SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 ALA Y 100
VAL Y  88
TRP Y  89
 None
 0.85A 1av2C-1gllY:
undetectable
1av2D-1gllY:
undetectable		 1av2C-1gllY:
3.64
1av2D-1gllY:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 8 PHE Y 136
TYR Y 135
PHE Y 307
LEU Y 287
VAL Y 131
 None
GOL  Y 600 (-4.6A)
None
None
None
 1.40A 1fslA-1gllY:
1.7		 1fslA-1gllY:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 9 ALA Y 444
GLY Y 241
ILE Y  79
ILE Y  74
ILE Y   6
 None
 0.97A 1hshB-1gllY:
undetectable		 1hshB-1gllY:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 ALA Y 100
VAL Y  88
TRP Y  89
 None
 0.89A 1nt6B-1gllY:
undetectable		 1nt6B-1gllY:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 LEU Y 169
ILE Y 170
VAL Y 180
ASN Y 185
MET Y 173
 None
 1.31A 1wsvA-1gllY:
0.0		 1wsvA-1gllY:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 THR Y 267
GLY Y 266
GLY Y 410
THR Y 264
GLN Y 246
 ACP  Y 601 (-3.6A)
ACP  Y 601 (-3.6A)
ACP  Y 601 ( 4.2A)
None
GOL  Y 600 (-3.2A)
 1.32A 2azxA-1gllY:
undetectable		 2azxA-1gllY:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 THR Y 267
GLY Y 266
GLY Y 410
THR Y 264
GLN Y 246
 ACP  Y 601 (-3.6A)
ACP  Y 601 (-3.6A)
ACP  Y 601 ( 4.2A)
None
GOL  Y 600 (-3.2A)
 1.28A 2azxB-1gllY:
undetectable		 2azxB-1gllY:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 SER Y 221
GLY Y 442
ALA Y 444
GLY Y  78
LEU Y 254
 None
 0.90A 2nyuA-1gllY:
undetectable		 2nyuA-1gllY:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 SER Y 221
GLY Y 442
ALA Y 444
GLY Y  78
LEU Y 254
 None
 0.94A 2nyuB-1gllY:
undetectable		 2nyuB-1gllY:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 6 GLU Y 277
ALA Y 301
ASN Y 274
ALA Y 291
 None
 1.17A 2zgwB-1gllY:
0.3		 2zgwB-1gllY:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 11 LEU Y  64
ALA Y  18
ALA Y   8
TYR Y   5
GLN Y  73
 None
 1.24A 3bszF-1gllY:
0.0		 3bszF-1gllY:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_C_TMQC613_1
(DHFR-TS)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 ALA Y 447
ILE Y 239
ILE Y 229
LEU Y  64
ILE Y  74
 None
 0.82A 3clbC-1gllY:
undetectable		 3clbC-1gllY:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 8 GLY Y 448
ALA Y 447
GLY Y 442
LEU Y 441
VAL Y  20
 None
 1.46A 3em6A-1gllY:
undetectable		 3em6A-1gllY:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 4 LEU Y 191
ALA Y 186
VAL Y 217
PRO Y 215
 None
 0.93A 3gv1B-1gllY:
0.0		 3gv1B-1gllY:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_C_TMQC613_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 11 ALA Y 447
ILE Y 239
ILE Y 229
LEU Y  64
ILE Y  74
 None
 0.87A 3hbbC-1gllY:
undetectable		 3hbbC-1gllY:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 10 ALA Y 412
LEU Y 418
ALA Y 379
THR Y 339
VAL Y 336
 ACP  Y 601 (-3.9A)
None
None
None
None
 1.21A 3r9cA-1gllY:
undetectable		 3r9cA-1gllY:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 SER Y 383
GLN Y 387
PHE Y 348
GLY Y 362
GLY Y 350
 None
 1.14A 3tegA-1gllY:
undetectable		 3tegA-1gllY:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 7 ILE Y  74
ILE Y 229
SER Y  29
GLU Y  62
 None
 0.85A 3ua5B-1gllY:
0.0		 3ua5B-1gllY:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 ASP Y 133
GLY Y 352
TYR Y 135
 None
None
GOL  Y 600 (-4.6A)
 0.79A 3w9tC-1gllY:
undetectable		 3w9tC-1gllY:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 ASP Y 133
GLY Y 352
TYR Y 135
 None
None
GOL  Y 600 (-4.6A)
 0.79A 3w9tG-1gllY:
0.0		 3w9tG-1gllY:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 GLU Y 222
TYR Y 224
SER Y 240
 None
 0.92A 4at0A-1gllY:
0.0		 4at0A-1gllY:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 ARG Y 106
THR Y  85
TRP Y 103
 None
None
GOL  Y 600 ( 3.6A)
 1.19A 4d7hA-1gllY:
0.2		 4d7hA-1gllY:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 7 ILE Y 313
THR Y 380
SER Y 329
ASP Y 409
 ACP  Y 601 (-3.9A)
None
ACP  Y 601 (-3.0A)
None
 1.18A 4iarA-1gllY:
undetectable		 4iarA-1gllY:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 GLY Y 442
GLY Y 252
LEU Y 449
ALA Y 447
ILE Y   6
 None
 1.06A 4krhA-1gllY:
undetectable		 4krhA-1gllY:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 GLY Y 442
GLY Y 252
LEU Y 449
ALA Y 447
ILE Y   6
 None
 1.06A 4krhB-1gllY:
undetectable		 4krhB-1gllY:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 8 ALA Y  18
ASP Y 166
ILE Y  79
ILE Y 239
 None
 0.86A 4kttD-1gllY:
undetectable		 4kttD-1gllY:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 8 ALA Y 373
ASP Y 325
ILE Y 323
ILE Y 313
 None
None
None
ACP  Y 601 (-3.9A)
 0.93A 4ndnD-1gllY:
undetectable		 4ndnD-1gllY:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 MET Y 203
VAL Y 206
LEU Y 207
ILE Y 132
LEU Y 120
 None
 1.09A 4o1zB-1gllY:
0.0		 4o1zB-1gllY:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 ARG Y 106
THR Y  85
TRP Y 103
 None
None
GOL  Y 600 ( 3.6A)
 1.15A 4ug5A-1gllY:
0.0		 4ug5A-1gllY:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 ARG Y 106
THR Y  85
TRP Y 103
 None
None
GOL  Y 600 ( 3.6A)
 1.18A 4uglA-1gllY:
0.2		 4uglA-1gllY:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 GLY Y 244
LEU Y 250
GLY Y 241
ILE Y  79
GLY Y 252
 None
 1.01A 5d4uC-1gllY:
undetectable		 5d4uC-1gllY:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 GLY Y 244
LEU Y 250
GLY Y 241
ILE Y  79
GLY Y 252
 None
 1.01A 5d4uD-1gllY:
undetectable		 5d4uD-1gllY:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 ARG Y 106
THR Y  85
TRP Y 103
 None
None
GOL  Y 600 ( 3.6A)
 1.16A 5g6cA-1gllY:
0.0		 5g6cA-1gllY:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 6 ILE Y 425
ARG Y 389
TYR Y 483
TYR Y 355
 None
 1.19A 5igyA-1gllY:
0.0		 5igyA-1gllY:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 6 PHE Y 365
TYR Y 343
TYR Y 483
PHE Y 421
 None
 1.39A 5lrbA-1gllY:
undetectable		 5lrbA-1gllY:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A220_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 9 LEU Y 406
VAL Y 408
LEU Y 250
THR Y 388
VAL Y 391
 None
 1.27A 5mxbA-1gllY:
undetectable		 5mxbA-1gllY:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		4 / 8 THR Y 181
TYR Y 183
ARG Y  83
GLN Y 247
 None
None
GOL  Y 600 (-4.0A)
None
 1.39A 5tzoB-1gllY:
undetectable		 5tzoB-1gllY:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 LEU Y 272
THR Y  80
ASN Y  81
 None
 0.67A 6baaE-1gllY:
0.0		 6baaE-1gllY:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 LEU Y 272
THR Y  80
ASN Y  81
 None
 0.67A 6baaF-1gllY:
undetectable		 6baaF-1gllY:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 LEU Y 272
THR Y  80
ASN Y  81
 None
 0.68A 6baaG-1gllY:
undetectable		 6baaG-1gllY:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 LEU Y 272
THR Y  80
ASN Y  81
 None
 0.68A 6baaH-1gllY:
undetectable		 6baaH-1gllY:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		5 / 12 VAL Y  30
VAL Y  19
GLY Y 410
THR Y  13
GLY Y  12
 None
None
ACP  Y 601 ( 4.2A)
ACP  Y 601 (-3.4A)
ACP  Y 601 (-2.9A)
 1.04A 6brdC-1gllY:
undetectable		 6brdC-1gllY:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1gll GLYCEROL KINASE
(Escherichia
coli) 		3 / 3 GLY Y  12
ASP Y  10
ILE Y  79
 ACP  Y 601 (-2.9A)
MG  Y 602 ( 3.7A)
None
 0.59A 6dgxB-1gllY:
0.0		 6dgxB-1gllY:
10.29