SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ETA_2_T442129_1 (TRANSTHYRETIN)	1gmv	UREE (Klebsiella aerogenes)	4 / 5	LEU A 4 GLU A 63 ALA A 40 LEU A 42	None	0.91A	1eta2-1gmvA: undetectable	1eta2-1gmvA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1gmv	UREE (Klebsiella aerogenes)	4 / 8	LEU A 99 ILE A 101 LEU A 106 LEU A 92	None	0.80A	2xfhA-1gmvA: undetectable	2xfhA-1gmvA: 18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U40_F_ADNF251_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1gmv	UREE (Klebsiella aerogenes)	5 / 10	MET A 102 ARG A 78 VAL A 74 GLU A 105 ASP A 71	None	1.43A	3u40A-1gmvA: undetectable 3u40F-1gmvA: undetectable	3u40A-1gmvA: 20.25 3u40F-1gmvA: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IIZ_B_LURB201_1 (TRANSTHYRETIN)	1gmv	UREE (Klebsiella aerogenes)	4 / 8	LEU A 4 GLU A 63 ALA A 40 LEU A 42	None	0.94A	4iizB-1gmvA: undetectable	4iizB-1gmvA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EF6_A_ACTA405_0 (AMINOGLYCOSIDE PHOSPHOTRANSFERASE)	1gmv	UREE (Klebsiella aerogenes)	4 / 6	ARG A 51 PRO A 131 GLN A 100 ILE A 22	None	1.16A	6ef6A-1gmvA: 0.1	6ef6A-1gmvA: 19.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ETA_2_T442129_1","TRANSTHYRETIN","1gmv","UREE","Klebsiella aerogenes",4,"LEU A   4;GLU A  63;ALA A  40;LEU A  42","None","0.91A","1eta2-1gmvA:undetectable","1eta2-1gmvA:22.45"],["2XFH_A_CL6A1414_1","ERYTHROMYCIN B\/D C-12 HYDROXYLASE","1gmv","UREE","Klebsiella aerogenes",4,"LEU A  99;ILE A 101;LEU A 106;LEU A  92","None","0.80A","2xfhA-1gmvA:undetectable","2xfhA-1gmvA:18.25"],["3U40_F_ADNF251_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1gmv","UREE","Klebsiella aerogenes",5,"MET A 102;ARG A  78;VAL A  74;GLU A 105;ASP A  71","None","1.43A","3u40A-1gmvA:undetectable;3u40F-1gmvA:undetectable","3u40A-1gmvA:20.25;3u40F-1gmvA:20.25"],["4IIZ_B_LURB201_1","TRANSTHYRETIN","1gmv","UREE","Klebsiella aerogenes",4,"LEU A   4;GLU A  63;ALA A  40;LEU A  42","None","0.94A","4iizB-1gmvA:undetectable","4iizB-1gmvA:22.45"],["6EF6_A_ACTA405_0","AMINOGLYCOSIDE PHOSPHOTRANSFERASE","1gmv","UREE","Klebsiella aerogenes",4,"ARG A  51;PRO A 131;GLN A 100;ILE A  22","None","1.16A","6ef6A-1gmvA:0.1","6ef6A-1gmvA:19.53"]]