SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gm1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		4 / 6 GLN A 100
TYR A  43
VAL A  37
GLY A  41
 None
 1.20A 1ekjC-1gm1A:
undetectable
1ekjD-1gm1A:
undetectable		 1ekjC-1gm1A:
21.50
1ekjD-1gm1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		4 / 6 VAL A  37
GLY A  41
GLN A 100
TYR A  43
 None
 1.27A 1ekjC-1gm1A:
undetectable
1ekjD-1gm1A:
undetectable		 1ekjC-1gm1A:
21.50
1ekjD-1gm1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		4 / 8 GLN A 100
VAL A  37
GLY A  41
GLY A  32
 None
 0.88A 1ekjE-1gm1A:
0.0
1ekjF-1gm1A:
0.0		 1ekjE-1gm1A:
21.50
1ekjF-1gm1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		5 / 8 ALA A  52
LEU A  25
LEU A  85
ILE A  59
VAL A  29
 None
 1.42A 2uxpA-1gm1A:
undetectable		 2uxpA-1gm1A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		4 / 8 VAL A  82
LEU A  18
GLY A  26
ALA A  53
 None
 0.95A 2xfsA-1gm1A:
undetectable		 2xfsA-1gm1A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		4 / 8 VAL A  82
LEU A  18
GLY A  26
ALA A  53
 None
 0.95A 2xh9A-1gm1A:
undetectable		 2xh9A-1gm1A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		4 / 8 GLN A  80
ASN A  34
LYS A  45
THR A  30
 None
 1.45A 4d1yA-1gm1A:
undetectable
4d1yB-1gm1A:
undetectable		 4d1yA-1gm1A:
18.18
4d1yB-1gm1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		5 / 11 ILE A  27
ALA A  81
LEU A  85
THR A  84
LEU A  94
 None
 1.14A 4g1bB-1gm1A:
undetectable		 4g1bB-1gm1A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 1gm1 PROTEIN TYROSINE
PHOSPHATASE
(Mus
musculus) 		4 / 5 VAL A  16
HIS A  60
LEU A  25
ASP A  63
 None
 1.29A 5vcvA-1gm1A:
undetectable		 5vcvA-1gm1A:
14.65