SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gmz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		4 / 7 VAL A  30
TYR A 107
TYR A 110
GLY A  29
 None
 0.99A 1lweA-1gmzA:
undetectable		 1lweA-1gmzA:
12.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		4 / 7 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.34A 1th6A-1gmzA:
20.2		 1th6A-1gmzA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		4 / 7 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.36A 2armA-1gmzA:
20.1		 2armA-1gmzA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		5 / 10 LEU A   2
HIS A  47
ASP A  48
LYS A  60
PHE A  96
 None
 0.54A 2b17A-1gmzA:
20.4		 2b17A-1gmzA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		4 / 6 LEU A   2
HIS A  47
ASP A  48
TYR A  51
 None
 0.34A 2dpzA-1gmzA:
20.7		 2dpzA-1gmzA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		3 / 3 ASP A  48
TYR A  51
LYS A  60
 None
 0.64A 2othA-1gmzA:
20.4		 2othA-1gmzA:
64.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		3 / 3 ASP A 101
THR A  72
GLU A  98
 None
 0.70A 2zifB-1gmzA:
undetectable		 2zifB-1gmzA:
14.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_3
(PHOSPHOLIPASE A2)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
 0.68A 3bjwG-1gmzA:
19.7		 3bjwG-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
 0.81A 3bjwA-1gmzA:
19.7		 3bjwA-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		5 / 12 GLY A   6
LYS A  15
PRO A  17
PHE A  18
PRO A  19
 None
 0.53A 3bjwF-1gmzA:
19.5		 3bjwF-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		5 / 12 ILE A   9
LYS A  15
PHE A  18
PRO A  19
THR A  23
 None
 1.26A 3bjwF-1gmzA:
19.5		 3bjwF-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		4 / 8 LYS A  15
TYR A 103
ASN A 104
LYS A 105
 None
 0.96A 3bjwD-1gmzA:
19.7		 3bjwD-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_1
(PHOSPHOLIPASE A2)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
 0.95A 3bjwC-1gmzA:
19.7		 3bjwC-1gmzA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		5 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
 0.49A 3fo7A-1gmzA:
20.1		 3fo7A-1gmzA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		4 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.40A 3h1xA-1gmzA:
20.2		 3h1xA-1gmzA:
64.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		5 / 9 VAL A  46
ALA A  92
PHE A  96
TYR A 103
TYR A  24
 None
 1.39A 4lb2B-1gmzA:
2.1		 4lb2B-1gmzA:
11.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1gmz PHOSPHOLIPASE A2
(Bothrops
pirajai) 		4 / 7 ASN A 104
LYS A 105
LYS A 106
LEU A 114
 None
 0.88A 4yv5B-1gmzA:
19.2		 4yv5B-1gmzA:
71.54