SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1glv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 1glv GLUTATHIONE SYNTHASE
(Escherichia
coli) 		4 / 8 GLY A 227
GLY A 226
GLY A 207
ILE A 275
 None
 0.69A 3d41A-1glvA:
3.0		 3d41A-1glvA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 1glv GLUTATHIONE SYNTHASE
(Escherichia
coli) 		3 / 3 GLU A 137
PHE A 150
GLN A 198
 None
 0.99A 3r55A-1glvA:
0.0		 3r55A-1glvA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 1glv GLUTATHIONE SYNTHASE
(Escherichia
coli) 		4 / 5 ASP A 273
LEU A 272
PRO A 287
PHE A 269
 None
 1.21A 3s3vA-1glvA:
0.0		 3s3vA-1glvA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 1glv GLUTATHIONE SYNTHASE
(Escherichia
coli) 		3 / 3 GLY A   5
LEU A  80
HIS A  36
 None
 0.63A 5u63A-1glvA:
undetectable		 5u63A-1glvA:
26.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 1glv GLUTATHIONE SYNTHASE
(Escherichia
coli) 		3 / 3 GLY A   5
LEU A  80
HIS A  36
 None
 0.62A 5u63B-1glvA:
undetectable		 5u63B-1glvA:
26.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 1glv GLUTATHIONE SYNTHASE
(Escherichia
coli) 		4 / 6 ARG A 291
PHE A 297
ILE A 301
THR A 302
 None
 1.17A 5vceA-1glvA:
0.0		 5vceA-1glvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1glv GLUTATHIONE SYNTHASE
(Escherichia
coli) 		4 / 6 ARG A 312
VAL A  82
LEU A 313
ARG A  31
 None
 0.91A 5x7zA-1glvA:
0.0		 5x7zA-1glvA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1glv GLUTATHIONE SYNTHASE
(Escherichia
coli) 		3 / 3 TYR A  37
ALA A  52
LEU A  43
 None
 0.51A 6ag0C-1glvA:
undetectable		 6ag0C-1glvA:
15.33