SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gmx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 1gmx THIOSULFATE
SULFURTRANSFERASE
GLPE
(Escherichia
coli) 		5 / 12 ILE A  89
LEU A  16
GLY A  91
GLY A  92
LEU A  23
 None
 1.03A 1liiA-1gmxA:
undetectable		 1liiA-1gmxA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 1gmx THIOSULFATE
SULFURTRANSFERASE
GLPE
(Escherichia
coli) 		4 / 5 LEU A  23
ASP A  25
ALA A  40
ILE A  89
 None
 1.14A 2qhfA-1gmxA:
undetectable		 2qhfA-1gmxA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1gmx THIOSULFATE
SULFURTRANSFERASE
GLPE
(Escherichia
coli) 		4 / 7 LYS A  15
ASP A  11
ILE A   7
TYR A  87
 None
None
None
EDO  A1114 ( 4.2A)
 1.39A 5a06B-1gmxA:
1.3		 5a06B-1gmxA:
16.23