HIS B 659
TYR B 809
 None
 1.36A 2h21C-1gl9B:
undetectable		 2h21C-1gl9B:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 GLU B 539
VAL B 537
LEU B 532
ALA B  75
PHE B  74
 None
 1.23A 2jj8C-1gl9B:
undetectable		 2jj8C-1gl9B:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 8 ASP B 622
GLU B 624
HIS B 621
LEU B  43
 None
 1.05A 2q0iA-1gl9B:
undetectable		 2q0iA-1gl9B:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 VAL B 858
PHE B 884
PRO B 849
THR B 850
 None
 1.34A 2q6oB-1gl9B:
undetectable		 2q6oB-1gl9B:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 ARG B 816
GLU B 845
GLN B 891
PRO B 773
 None
 0.94A 2qqtA-1gl9B:
undetectable		 2qqtA-1gl9B:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 8 ILE B 187
LEU B 220
LEU B 240
PHE B 236
 None
 0.91A 2vctC-1gl9B:
0.0		 2vctC-1gl9B:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 7 PHE B 509
ALA B 669
LEU B 667
PHE B 524
 None
 1.16A 2vcvA-1gl9B:
0.0		 2vcvA-1gl9B:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 4 VAL B 820
ASP B 470
LEU B 867
ARG B 848
 None
 1.46A 2ziaA-1gl9B:
undetectable		 2ziaA-1gl9B:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		3 / 3 ARG B 968
GLU B 777
ASP B 782
 None
 0.68A 3g2oA-1gl9B:
5.0		 3g2oA-1gl9B:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 ARG B 816
GLU B 845
GLN B 891
PRO B 773
 None
 0.97A 3gclA-1gl9B:
0.0		 3gclA-1gl9B:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP B 477
PHE B 481
SER B 449
 None
 0.98A 3i5uB-1gl9B:
undetectable		 3i5uB-1gl9B:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 10 PHE B 789
SER B 790
ALA B 798
LEU B 879
ALA B 783
 None
 1.43A 3lw5B-1gl9B:
0.0		 3lw5B-1gl9B:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 7 ALA B 889
TYR B 927
ARG B 928
ALA B 929
 None
 1.11A 3twpC-1gl9B:
undetectable		 3twpC-1gl9B:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 7 ILE B 179
PHE B 236
PHE B 242
LEU B 240
 None
 0.88A 3v7pA-1gl9B:
0.2		 3v7pA-1gl9B:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 TYR B1047
GLY B 564
GLY B 567
LEU B 559
TYR B 578
 None
 1.03A 3vywA-1gl9B:
undetectable		 3vywA-1gl9B:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 TYR B1047
GLY B 564
GLY B 567
LEU B 559
TYR B 578
 None
 1.01A 3vywD-1gl9B:
3.0		 3vywD-1gl9B:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP B 856
ARG B 377
ASP B 881
 None
 0.82A 4fp9D-1gl9B:
undetectable		 4fp9D-1gl9B:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP B 856
ARG B 377
ASP B 881
 None
 0.79A 4fzvA-1gl9B:
undetectable		 4fzvA-1gl9B:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 5 TYR B 545
LYS B 544
LEU B 667
GLU B 671
 None
 1.39A 4olaA-1gl9B:
4.0		 4olaA-1gl9B:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA902_0
(PROTEIN ARGONAUTE-2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 5 TYR B 545
LYS B 544
LEU B 667
GLU B 671
 None
 1.29A 4olbA-1gl9B:
4.7		 4olbA-1gl9B:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 8 LEU B 274
VAL B 257
VAL B 347
LEU B 484
 None
 1.16A 4q0bA-1gl9B:
0.0		 4q0bA-1gl9B:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 8 GLY B 821
GLN B 822
PHE B 887
SER B 890
 None
 0.76A 4ws1A-1gl9B:
3.4		 4ws1A-1gl9B:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		3 / 4 ARG B 968
GLY B 969
GLU B1019
 None
 0.65A 4z2dB-1gl9B:
2.5
4z2dC-1gl9B:
7.8		 4z2dB-1gl9B:
19.81
4z2dC-1gl9B:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 TYR B 545
LYS B 544
LEU B 667
GLU B 671
 None
 1.37A 4z4cA-1gl9B:
3.5		 4z4cA-1gl9B:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 5 TYR B 545
LYS B 544
LEU B 667
GLU B 671
 None
 1.42A 4z4dA-1gl9B:
4.5		 4z4dA-1gl9B:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 5 TYR B 545
LYS B 544
LEU B 667
GLU B 671
 None
 1.45A 4z4hA-1gl9B:
4.2		 4z4hA-1gl9B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 7 LYS B 701
ARG B1012
ILE B1053
TYR B1013
 None
 1.29A 5a06B-1gl9B:
2.3		 5a06B-1gl9B:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU B 484
LEU B 452
LEU B 267
PHE B 481
GLU B 255
 None
 1.33A 5ieoA-1gl9B:
2.9		 5ieoA-1gl9B:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 5 TYR B 545
LYS B 544
LEU B 667
GLU B 671
 None
 1.22A 5js1A-1gl9B:
4.5		 5js1A-1gl9B:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		3 / 3 LYS B 196
ASP B 195
ARG B 171
 None
 1.06A 5jwaA-1gl9B:
0.0
5jwaH-1gl9B:
0.0		 5jwaA-1gl9B:
19.64
5jwaH-1gl9B:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 GLY B 434
THR B 436
SER B 437
GLY B 447
 None
 0.73A 5k4pA-1gl9B:
0.0		 5k4pA-1gl9B:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 11 LEU B1009
GLU B 690
LEU B 702
VAL B 697
ALA B 713
 None
 1.00A 5o96G-1gl9B:
2.2		 5o96G-1gl9B:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 6 VAL B 628
THR B 630
LEU B 532
GLU B 539
 None
 0.92A 5tudD-1gl9B:
0.1		 5tudD-1gl9B:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		3 / 3 PHE B 473
ASP B 256
LEU B 458
 None
 0.75A 5uhcC-1gl9B:
2.4		 5uhcC-1gl9B:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 5 TYR B 545
LYS B 544
LEU B 667
GLU B 671
 None
 1.18A 5weaA-1gl9B:
4.8		 5weaA-1gl9B:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 GLY B 636
GLY B 554
LEU B 680
ASP B 677
ASP B 631
 None
 1.31A 5yn6A-1gl9B:
1.2		 5yn6A-1gl9B:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		5 / 12 GLY B 636
GLY B 554
LEU B 680
ASP B 677
ASP B 631
 None
 1.33A 5yniA-1gl9B:
undetectable		 5yniA-1gl9B:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 1gl9 REVERSE GYRASE
(Archaeoglobus
fulgidus) 		4 / 5 TYR B 545
LYS B 544
LEU B 667
GLU B 671
 None
 1.31A 6cbdA-1gl9B:
4.1		 6cbdA-1gl9B:
22.12